Showing entry for U6 snRNA phosphodiesterase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020107
Protein NameU6 snRNA phosphodiesterase
Uniport IdQ9BQ65
GeneUSB1
Gene Id79650
DomainHVSL
Pfam PF09749  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008380 RNA splicing
Biological Process GO:0034477 U6 snRNA 3'-end processing
molecular function GO:0000175 3'-5'-exoribonuclease activity
molecular function GO:1990838 poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends
cellular component GO:0045171 intercellular bridge
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0005741 BXGD000328 Blepharitis Eye Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009763 BXGD000628 Conjunctivitis Eye Diseases
C0011334 BXGD000716 Dental caries Stomatognathic Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0014866 BXGD000963 Esophageal Stenosis Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017574 BXGD001122 Gingivitis Infections; Stomatognathic Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020458 BXGD001393 Hyperhidrosis disorder Skin and Connective Tissue Diseases
C0020608 BXGD001443 Hypodontia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023532 BXGD001685 Leukoplakia, Oral Pathological Conditions, Signs and Symptoms; Neoplasms; Stomatognathic Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024523 BXGD001781 Malabsorption Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases
C0026985 BXGD001956 Myelodysplasia
C0027543 BXGD001997 Avascular necrosis of bone Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0032339 BXGD002352 Rothmund-Thomson syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037277 BXGD002677 Skin Diseases, Genetic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0037299 BXGD002685 Skin Ulcer Skin and Connective Tissue Diseases
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040588 BXGD002879 Tracheoesophageal Fistula Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Respiratory Tract Diseases
C0041974 BXGD002945 Urethral Stenosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0085660 BXGD003228 Aseptic necrosis Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0221260 BXGD004424 Dystrophia unguium Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0239804 BXGD004995 White hair
C0240310 BXGD005030 Hypoplasia of the maxilla
C0240444 BXGD005038 Pachyonychia Pathological Conditions, Signs and Symptoms
C0241005 BXGD005072 Creatine phosphokinase serum increased
C0263498 BXGD005316 Premature canities
C0265965 BXGD005592 Dyskeratosis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases
C0266039 BXGD005612 Taurodontism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0270685 BXGD006084 Cerebral calcification Nutritional and Metabolic Diseases; Nervous System Diseases
C0349588 BXGD007933 Short stature
C0392777 BXGD008068 Poikiloderma Pathological Conditions, Signs and Symptoms
C0427515 BXGD008619 Neutrophil abnormality
C0557874 BXGD009444 Global developmental delay
C0581354 BXGD009561 Recurrent sinusitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0694550 BXGD009852 Recurrent pneumonia Infections; Respiratory Tract Diseases
C0747085 BXGD010158 Recurrent otitis media Otorhinolaryngologic Diseases
C1301355 BXGD012287 Myelodysplastic-Myeloproliferative Diseases Hemic and Lymphatic Diseases
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1836735 BXGD014155 hypopigmented skin patch Skin and Connective Tissue Diseases
C1837770 BXGD014270 Sparse hair
C1842774 BXGD014536 Hypermelanotic macule
C1846821 BXGD014841 Abnormality of coagulation
C1853242 BXGD015322 Midface retrusion
C1855204 BXGD015472 Cellular immunodeficiency Immune System Diseases
C1855710 BXGD015534 Bone marrow hypocellularity
C1856749 BXGD015643 Aplastic/hypoplastic toenail
C1856954 BXGD015661 Plantar hyperkeratosis
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1858723 BXGD015823 Poikiloderma with Neutropenia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases
C1963165 BXGD016685 Malabsorption, CTCAE
C2132198 BXGD016930 Abnormal blistering of the skin
C2675111 BXGD017272 Abnormal eyelash morphology
C2919142 BXGD017867 Short Stature, CTCAE
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3495676 BXGD019000 Anorectal Malformations Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C3714745 BXGD019427 Malabsorption Digestive System Diseases
C3805574 BXGD019481 Increased fracture rate
C3806482 BXGD019514 Recurrent respiratory infections Infections; Respiratory Tract Diseases
C3814530 BXGD019668 Skin Vesicle Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C3887513 BXGD019887 Avascular necrosis Pathological Conditions, Signs and Symptoms
C4011556 BXGD020113 Abnormal eyebrow morphology
C4020958 BXGD020508 Rough bone trabeculation
C4022018 BXGD020872 Telangiectasia of the skin Cardiovascular Diseases
C4024737 BXGD021397 Aplasia/Hypoplasia of the skin
C4025838 BXGD021821 Abnormality of the pharynx
C4025900 BXGD021855 Abnormality of female internal genitalia
C4049767 BXGD021950 Infusion pump Alert priority PN
C4477095 BXGD022922 Increased lactate dehydrogenase activity
C4551675 BXGD023384 Keratoderma, Palmoplantar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C4553018 BXGD023532 Avascular Necrosis, CTCAE
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003418 Undylic acid 324.18
BXGC0003705 Chloride 35.45
BXGC0024261 Adenosine Phosphate 347.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein