acompound

Showing entry for Cerebroside

General Compound Information
BXGC Id	BXGC0003364
Compound Name	Cerebroside
Structure
Formula	C18H37NO2
InchiKey	WWUZIQQURGPMPG-KRWOKUGFSA-N
SMILES	[H]\C(CCCCCCCCCCCCC)=C(\[H])[C@@]([H])(O)[C@@]([H])(N)CO
Inchi	InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1
IUPAC	(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol
Molecular Weight	299.49
Pubchem Id	5280335
Chembl Id	CHEMBL67166

Targets of Information Source

DrugBank

DB03203

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Q9NZD2	BXGT021270	Glycolipid transfer protein	reviewed	Transporter	GLTP	experimental	-
P03300	BXGT006039	Genome polyprotein	reviewed	-	-	experimental	-
P03303	BXGT006041	Genome polyprotein	reviewed	-	-	experimental	-
P13900	BXGT007964	Genome polyprotein	reviewed	-	-	experimental	-
P03302	BXGT006040	Genome polyprotein	reviewed	-	-	experimental	-
P15151	BXGT008089	Poliovirus receptor	reviewed	-	PVR	experimental	-

PDB

SQS

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Q9NYA1	BXGT021254	Sphingosine kinase 1	reviewed	SPHK1	Kinase	-	-	-	-

Binding DB

83205

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT007576	Streptokinase A	reviewed		ska	-	-	-	150000
reviewed	BXGT011358	Ubiquitin-conjugating enzyme E2 N	reviewed		UBE2N	-	6425	-	-
reviewed	BXGT011358	Ubiquitin-conjugating enzyme E2 N	reviewed		UBE2N	-	6200	-	-
reviewed	BXGT012931	Bcl-2-related protein A1	reviewed		Bcl2a1	-	>20000	-	-
reviewed	BXGT010880	C-C chemokine receptor type 6	reviewed	G-protein coupled receptor	CCR6	-	20900	-	-
reviewed	BXGT009829	Apelin receptor	reviewed	G-protein coupled receptor	APLNR	-	>66600	-	-
reviewed	BXGT011600	Protein kinase C beta type	reviewed		Prkcb	-	57000	-	-
reviewed	BXGT007727	Cholesteryl ester transfer protein	reviewed		CETP	-	11500	-	-
reviewed	BXGT009205	cAMP-dependent protein kinase catalytic subunit alpha	reviewed		Prkaca	-	98	-	-

CHEMBL

CHEMBL67166

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P04062	BXGT006140	Lysosomal acid glucosylceramidase	reviewed	-	GBA	Potency	-	2818	nM
P09217	BXGT006872	Protein kinase C zeta type	reviewed	-	Prkcz	IC50	'='	23400	nM
Q9WTQ0	BXGT021929	Protein kinase C theta type	reviewed	-	Prkcq	IC50	'='	23400	nM
Q64617	BXGT016127	Protein kinase C eta type	reviewed	-	Prkch	IC50	'='	23400	nM
P09215	BXGT006870	Protein kinase C delta type	reviewed	-	Prkcd	IC50	'='	23400	nM
P63319	BXGT011518	Protein kinase C gamma type	reviewed	-	Prkcg	IC50	'='	23400	nM
P09216	BXGT006871	Protein kinase C epsilon type	reviewed	-	Prkce	IC50	'='	23400	nM
P68403	BXGT011600	Protein kinase C beta type	reviewed	-	Prkcb	IC50	'='	23400	nM
P05696	BXGT006379	Protein kinase C alpha type	reviewed	-	Prkca	IC50	'='	23400	nM
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	reviewed	-	IDH1	Potency	-	29092	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	443	/s/M
O94782	BXGT005332	Ubiquitin carboxyl-terminal hydrolase 1	reviewed	Enzyme	USP1	Potency	-	44668	nM
P35414	BXGT009829	Apelin receptor	reviewed	G-protein coupled receptor	APLNR	IC50	'>'	66600	nM
P61088	BXGT011358	Ubiquitin-conjugating enzyme E2 N	reviewed	-	UBE2N	IC50	'='	6425	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	200000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	460000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	170000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	600	/s/M
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	reviewed	-	KMT2A	Potency	'='	7943	nM
O00255	BXGT003903	Menin	reviewed	-	MEN1	Potency	'='	7943	nM
P10828	BXGT007624	Thyroid hormone receptor beta	reviewed	Nuclear receptor	THRB	Potency	'='	631	nM
P02545	BXGT005889	Prelamin-A/C	reviewed	-	LMNA	Potency	'='	5011	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	435	/s/M
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	527	/s/M
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	542	/s/M
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	418	/s/M
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	279	/s/M
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	580	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	680000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	660	/s/M
P06746	BXGT006496	DNA polymerase beta	reviewed	Enzyme	POLB	Potency	'='	35481	nM
P0A6C1	BXGT007045	Endonuclease 4	reviewed	-	nfo	Potency	'='	15848	nM
P02791	BXGT005965	Ferritin light chain	reviewed	-	FTL	Potency	'='	25118	nM
P09217	BXGT006872	Protein kinase C zeta type	reviewed	-	Prkcz	IC50	'='	6700	nM
Q9WTQ0	BXGT021929	Protein kinase C theta type	reviewed	-	Prkcq	IC50	'='	6700	nM
Q64617	BXGT016127	Protein kinase C eta type	reviewed	-	Prkch	IC50	'='	6700	nM
P09215	BXGT006870	Protein kinase C delta type	reviewed	-	Prkcd	IC50	'='	6700	nM
P63319	BXGT011518	Protein kinase C gamma type	reviewed	-	Prkcg	IC50	'='	6700	nM
P09216	BXGT006871	Protein kinase C epsilon type	reviewed	-	Prkce	IC50	'='	6700	nM
P68403	BXGT011600	Protein kinase C beta type	reviewed	-	Prkcb	IC50	'='	6700	nM
P05696	BXGT006379	Protein kinase C alpha type	reviewed	-	Prkca	IC50	'='	6700	nM
Q13951	BXGT013407	Core-binding factor subunit beta	reviewed	-	CBFB	Potency	-	39810	nM
Q01196	BXGT012575	Runt-related transcription factor 1	reviewed	Transcription factor	RUNX1	Potency	-	39810	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	1636	nM
P51684	BXGT010880	C-C chemokine receptor type 6	reviewed	G-protein coupled receptor	CCR6	IC50	'='	20900	nM
P09217	BXGT006872	Protein kinase C zeta type	reviewed	-	Prkcz	IC50	'='	40000	nM
Q9WTQ0	BXGT021929	Protein kinase C theta type	reviewed	-	Prkcq	IC50	'='	40000	nM
Q64617	BXGT016127	Protein kinase C eta type	reviewed	-	Prkch	IC50	'='	40000	nM
P09215	BXGT006870	Protein kinase C delta type	reviewed	-	Prkcd	IC50	'='	40000	nM
P63319	BXGT011518	Protein kinase C gamma type	reviewed	-	Prkcg	IC50	'='	40000	nM
P09216	BXGT006871	Protein kinase C epsilon type	reviewed	-	Prkce	IC50	'='	40000	nM
P68403	BXGT011600	Protein kinase C beta type	reviewed	-	Prkcb	IC50	'='	40000	nM
P05696	BXGT006379	Protein kinase C alpha type	reviewed	-	Prkca	IC50	'='	40000	nM
Q9NYA1	BXGT021254	Sphingosine kinase 1	reviewed	Kinase	SPHK1	Activity	'='	100	%
Q9NRA0	BXGT021183	Sphingosine kinase 2	reviewed	Kinase	SPHK2	Activity	'='	100	%
P63319	BXGT011518	Protein kinase C gamma type	reviewed	-	Prkcg	IC50	'='	57000	nM
P68403	BXGT011600	Protein kinase C beta type	reviewed	-	Prkcb	IC50	'='	57000	nM
P05696	BXGT006379	Protein kinase C alpha type	reviewed	-	Prkca	IC50	'='	57000	nM
P06280	BXGT006433	Alpha-galactosidase A	reviewed	-	GLA	Potency	'='	4466	nM
P54132	BXGT011032	Bloom syndrome protein	reviewed	-	BLM	Potency	'='	44668	nM
P04062	BXGT006140	Lysosomal acid glucosylceramidase	reviewed	-	GBA	Potency	-	12589	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	180000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	222	/s/M
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	1600000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	500000	nM
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	14125	nM
P02545	BXGT005889	Prelamin-A/C	reviewed	-	LMNA	Potency	'='	25118	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	870000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	490000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	846	/s/M
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	490	/s/M
P11597	BXGT007727	Cholesteryl ester transfer protein	reviewed	-	CETP	IC50	'='	11500	nM
P32302	BXGT009619	C-X-C chemokine receptor type 5	reviewed	G-protein coupled receptor	CXCR5	IC50	'='	32494	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	353	/s/M
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	407	/s/M
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	Kinase	MAPK1	Potency	'='	22387	nM
Q9NYA1	BXGT021254	Sphingosine kinase 1	reviewed	Kinase	SPHK1	IC50	'='	3860	nM
Q9NRA0	BXGT021183	Sphingosine kinase 2	reviewed	Kinase	SPHK2	IC50	'='	1560	nM
P10520	BXGT007576	Streptokinase A	reviewed	-	ska	EC50	'>'	150000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	-	-	-
P10636	BXGT007596	Microtubule-associated protein tau	reviewed	-	MAPT	Potency	'='	39810	nM
Q9UNA4	BXGT021785	DNA polymerase iota	reviewed	-	POLI	Potency	-	89125	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	9200	nM
P17405	BXGT008304	Sphingomyelin phosphodiesterase	reviewed	Enzyme	SMPD1	Potency	-	70794	nM
P61088	BXGT011358	Ubiquitin-conjugating enzyme E2 N	reviewed	-	UBE2N	IC50	'='	6200	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	11582	nM
P04062	BXGT006140	Lysosomal acid glucosylceramidase	reviewed	-	GBA	Potency	-	25118	nM
P10520	BXGT007576	Streptokinase A	reviewed	-	ska	EC50	'='	2560	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	810000	nM
P09217	BXGT006872	Protein kinase C zeta type	reviewed	-	Prkcz	IC50	'='	23000	nM
Q9WTQ0	BXGT021929	Protein kinase C theta type	reviewed	-	Prkcq	IC50	'='	23000	nM
Q64617	BXGT016127	Protein kinase C eta type	reviewed	-	Prkch	IC50	'='	23000	nM
P09215	BXGT006870	Protein kinase C delta type	reviewed	-	Prkcd	IC50	'='	23000	nM
P63319	BXGT011518	Protein kinase C gamma type	reviewed	-	Prkcg	IC50	'='	23000	nM
P09216	BXGT006871	Protein kinase C epsilon type	reviewed	-	Prkce	IC50	'='	23000	nM
P68403	BXGT011600	Protein kinase C beta type	reviewed	-	Prkcb	IC50	'='	23000	nM
P05696	BXGT006379	Protein kinase C alpha type	reviewed	-	Prkca	IC50	'='	23000	nM
P27791	BXGT009205	cAMP-dependent protein kinase catalytic subunit alpha	reviewed	-	Prkaca	IC50	'='	98	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	'='	15848	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	16360	nM
Q9F4F7	BXGT020344	4'-phosphopantetheinyl transferase ffp	reviewed	-	ffp	Potency	'='	79432	nM
P25779	BXGT009067	Cruzipain	reviewed	-		Potency	'='	31622	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	29092	nM
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	Potency	-	35481	nM
P11473	BXGT007709	Vitamin D3 receptor	reviewed	Nuclear receptor	VDR	Potency	-	56234	nM
Q07440	BXGT012931	Bcl-2-related protein A1	reviewed	-	Bcl2a1	IC50	'>'	20000	nM
P08659	BXGT006805	Luciferin 4-monooxygenase	reviewed	-		Potency	-	33807	nM
Q9Y253	BXGT022216	DNA polymerase eta	reviewed	-	POLH	Potency	-	35481	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat	'='	0	/s
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	130000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	480000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Km	'='	670000	nM
O33853	BXGT004464	Endoglycoceramidase II	unreviewed	-		Kcat/Km	'='	206	/s/M

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00081	Fig	Ficus carica	Fruits
BXGF00134	Common bean	Phaseolus vulgaris	Pulses
BXGF00151	Pomegranate	Punica granatum	Fruits
BXGF04889	Pogostemon cablin	Pogostemon cablin	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}