adisease

Showing entry for Ichthyoses

General Disease Information
BXGD Id	BXGD001466
Disease Name	Ichthyoses
Disease CUI Id	C0020757
MeSH Codes	C16 C17
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001574
Human Phenotype Ontology Term	Abnormality of the integument
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00204	BXGT003893	Sulfotransferase family cytosolic 2B member 1	6820	reviewed
O14832	BXGT004104	Phytanoyl-CoA dioxygenase, peroxisomal	5264	reviewed
O43175	BXGT004575	D-3-phosphoglycerate dehydrogenase	26227	reviewed	Enzyme
O60240	BXGT004860	Perilipin-1	5346	reviewed
O95470	BXGT005382	Sphingosine-1-phosphate lyase 1	8879	reviewed
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P02533	BXGT005887	Keratin, type I cytoskeletal 14	3861	reviewed
P02538	BXGT005888	Keratin, type II cytoskeletal 6A	3853	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02765	BXGT005952	Alpha-2-HS-glycoprotein	197	reviewed	Enzyme modulator
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04264	BXGT006176	Keratin, type II cytoskeletal 1	3848	reviewed
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P08779	BXGT006824	Keratin, type I cytoskeletal 16	3868	reviewed
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P13645	BXGT007936	Keratin, type I cytoskeletal 10	3858	reviewed
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15924	BXGT008171	Desmoplakin	1832	reviewed	Cellular structure
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18564	BXGT008414	Integrin beta-6	3694	reviewed	Receptor
P19961	BXGT008535	Alpha-amylase 2B	280	reviewed
P20591	BXGT008586	Interferon-induced GTP-binding protein Mx1	4599	reviewed	Enzyme modulator
P20930	BXGT008616	Filaggrin	2312	reviewed	Cellular structure
P26639	BXGT009122	Threonine--tRNA ligase, cytoplasmic	6897	reviewed	Enzyme
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P29400	BXGT009343	Collagen alpha-5(IV) chain	1287	reviewed
P35908	BXGT009878	Keratin, type II cytoskeletal 2 epidermal	3849	reviewed
P36507	BXGT009923	Dual specificity mitogen-activated protein kinase kinase 2	5605	reviewed	Kinase
P50542	BXGT010808	Peroxisomal targeting signal 1 receptor	5830	reviewed	Transporter
P54132	BXGT011032	Bloom syndrome protein	641	reviewed
P61011	BXGT011346	Signal recognition particle 54 kDa protein	6729	reviewed	Nucleic acid binding
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q06520	BXGT012880	Bile salt sulfotransferase	6822	reviewed
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q08623	BXGT012994	Pseudouridine-5'-phosphatase	8226	reviewed	Enzyme
Q13586	BXGT013380	Stromal interaction molecule 1	6786	reviewed
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q16828	BXGT013676	Dual specificity protein phosphatase 6	1848	reviewed
Q16881	BXGT013688	Thioredoxin reductase 1, cytoplasmic	7296	reviewed	Enzyme
Q8IYB8	BXGT018365	ATP-dependent RNA helicase SUPV3L1, mitochondrial	6832	reviewed
Q8N0W4	BXGT018492	Neuroligin-4, X-linked	57502	reviewed
Q8NBK3	BXGT018538	Formylglycine-generating enzyme	285362	reviewed
Q8TD19	BXGT018804	Serine/threonine-protein kinase Nek9	91754	reviewed	Kinase
Q8WTS1	BXGT018985	1-acylglycerol-3-phosphate O-acyltransferase ABHD5	51099	reviewed
Q96D31	BXGT019635	Calcium release-activated calcium channel protein 1	84876	reviewed	Ion channel
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9H8P0	BXGT020497	Polyprenol reductase	79644	reviewed
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9Y259	BXGT022219	Choline/ethanolamine kinase	1120	reviewed	Kinase
Q9Y5Y6	BXGT022308	Suppressor of tumorigenicity 14 protein	6768	reviewed	Enzyme
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
Q14807	BXGT024966	Kinesin-like protein KIF22	3835	reviewed	Cellular structure
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}