adisease

Showing entry for Mycosis Fungoides

General Disease Information
BXGD Id	BXGD001952
Disease Name	Mycosis Fungoides
Disease CUI Id	C0026948
MeSH Codes	C04 C20 C15
Disease Class Name	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7 DOID:14566
Disease Ontology Class Name	disease of anatomical entity; disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O43318	BXGT004586	Mitogen-activated protein kinase kinase kinase 7	6885	reviewed	Kinase
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O75362	BXGT005114	Zinc finger protein 217	7764	reviewed
O75604	BXGT005139	Ubiquitin carboxyl-terminal hydrolase 2	9099	reviewed	Enzyme
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P04264	BXGT006176	Keratin, type II cytoskeletal 1	3848	reviewed
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P10144	BXGT007541	Granzyme B	3002	reviewed	Enzyme
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P14151	BXGT007990	L-selectin	6402	reviewed
P14618	BXGT008027	Pyruvate kinase PKM	5315	reviewed	Kinase
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15144	BXGT008087	Aminopeptidase N	290	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16070	BXGT008186	CD44 antigen	960	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P22083	BXGT008727	Alpha-(1,3)-fucosyltransferase 4	2526	reviewed	Enzyme
P22681	BXGT008795	E3 ubiquitin-protein ligase CBL	867	reviewed	Enzyme
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P28072	BXGT009231	Proteasome subunit beta type-6	5694	reviewed
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35916	BXGT009881	Vascular endothelial growth factor receptor 3	2324	reviewed	Kinase
P37023	BXGT009953	Serine/threonine-protein kinase receptor R3	94	reviewed	Kinase
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40933	BXGT010209	Interleukin-15	3600	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P43489	BXGT010394	Tumor necrosis factor receptor superfamily member 4	7293	reviewed
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49116	BXGT010678	Nuclear receptor subfamily 2 group C member 2	7182	reviewed	Nuclear receptor
P49767	BXGT010739	Vascular endothelial growth factor C	7424	reviewed	Signaling
P51679	BXGT010877	C-C chemokine receptor type 4	1233	reviewed	G-protein coupled receptor
P52333	BXGT010928	Tyrosine-protein kinase JAK3	3718	reviewed	Kinase
P54578	BXGT011056	Ubiquitin carboxyl-terminal hydrolase 14	9097	reviewed	Enzyme
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P61978	BXGT011399	Heterogeneous nuclear ribonucleoprotein K	3190	reviewed	Enzyme
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P78556	BXGT011849	C-C motif chemokine 20	6364	reviewed	Signaling
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q02790	BXGT012672	Peptidyl-prolyl cis-trans isomerase FKBP4	2288	reviewed	Enzyme
Q13126	BXGT013313	S-methyl-5'-thioadenosine phosphorylase	4507	reviewed	Enzyme
Q13153	BXGT013319	Serine/threonine-protein kinase PAK 1	5058	reviewed	Kinase
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13451	BXGT013356	Peptidyl-prolyl cis-trans isomerase FKBP5	2289	reviewed	Enzyme
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16878	BXGT013687	Cysteine dioxygenase type 1	1036	reviewed
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q8TCT9	BXGT018801	Minor histocompatibility antigen H13	81502	reviewed	Enzyme
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q92769	BXGT019370	Histone deacetylase 2	3066	reviewed	Epigenetic regulator
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q9BXR0	BXGT020173	Queuine tRNA-ribosyltransferase catalytic subunit 1	81890	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9NR28	BXGT021178	Diablo homolog, mitochondrial	56616	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRW4	BXGT021196	Dual specificity protein phosphatase 22	56940	reviewed
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UM73	BXGT021773	ALK tyrosine kinase receptor	238	reviewed	Kinase
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P17535	BXGT023437	Transcription factor jun-D	3727	reviewed	Transcription factor
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
P09471	BXGT026153	Guanine nucleotide-binding protein G(o) subunit alpha	2775	reviewed	Enzyme modulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}