Showing entry for Movement Disorders


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001913
Disease NameMovement Disorders
Disease CUI IdC0026650
MeSH Codes C10  
Disease Class NameNervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00189 BXGT003891 AP-4 complex subunit mu-1 9179 reviewed Extracellular structure
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O00571 BXGT003938 ATP-dependent RNA helicase DDX3X 1654 reviewed
O00754 BXGT003944 Lysosomal alpha-mannosidase 4125 reviewed
O14656 BXGT004080 Torsin-1A 1861 reviewed Chaperone
O14936 BXGT004114 Peripheral plasma membrane protein CASK 8573 reviewed Kinase
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 4864 reviewed Transporter
O15305 BXGT004152 Phosphomannomutase 2 5373 reviewed Enzyme
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O15409 BXGT004166 Forkhead box protein P2 93986 reviewed
O43464 BXGT004595 Serine protease HTRA2, mitochondrial 27429 reviewed
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O75899 BXGT005161 Gamma-aminobutyric acid type B receptor subunit 2 9568 reviewed G-protein coupled receptor
O76039 BXGT005171 Cyclin-dependent kinase-like 5 6792 reviewed Kinase
O94903 BXGT005339 Pyridoxal phosphate homeostasis protein 11212 reviewed
O95263 BXGT005366 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B 8622 reviewed
O95622 BXGT005386 Adenylate cyclase type 5 111 reviewed
O95970 BXGT005409 Leucine-rich glioma-inactivated protein 1 9211 reviewed
O96028 BXGT005417 Histone-lysine N-methyltransferase NSD2 7468 reviewed Epigenetic regulator
P00367 BXGT005517 Glutamate dehydrogenase 1, mitochondrial 2746 reviewed Enzyme
P00387 BXGT005525 NADH-cytochrome b5 reductase 3 1727 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02792 BXGT005966 Ferritin light chain 2512 reviewed Storage
P03915 BXGT006114 NADH-ubiquinone oxidoreductase chain 5 4540 reviewed Enzyme
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04156 BXGT006156 Major prion protein 5621 reviewed
P04350 BXGT006193 Tubulin beta-4A chain 10382 reviewed Cellular structure
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P06865 BXGT006516 Beta-hexosaminidase subunit alpha 3073 reviewed Enzyme
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07602 BXGT006646 Prosaposin 5660 reviewed
P08034 BXGT006716 Gap junction beta-1 protein 2705 reviewed Cell-cell junction
P08559 BXGT006788 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 5160 reviewed
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 6515 reviewed Transporter
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P12081 BXGT007772 Histidine--tRNA ligase, cytoplasmic 3035 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13637 BXGT007933 Sodium/potassium-transporting ATPase subunit alpha-3 478 reviewed Transporter
P14207 BXGT007993 Folate receptor beta 2350 reviewed
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15104 BXGT008081 Glutamine synthetase 2752 reviewed Enzyme
P15328 BXGT008108 Folate receptor alpha 2348 reviewed
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P16389 BXGT008221 Potassium voltage-gated channel subfamily A member 2 3737 reviewed Ion channel
P16499 BXGT008238 Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha 5145 reviewed
P18507 BXGT008411 Gamma-aminobutyric acid receptor subunit gamma-2 2566 reviewed Ion channel
P20711 BXGT008594 Aromatic-L-amino-acid decarboxylase 1644 reviewed
P20930 BXGT008616 Filaggrin 2312 reviewed Cellular structure
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21675 BXGT008678 Transcription initiation factor TFIID subunit 1 6872 reviewed Kinase
P21728 BXGT008686 D(1A) dopamine receptor 1812 reviewed G-protein coupled receptor
P21817 BXGT008693 Ryanodine receptor 1 6261 reviewed Ion channel
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P22681 BXGT008795 E3 ubiquitin-protein ligase CBL 867 reviewed Enzyme
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P28472 BXGT009260 Gamma-aminobutyric acid receptor subunit beta-3 2562 reviewed Ion channel
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29274 BXGT009327 Adenosine receptor A2a 135 reviewed G-protein coupled receptor
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P35498 BXGT009838 Sodium channel protein type 1 subunit alpha 6323 reviewed Ion channel
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P41229 BXGT010239 Lysine-specific demethylase 5C 8242 reviewed
P42262 BXGT010294 Glutamate receptor 2 2891 reviewed Ion channel
P42858 BXGT010341 Huntingtin 3064 reviewed
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P47869 BXGT010590 Gamma-aminobutyric acid receptor subunit alpha-2 2555 reviewed Ion channel
P48051 BXGT010611 G protein-activated inward rectifier potassium channel 2 3763 reviewed Ion channel
P48058 BXGT010614 Glutamate receptor 4 2893 reviewed Ion channel
P49419 BXGT010705 Alpha-aminoadipic semialdehyde dehydrogenase 501 reviewed Enzyme
P49711 BXGT010728 Transcriptional repressor CTCF 10664 reviewed Transcription factor
P50135 BXGT010776 Histamine N-methyltransferase 3176 reviewed
P50897 BXGT010823 Palmitoyl-protein thioesterase 1 5538 reviewed Enzyme
P50993 BXGT010826 Sodium/potassium-transporting ATPase subunit alpha-2 477 reviewed Transporter
P51531 BXGT010851 Probable global transcription activator SNF2L2 6595 reviewed Epigenetic regulator
P51572 BXGT010859 B-cell receptor-associated protein 31 10134 reviewed Transporter
P51649 BXGT010872 Succinate-semialdehyde dehydrogenase, mitochondrial 7915 reviewed Enzyme
P51688 BXGT010883 N-sulphoglucosamine sulphohydrolase 6448 reviewed Enzyme
P52788 BXGT010953 Spermine synthase 6611 reviewed
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P54762 BXGT011076 Ephrin type-B receptor 1 2047 reviewed Kinase
P54829 BXGT011085 Tyrosine-protein phosphatase non-receptor type 5 84867 reviewed
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P62258 BXGT011415 14-3-3 protein epsilon 7531 reviewed Chaperone
P63027 BXGT011487 Vesicle-associated membrane protein 2 6844 reviewed
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q00610 BXGT012539 Clathrin heavy chain 1 1213 reviewed Transporter
Q00975 BXGT012558 Voltage-dependent N-type calcium channel subunit alpha-1B 774 reviewed Ion channel
Q01668 BXGT012605 Voltage-dependent L-type calcium channel subunit alpha-1D 776 reviewed Ion channel
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q03468 BXGT012716 DNA excision repair protein ERCC-6 2074 reviewed
Q05586 BXGT012826 Glutamate receptor ionotropic, NMDA 1 2902 reviewed Ion channel
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q09472 BXGT013038 Histone acetyltransferase p300 2033 reviewed
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q12791 BXGT013264 Calcium-activated potassium channel subunit alpha-1 3778 reviewed Ion channel
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q13144 BXGT013317 Translation initiation factor eIF-2B subunit epsilon 8893 reviewed
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13363 BXGT013344 C-terminal-binding protein 1 1487 reviewed Transcription factor
Q13554 BXGT013374 Calcium/calmodulin-dependent protein kinase type II subunit beta 816 reviewed Kinase
Q14416 BXGT013468 Metabotropic glutamate receptor 2 2912 reviewed G-protein coupled receptor
Q14643 BXGT013493 Inositol 1,4,5-trisphosphate receptor type 1 3708 reviewed Ion channel
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q71U36 BXGT016705 Tubulin alpha-1A chain 7846 reviewed Cellular structure
Q8N4E7 BXGT018511 Ferritin, mitochondrial 94033 reviewed Storage
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8TD30 BXGT018805 Alanine aminotransferase 2 84706 reviewed Enzyme
Q8WXF7 BXGT019011 Atlastin-1 51062 reviewed Enzyme modulator
Q92796 BXGT019376 Disks large homolog 3 1741 reviewed
Q96FE5 BXGT019657 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 84894 reviewed Receptor
Q96IV0 BXGT019677 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase 55768 reviewed Enzyme
Q96RQ3 BXGT019732 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial 56922 reviewed Enzyme
Q96T60 BXGT019745 Bifunctional polynucleotide phosphatase/kinase 11284 reviewed
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha 6326 reviewed Ion channel
Q99497 BXGT019926 Protein/nucleic acid deglycase DJ-1 11315 reviewed Enzyme
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 3028 reviewed Enzyme
Q99798 BXGT019962 Aconitate hydratase, mitochondrial 50 reviewed Enzyme
Q9BPX6 BXGT020104 Calcium uptake protein 1, mitochondrial 10367 reviewed Calcium-binding protein
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9BZ23 BXGT020194 Pantothenate kinase 2, mitochondrial 80025 reviewed Kinase
Q9H4W6 BXGT020478 Transcription factor COE3 253738 reviewed
Q9HA77 BXGT020504 Probable cysteine--tRNA ligase, mitochondrial 79587 reviewed Enzyme
Q9HCC0 BXGT020530 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial 64087 reviewed Enzyme
Q9HD26 BXGT020540 Golgi-associated PDZ and coiled-coil motif-containing protein 57120 reviewed
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9NZJ4 BXGT021274 Sacsin 26278 reviewed
Q9P2R7 BXGT021304 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial 8803 reviewed Enzyme
Q9UBM7 BXGT021657 7-dehydrocholesterol reductase 1717 reviewed Enzyme
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha 815 reviewed Kinase
Q9Y233 BXGT022210 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 10846 reviewed
Q9Y2I2 BXGT022236 Netrin-G1 22854 reviewed Enzyme modulator
Q9Y4I1 BXGT022278 Unconventional myosin-Va 4644 reviewed Cellular structure
Q9Y4U1 BXGT022285 Methylmalonic aciduria and homocystinuria type C protein 25974 reviewed
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q99748 BXGT023217 Neurturin 4902 reviewed Signaling
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
Q9H2S1 BXGT023455 Small conductance calcium-activated potassium channel protein 2 3781 reviewed Ion channel
Q9UBP0 BXGT023601 Spastin 6683 reviewed Cellular structure
Q59FF6 BXGT023693 Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant 2074 unreviewed
P35670 BXGT023695 Copper-transporting ATPase 2 540 reviewed Transporter
A6NGN9 BXGT023893 IgLON family member 5 402665 reviewed
O95399 BXGT024237 Urotensin-2 10911 reviewed
Q9UNE7 BXGT025000 E3 ubiquitin-protein ligase CHIP 10273 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q96DA2 BXGT025522 Ras-related protein Rab-39B 116442 reviewed
Q05086 BXGT025648 Ubiquitin-protein ligase E3A 7337 reviewed
Q6IQ55 BXGT025689 Tau-tubulin kinase 2 146057 reviewed Kinase
P09471 BXGT026153 Guanine nucleotide-binding protein G(o) subunit alpha 2775 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease