Showing entry for Aryl-hydrocarbon-interacting protein-like 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021280
Protein NameAryl-hydrocarbon-interacting protein-like 1
Uniport IdQ9NZN9
GeneAIPL1
Gene Id23746
DomainFKBP_C
Pfam PF00254  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04934 Cushing syndrome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0007603 phototransduction, visible light
Biological Process GO:0018343 protein farnesylation
Biological Process GO:0022400 regulation of rhodopsin mediated signaling pathway
Biological Process GO:0001895 retina homeostasis
Biological Process GO:0007601 visual perception
molecular function GO:0001918 farnesylated protein binding
molecular function GO:0003755 peptidyl-prolyl cis-trans isomerase activity
molecular function GO:0051082 unfolded protein binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0001917 photoreceptor inner segment
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0009398 BXGD000604 Color vision defect Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0014065 BXGD000884 Congenital cerebral hernia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0022578 BXGD001557 Keratoconus Eye Diseases
C0026010 BXGD001886 Microphthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028077 BXGD002069 Nyctalopia Eye Diseases
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042798 BXGD003003 Low Vision Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0085636 BXGD003218 Photophobia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0087012 BXGD003318 Ataxia, Spinocerebellar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0154860 BXGD003752 Hereditary retinal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0162666 BXGD003967 Mitochondrial Encephalomyopathies Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0234632 BXGD004691 Reduced visual acuity Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0235095 BXGD004723 Visual field constriction Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0271388 BXGD006196 Pendular Nystagmus Eye Diseases; Nervous System Diseases
C0339525 BXGD007258 Autosomal dominant retinitis pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0339527 BXGD007260 Leber Congenital Amaurosis Eye Diseases
C0375206 BXGD007973 Hemiplegia/hemiparesis
C0410000 BXGD008406 Overlap syndrome Skin and Connective Tissue Diseases; Immune System Diseases
C0423421 BXGD008484 Atrophic macular change
C0456909 BXGD008883 Blindness Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0476397 BXGD008991 Electroretinogram abnormal
C0554970 BXGD009428 Pallor of optic disc
C0557874 BXGD009444 Global developmental delay
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0730290 BXGD009946 Cone Dystrophy Eye Diseases
C0730362 BXGD009961 Disorder of macula of retina Eye Diseases
C0854723 BXGD011026 Retinal Dystrophies Eye Diseases
C0917796 BXGD011408 Optic Atrophy, Hereditary, Leber Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Nervous System Diseases
C1285162 BXGD012167 Degenerative disorder Pathological Conditions, Signs and Symptoms
C1288283 BXGD012175 Atrophoderma maculatum Skin and Connective Tissue Diseases
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1845977 BXGD014769 X- linked recessive
C1854065 BXGD015379 LATE-ONSET RETINAL DEGENERATION (disorder) Eye Diseases
C1855676 BXGD015528 Aplasia/Hypoplasia of the cerebellar vermis
C1858386 BXGD015786 Leber Congenital Amaurosis 4 Eye Diseases
C1862475 BXGD016132 Abnormality of retinal pigmentation
C1879328 BXGD016573 Blindness both eyes NOS (disorder) Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C1998028 BXGD016865 Photoreceptor degeneration Eye Diseases
C2751763 BXGD017737 Retinitis Pigmentosa, Juvenile, Aipl1-Related Eye Diseases
C2751764 BXGD017738 CONE-ROD DYSTROPHY, AIPL1-RELATED (disorder) Eye Diseases
C2931258 BXGD017991 Amaurosis congenita of Leber, type 1 Eye Diseases
C2931387 BXGD018015 Leber congenital amaurosis, type 4 Eye Diseases
C3278975 BXGD018749 Attenuation of retinal blood vessels
C3489532 BXGD018934 Cone-Rod Dystrophy 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C3665346 BXGD019278 Unspecified visual loss Pathological Conditions, Signs and Symptoms; Eye Diseases
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3808249 BXGD019541 Abnormality of the optic disc
C4021570 BXGD020678 Undetectable light- and dark-adapted electroretinogram
C4085590 BXGD022119 Cone-Rod Dystrophies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4277690 BXGD022377 Ciliopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C4551714 BXGD023398 Rod-Cone Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4703439 BXGD023647 Abnormality of fundus pigmentation
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004266 2-Propanol 60.1
BXGC0030612 tetraethylene glycol 194.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein