adisease

Showing entry for Astigmatism

General Disease Information
BXGD Id	BXGD000254
Disease Name	Astigmatism
Disease CUI Id	C0004106
MeSH Codes	C11
Disease Class Name	Eye Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000478
Human Phenotype Ontology Term	Abnormality of the eye
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O60840	BXGT004901	Voltage-dependent L-type calcium channel subunit alpha-1F	778	reviewed	Ion channel
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P10412	BXGT007566	Histone H1.4	3008	reviewed	Nucleic acid binding
P12081	BXGT007772	Histidine--tRNA ligase, cytoplasmic	3035	reviewed	Enzyme
P14679	BXGT008039	Tyrosinase	7299	reviewed	Enzyme
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P23246	BXGT008840	Splicing factor, proline- and glutamine-rich	6421	reviewed	Nucleic acid binding
P26640	BXGT009123	Valine--tRNA ligase	7407	reviewed
P28347	BXGT009257	Transcriptional enhancer factor TEF-1	7003	reviewed	Transcription factor
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P48167	BXGT010621	Glycine receptor subunit beta	2743	reviewed	Ion channel
P49585	BXGT010712	Choline-phosphate cytidylyltransferase A	5130	reviewed
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q07021	BXGT012915	Complement component 1 Q subcomponent-binding protein, mitochondrial	708	reviewed
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13535	BXGT013370	Serine/threonine-protein kinase ATR	545	reviewed	Kinase
Q14004	BXGT013435	Cyclin-dependent kinase 13	8621	reviewed	Kinase
Q14839	BXGT013509	Chromodomain-helicase-DNA-binding protein 4	1108	reviewed
Q6NUK1	BXGT016429	Calcium-binding mitochondrial carrier protein SCaMC-1	29957	reviewed	Transporter
Q6PCD5	BXGT016464	E3 ubiquitin-protein ligase RFWD3	55159	reviewed	Enzyme
Q86YC2	BXGT017633	Partner and localizer of BRCA2	79728	reviewed
Q8IYD8	BXGT018367	Fanconi anemia group M protein	57697	reviewed	Enzyme
Q8N4E7	BXGT018511	Ferritin, mitochondrial	94033	reviewed	Storage
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8WWQ0	BXGT019003	PH-interacting protein	55023	reviewed	Epigenetic regulator
Q96BI3	BXGT019623	Gamma-secretase subunit APH-1A	51107	reviewed	Enzyme modulator
Q9H4W6	BXGT020478	Transcription factor COE3	253738	reviewed
Q9HD42	BXGT020543	Charged multivesicular body protein 1a	5119	reviewed
Q9NPD8	BXGT021152	Ubiquitin-conjugating enzyme E2 T	29089	reviewed
Q9NPI8	BXGT021161	Fanconi anemia group F protein	2188	reviewed
Q9NW38	BXGT021230	E3 ubiquitin-protein ligase FANCL	55120	reviewed	Enzyme
Q9NXG6	BXGT021246	Transmembrane prolyl 4-hydroxylase	54681	reviewed
Q9UGL1	BXGT021685	Lysine-specific demethylase 5B	10765	reviewed	Epigenetic regulator
Q9UI95	BXGT021714	Mitotic spindle assembly checkpoint protein MAD2B	10459	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
P58215	BXGT026106	Lysyl oxidase homolog 3	84695	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}