Showing entry for Serine/threonine-protein kinase TAO1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016997
Protein NameSerine/threonine-protein kinase TAO1
Uniport IdQ7L7X3
GeneTAOK1
Gene Id57551
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007257 activation of JUN kinase activity
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0032147 activation of protein kinase activity
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0006281 DNA repair
Biological Process GO:0097194 execution phase of apoptosis
Biological Process GO:0000226 microtubule cytoskeleton organization
Biological Process GO:0007095 mitotic G2 DNA damage checkpoint
Biological Process GO:0007026 negative regulation of microtubule depolymerization
Biological Process GO:0070050 neuron cellular homeostasis
Biological Process GO:0048812 neuron projection morphogenesis
Biological Process GO:0016310 phosphorylation
Biological Process GO:0046330 positive regulation of JNK cascade
Biological Process GO:1901985 positive regulation of protein acetylation
Biological Process GO:0032874 positive regulation of stress-activated MAPK cascade
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:0051493 regulation of cytoskeleton organization
Biological Process GO:0070507 regulation of microtubule cytoskeleton organization
Biological Process GO:0023014 signal transduction by protein phosphorylation
Biological Process GO:0031098 stress-activated protein kinase signaling cascade
molecular function GO:0043014 alpha-tubulin binding
molecular function GO:0005524 ATP binding
molecular function GO:0048487 beta-tubulin binding
molecular function GO:0016301 kinase activity
molecular function GO:0004672 protein kinase activity
molecular function GO:0043539 protein serine/threonine kinase activator activity
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0048156 tau protein binding
molecular function GO:0050321 tau-protein kinase activity
molecular function GO:0016740 transferase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0015630 microtubule cytoskeleton
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-141424 Amplification of signal from the kinetochores
R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-HSA-162582 Signal Transduction
R-HSA-1640170 Cell Cycle
R-HSA-194315 Signaling by Rho GTPases
R-HSA-195258 RHO GTPase Effectors
R-HSA-2467813 Separation of Sister Chromatids
R-HSA-2500257 Resolution of Sister Chromatid Cohesion
R-HSA-2555396 Mitotic Metaphase and Anaphase
R-HSA-5663220 RHO GTPases Activate Formins
R-HSA-68877 Mitotic Prometaphase
R-HSA-68882 Mitotic Anaphase
R-HSA-68886 M Phase
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69618 Mitotic Spindle Checkpoint
R-HSA-69620 Cell Cycle Checkpoints
R-HSA-9648025 EML4 and NUDC in mitotic spindle formation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0018781 BXGD001219 Noise-induced hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0032181 BXGD002332 Platelet Count measurement
C0032584 BXGD002363 polyps Pathological Conditions, Signs and Symptoms
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0200665 BXGD004045 Platelet mean volume determination (procedure)
C0205682 BXGD004105 Waist-Hip Ratio
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0557874 BXGD009444 Global developmental delay
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4225275 BXGD022206 MENTAL RETARDATION, AUTOSOMAL DOMINANT 40
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012352 Chelerythrine 348.12
BXGC0013109 4-[2-(3,5-Dihydroxyphenyl)Ethenyl]Benzene-1,2-Diol 244.07
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein