Showing entry for Ataxia, Spinocerebellar


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003318
Disease NameAtaxia, Spinocerebellar
Disease CUI IdC0087012
MeSH Codes C16   C10  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00142 BXGT003883 Thymidine kinase 2, mitochondrial 7084 reviewed Kinase
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O43280 BXGT004582 Trehalase 11181 reviewed
O43424 BXGT004592 Glutamate receptor ionotropic, delta-2 2895 reviewed Ion channel
O43497 BXGT004596 Voltage-dependent T-type calcium channel subunit alpha-1G 8913 reviewed Ion channel
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O95551 BXGT005384 Tyrosyl-DNA phosphodiesterase 2 51567 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00488 BXGT005552 Coagulation factor XIII A chain 2162 reviewed Enzyme
P00846 BXGT005674 ATP synthase subunit a 4508 reviewed Transporter
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P04156 BXGT006156 Major prion protein 5621 reviewed
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05129 BXGT006322 Protein kinase C gamma type 5582 reviewed Kinase
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P07384 BXGT006619 Calpain-1 catalytic subunit 823 reviewed Enzyme
P08034 BXGT006716 Gap junction beta-1 protein 2705 reviewed Cell-cell junction
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P11387 BXGT007696 DNA topoisomerase 1 7150 reviewed Enzyme
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P15374 BXGT008113 Ubiquitin carboxyl-terminal hydrolase isozyme L3 7347 reviewed Enzyme
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P22557 BXGT008783 5-aminolevulinate synthase, erythroid-specific, mitochondrial 212 reviewed Enzyme
P22612 BXGT008785 cAMP-dependent protein kinase catalytic subunit gamma 5568 reviewed Kinase
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42858 BXGT010341 Huntingtin 3064 reviewed
P43080 BXGT010354 Guanylyl cyclase-activating protein 1 2978 reviewed
P49638 BXGT010720 Alpha-tocopherol transfer protein 7274 reviewed Transporter
P49917 BXGT010765 DNA ligase 4 3981 reviewed
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
Q00532 BXGT012532 Cyclin-dependent kinase-like 1 8814 reviewed Kinase
Q04760 BXGT012782 Lactoylglutathione lyase 2739 reviewed
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q09470 BXGT013037 Potassium voltage-gated channel subfamily A member 1 3736 reviewed Ion channel
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q13255 BXGT013332 Metabotropic glutamate receptor 1 2911 reviewed G-protein coupled receptor
Q14003 BXGT013434 Potassium voltage-gated channel subfamily C member 3 3748 reviewed Ion channel
Q14643 BXGT013493 Inositol 1,4,5-trisphosphate receptor type 1 3708 reviewed Ion channel
Q14671 BXGT013496 Pumilio homolog 1 9698 reviewed Nucleic acid binding
Q16595 BXGT013643 Frataxin, mitochondrial 2395 reviewed Enzyme
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q6P2Q9 BXGT016446 Pre-mRNA-processing-splicing factor 8 10594 reviewed Nucleic acid binding
Q7Z2E3 BXGT017246 Aprataxin 54840 reviewed Nucleic acid binding
Q8NBK3 BXGT018538 Formylglycine-generating enzyme 285362 reviewed
Q8NI60 BXGT018572 Atypical kinase COQ8A, mitochondrial 56997 reviewed Kinase
Q8WVQ1 BXGT018996 Soluble calcium-activated nucleotidase 1 124583 reviewed
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q96T60 BXGT019745 Bifunctional polynucleotide phosphatase/kinase 11284 reviewed
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9GZZ9 BXGT020430 Ubiquitin-like modifier-activating enzyme 5 79876 reviewed Enzyme
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 55775 reviewed Enzyme
Q9NW15 BXGT021229 Anoctamin-10 55129 reviewed
Q9NZN9 BXGT021280 Aryl-hydrocarbon-interacting protein-like 1 23746 reviewed Chaperone
Q9UK17 BXGT021735 Potassium voltage-gated channel subfamily D member 3 3752 reviewed Ion channel
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q9NYP7 BXGT022661 Elongation of very long chain fatty acids protein 5 60481 reviewed Enzyme
Q9Y5W7 BXGT022783 Sorting nexin-14 57231 reviewed Enzyme modulator
O60502 BXGT023392 Protein O-GlcNAcase 10724 reviewed
Q96I25 BXGT024184 Splicing factor 45 84991 reviewed Nucleic acid binding
P16104 BXGT024571 Histone H2AX 3014 reviewed Nucleic acid binding
Q9UNE7 BXGT025000 E3 ubiquitin-protein ligase CHIP 10273 reviewed
Q9Y4W6 BXGT025025 AFG3-like protein 2 10939 reviewed Enzyme
Q6IQ55 BXGT025689 Tau-tubulin kinase 2 146057 reviewed Kinase
Q8IZL9 BXGT026139 Cyclin-dependent kinase 20 23552 reviewed Kinase
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease