Showing entry for 1-acylglycerol-3-phosphate O-acyltransferase ABHD5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018985
Protein Name1-acylglycerol-3-phosphate O-acyltransferase ABHD5
Uniport IdQ8WTS1
GeneABHD5
Gene Id51099
DomainAbhydrolase_1
Pfam PF00561  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.2 Endocrine system hsa04923 Regulation of lipolysis in adipocytes
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030154 cell differentiation
Biological Process GO:0006631 fatty acid metabolic process
Biological Process GO:0055088 lipid homeostasis
Biological Process GO:0010891 negative regulation of sequestering of triglyceride
Biological Process GO:0006654 phosphatidic acid biosynthetic process
Biological Process GO:0051006 positive regulation of lipoprotein lipase activity
Biological Process GO:0010898 positive regulation of triglyceride catabolic process
molecular function GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity
molecular function GO:0052689 carboxylic ester hydrolase activity
molecular function GO:0042171 lysophosphatidic acid acyltransferase activity
cellular component GO:0005829 cytosol
cellular component GO:0005811 lipid droplet
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-163560 Triglyceride catabolism
R-HSA-556833 Metabolism of lipids
R-HSA-8979227 Triglyceride metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011175 BXGD000701 Dehydration Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0011606 BXGD000735 Exfoliative dermatitis Skin and Connective Tissue Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013592 BXGD000857 Ectropion Eye Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0020757 BXGD001466 Ichthyoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0020758 BXGD001467 Congenital ichthyosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0033626 BXGD002412 Protein Deficiency Nutritional and Metabolic Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0039075 BXGD002788 Syndactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0079154 BXGD003065 Congenital Nonbullous Ichthyosiform Erythroderma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0152423 BXGD003587 Congenital small ears Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Otorhinolaryngologic Diseases
C0205682 BXGD004105 Waist-Hip Ratio
C0234146 BXGD004626 Absent reflex Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235259 BXGD004735 Subcapsular cataract Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0267812 BXGD005780 Micronodular cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0267971 BXGD005798 Storage disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0268238 BXGD005862 Triglyceride storage disease with ichthyosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0302142 BXGD006831 Deformity Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0311394 BXGD006884 Difficulty walking Pathological Conditions, Signs and Symptoms
C0342788 BXGD007552 Renal carnitine transport defect Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
C0349588 BXGD007933 Short stature
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0427063 BXGD008602 Shoulder girdle weakness
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0557874 BXGD009444 Global developmental delay
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0850715 BXGD010907 Abnormality of blood and blood-forming tissues
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1299579 BXGD012261 Early cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1806780 BXGD013759 Increased CSF protein
C1836156 BXGD014085 Progressive proximal muscle weakness
C1842680 BXGD014529 Small earlobe
C1848701 BXGD014967 Elevated hepatic transaminase
C1853136 BXGD015305 Neutral Lipid Storage Disease with Myopathy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C1853246 BXGD015323 Eversion of lower lip
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C3277687 BXGD018717 Central nervous system degeneration
C3550430 BXGD019135 Eclabion
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4020730 BXGD020473 Increased intramyocellular lipid droplets
C4021726 BXGD020735 EMG: myopathic abnormalities Musculoskeletal Diseases; Nervous System Diseases
C4551567 BXGD023355 Abnormal granulocyte morphology
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005982 Curcumin 368.38
BXGC0024988 Nifedipine 346.12
BXGC0037718 Ethacrynic Acid 302.01
BXGC0044200 Menadione 172.05
BXGC0046510 Tpck 351.07
BXGC0049858 Chalcone 208.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein