Showing entry for Cysteine dioxygenase type 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013687
Protein NameCysteine dioxygenase type 1
Uniport IdQ16878
GeneCDO1
Gene Id1036
DomainCDO_I
Pfam PF05995  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00270 Cysteine and methionine metabolism
1. Metabolism 1.6 Metabolism of other amino acids hsa00430 Taurine and hypotaurine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006534 cysteine metabolic process
Biological Process GO:0006954 inflammatory response
Biological Process GO:0007595 lactation
Biological Process GO:0019448 L-cysteine catabolic process
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0043200 response to amino acid
Biological Process GO:0051591 response to cAMP
Biological Process GO:0045471 response to ethanol
Biological Process GO:0033762 response to glucagon
Biological Process GO:0051384 response to glucocorticoid
Biological Process GO:0000097 sulfur amino acid biosynthetic process
Biological Process GO:0042412 taurine biosynthetic process
molecular function GO:0017172 cysteine dioxygenase activity
molecular function GO:0008198 ferrous iron binding
molecular function GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1614558 Degradation of cysteine and homocysteine
R-HSA-1614635 Sulfur amino acid metabolism
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0016977 BXGD001086 Gall Bladder Diseases Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0022521 BXGD001549 Kartagener Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases; Cardiovascular Diseases
C0023269 BXGD001627 leiomyosarcoma Neoplasms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0026948 BXGD001952 Mycosis Fungoides Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0036920 BXGD002645 Sezary Syndrome Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0037221 BXGD002673 Situs Inversus Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0151517 BXGD003431 Complete atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0153425 BXGD003641 Malignant tumor of small intestine Digestive System Diseases; Neoplasms
C0153452 BXGD003647 Malignant neoplasm of gallbladder Digestive System Diseases; Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0235782 BXGD004769 Gallbladder Carcinoma Digestive System Diseases; Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238196 BXGD004891 Small intestine carcinoma Digestive System Diseases; Neoplasms
C0242596 BXGD005181 Neoplasm, Residual Pathological Conditions, Signs and Symptoms; Neoplasms
C0278480 BXGD006510 Stage III Colon Cancer Digestive System Diseases; Neoplasms
C0278607 BXGD006548 Adult Leiomyosarcoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279986 BXGD006705 Childhood Leiomyosarcoma Neoplasms
C0280217 BXGD006720 stage, non-small cell lung cancer Neoplasms; Respiratory Tract Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0524909 BXGD009247 Hepatitis B, Chronic Digestive System Diseases; Infections
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0750952 BXGD010263 Biliary Tract Cancer Digestive System Diseases; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1337035 BXGD012878 Xanthogranulomatous cholecystitis Digestive System Diseases; Nutritional and Metabolic Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3146254 BXGD018263 Stage III Colon Cancer AJCC v7
C3805278 BXGD019474 Extrahepatic Cholangiocarcinoma Neoplasms
C4525124 BXGD023120 Stage III Colon Cancer AJCC v8
C4525297 BXGD023131 Stage 0 Gallbladder Cancer AJCC v8
C4525300 BXGD023132 Stage IIA Gallbladder Cancer AJCC v8
C4525301 BXGD023133 Stage IIB Gallbladder Cancer AJCC v8
C4525302 BXGD023134 Stage III Gallbladder Cancer AJCC v8
C4525305 BXGD023135 Stage IV Gallbladder Cancer AJCC v8
C4551720 BXGD023400 Primary Ciliary Dyskinesia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0006271 L-Cysteine 121.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein