Showing entry for Childhood Acute Myeloid Leukemia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004300
Disease NameChildhood Acute Myeloid Leukemia
Disease CUI IdC0220621
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00748 BXGT003942 Cocaine esterase 8824 reviewed Enzyme
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O15392 BXGT004162 Baculoviral IAP repeat-containing protein 5 332 reviewed Enzyme modulator
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75340 BXGT005112 Programmed cell death protein 6 10016 reviewed
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P00846 BXGT005674 ATP synthase subunit a 4508 reviewed Transporter
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P03897 BXGT006111 NADH-ubiquinone oxidoreductase chain 3 4537 reviewed
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06748 BXGT006497 Nucleophosmin 4869 reviewed Chaperone
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07355 BXGT006609 Annexin A2 302 reviewed
P07711 BXGT006661 Cathepsin L1 1514 reviewed Enzyme
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08700 BXGT006816 Interleukin-3 3562 reviewed
P08865 BXGT006832 40S ribosomal protein SA 3921 reviewed Nucleic acid binding
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P0DP23 BXGT007520 Calmodulin-1 808 reviewed
P0DP24 BXGT007521 Calmodulin-2 808 reviewed
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18433 BXGT008403 Receptor-type tyrosine-protein phosphatase alpha 5786 reviewed Enzyme
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P20701 BXGT008591 Integrin alpha-L 3683 reviewed
P25713 BXGT009062 Metallothionein-3 4504 reviewed
P26951 BXGT009147 Interleukin-3 receptor subunit alpha 3563 reviewed Signaling
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P31785 BXGT009577 Cytokine receptor common subunit gamma 3561 reviewed Signaling
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P35658 BXGT009859 Nuclear pore complex protein Nup214 8021 reviewed Nucleic acid binding
P36551 BXGT009927 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 1371 reviewed Enzyme
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P40225 BXGT010168 Thrombopoietin 7066 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P55157 BXGT011108 Microsomal triglyceride transfer protein large subunit 4547 reviewed Transporter
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60842 BXGT011330 Eukaryotic initiation factor 4A-I 1973 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P62258 BXGT011415 14-3-3 protein epsilon 7531 reviewed Chaperone
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01081 BXGT012566 Splicing factor U2AF 35 kDa subunit 7307 reviewed
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 3757 reviewed Ion channel
Q13206 BXGT013326 Probable ATP-dependent RNA helicase DDX10 1662 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13951 BXGT013407 Core-binding factor subunit beta 865 reviewed
Q14141 BXGT013447 Septin-6 23157 reviewed Enzyme modulator
Q14240 BXGT013458 Eukaryotic initiation factor 4A-II 1974 reviewed
Q15125 BXGT013543 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 10682 reviewed Enzyme
Q15596 BXGT013582 Nuclear receptor coactivator 2 10499 reviewed Enzyme
Q5T3U5 BXGT015846 Multidrug resistance-associated protein 7 89845 reviewed Transporter
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q7L266 BXGT016993 Isoaspartyl peptidase/L-asparaginase 80150 reviewed Enzyme
Q8TAI7 BXGT018787 GTPase RhebL1 121268 reviewed Enzyme modulator
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q92794 BXGT019375 Histone acetyltransferase KAT6A 7994 reviewed Enzyme
Q92859 BXGT019386 Neogenin 4756 reviewed
Q9H4W6 BXGT020478 Transcription factor COE3 253738 reviewed
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 11040 reviewed Kinase
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9Y5S1 BXGT022300 Transient receptor potential cation channel subfamily V member 2 51393 reviewed Ion channel
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
P20138 BXGT023857 Myeloid cell surface antigen CD33 945 reviewed Receptor
P29590 BXGT024350 Protein PML 5371 reviewed
P0DP25 BXGT024595 Calmodulin-3 808 reviewed
Q96L73 BXGT024676 Histone-lysine N-methyltransferase, H3 lysine-36 specific 64324 reviewed Epigenetic regulator
Q92888 BXGT026130 Rho guanine nucleotide exchange factor 1 9138 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease