Showing entry for Ferritin, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018511
Protein NameFerritin, mitochondrial
Uniport IdQ8N4E7
GeneFTMT
Gene Id94033
DomainFerritin
Pfam PF00210  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.2 Cell growth and death hsa04216 Ferroptosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006879 cellular iron ion homeostasis
Biological Process GO:0006880 intracellular sequestering of iron ion
Biological Process GO:0006826 iron ion transport
Biological Process GO:1904234 positive regulation of aconitate hydratase activity
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0051349 positive regulation of lyase activity
Biological Process GO:1904231 positive regulation of succinate dehydrogenase activity
molecular function GO:0008199 ferric iron binding
molecular function GO:0008198 ferrous iron binding
molecular function GO:0004322 ferroxidase activity
molecular function GO:0005506 iron ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-917937 Iron uptake and transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002312 BXGD000107 alpha-Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002893 BXGD000150 Refractory anemias Hemic and Lymphatic Diseases
C0002896 BXGD000153 Sideroblastic anemia Hemic and Lymphatic Diseases
C0004106 BXGD000254 Astigmatism Eye Diseases
C0016719 BXGD001074 Friedreich Ataxia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0282193 BXGD006798 Iron Overload Nutritional and Metabolic Diseases
C0392475 BXGD008045 Roberts-SC phocomelia syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C1264195 BXGD011913 Refractory anemia with ringed sideroblasts Hemic and Lymphatic Diseases
C1305968 BXGD012350 Eccrine dermal cylindroma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1456873 BXGD013129 alpha^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1853578 BXGD015346 Neuroferritinopathy Nutritional and Metabolic Diseases; Nervous System Diseases
C1856689 BXGD015630 FRIEDREICH ATAXIA 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C2981142 BXGD018210 Refractory anemia, without ringed sideroblasts, without excess blasts Hemic and Lymphatic Diseases
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4551511 BXGD023330 X-linked sideroblastic anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein