Showing entry for Multidrug resistance-associated protein 7


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT015846
Protein NameMultidrug resistance-associated protein 7
Uniport IdQ5T3U5
GeneABCC10
Gene Id89845
DomainABC_membrane; ABC_tran
Pfam PF00664   PF00005  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.1 Membrane transport hsa02010 ABC transporters
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0055085 transmembrane transport
molecular function GO:0016887 ATPase activity
molecular function GO:0042626 ATPase-coupled transmembrane transporter activity
molecular function GO:0005524 ATP binding
cellular component GO:0016021 integral component of membrane
cellular component GO:0005765 lysosomal membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-382556 ABC-family proteins mediated transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0018671 BXGD001211 Head and Neck Neoplasms Neoplasms
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0151747 BXGD003471 Renal tubular disorder Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0220621 BXGD004300 Childhood Acute Myeloid Leukemia Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0497169 BXGD009054 hiv-infection/aids Infections
C0596887 BXGD009648 mathematical ability
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0021688 alstolucine F 338.16
BXGC0027421 Paclitaxel 853.33
BXGC0034768 Vincristine 824.4
BXGC0034783 Doxorubicin 543.17
BXGC0044017 Verapamil 454.28
BXGC0050123 Cepharanthine 606.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein