Showing entry for 7-Amino-4-Hydroxynaphthalene-2-Sulfonic Acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0042336
Compound Name7-Amino-4-Hydroxynaphthalene-2-Sulfonic Acid
Structure
FormulaC10H9NO4S
InchiKeyKYARBIJYVGJZLB-UHFFFAOYSA-N
SMILESNc1ccc2c(c1)cc(cc2O)S(=O)(=O)O
InchiInChI=1S/C10H9NO4S/c11-7-1-2-9-6(3-7)4-8(5-10(9)12)16(13,14)15/h1-5,12H,11H2,(H,13,14,15)
IUPAC7-amino-4-hydroxynaphthalene-2-sulfonic acid
Molecular Weight239.03
Pubchem Id6868
Chembl IdCHEMBL220259
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50206424
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 reviewed PTPN11 - 1040 - -
reviewed BXGT011085 Tyrosine-protein phosphatase non-receptor type 5 reviewed PTPN5 - 33400 - -
reviewed BXGT010849 Dual specificity protein phosphatase 3 reviewed DUSP3 - 3430 - -
reviewed BXGT011085 Tyrosine-protein phosphatase non-receptor type 5 reviewed PTPN5 - >80000 - -
CHEMBL CHEMBL220259
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 14125 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 29092 nM
P39748 BXGT010134 Flap endonuclease 1 reviewed Enzyme FEN1 Potency - 8912 nM
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 56234 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 56234 nM
O75164 BXGT005104 Lysine-specific demethylase 4A reviewed - KDM4A Potency - 44668 nM
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial reviewed Enzyme GLS Potency - 3981 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 56234 nM
Q5VLE3 BXGT015884 RmtA unreviewed - rmtA IC50 '=' 590000 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 9200 nM
Q99873 BXGT019972 Protein arginine N-methyltransferase 1 reviewed Epigenetic regulator PRMT1 IC50 '=' 928000 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 22387 nM
P54829 BXGT011085 Tyrosine-protein phosphatase non-receptor type 5 reviewed - PTPN5 IC50 '=' 33400 nM
P55212 BXGT011112 Caspase-6 reviewed Enzyme CASP6 AC50 '=' 2150 nM
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 reviewed - PTPN11 IC50 '=' 1040 nM
P11940 BXGT007762 Polyadenylate-binding protein 1 reviewed - PABPC1 IC50 '>' 66000 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 79432 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 8912 nM
O95398 BXGT005378 Rap guanine nucleotide exchange factor 3 reviewed Enzyme modulator RAPGEF3 Potency - 31622 nM
O96028 BXGT005417 Histone-lysine N-methyltransferase NSD2 reviewed Epigenetic regulator NSD2 AC50 '=' 6490 nM
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 5623 nM
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short reviewed - GNAS Potency - 7079 nM
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic reviewed - IDH1 Potency - 52119 nM
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 reviewed - PIN1 Potency - 60119 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 5804 nM
P17405 BXGT008304 Sphingomyelin phosphodiesterase reviewed Enzyme SMPD1 Potency - 31622 nM
P11308 BXGT007684 Transcriptional regulator ERG reviewed Transcription factor ERG Potency - 11220 nM
P51449 BXGT010846 Nuclear receptor ROR-gamma reviewed Nuclear receptor RORC IC50 - 80000 nM
P07378 BXGT006616 Phosphoglycerate kinase, glycosomal reviewed - Potency - 14125 nM
P51452 BXGT010849 Dual specificity protein phosphatase 3 reviewed - DUSP3 IC50 '=' 3430 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 19952 nM
P43220 BXGT010367 Glucagon-like peptide 1 receptor reviewed G-protein coupled receptor GLP1R Potency - 12589 nM
O94782 BXGT005332 Ubiquitin carboxyl-terminal hydrolase 1 reviewed Enzyme USP1 Potency - 44668 nM
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 56234 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 56234 nM
P62826 BXGT011463 GTP-binding nuclear protein Ran reviewed Enzyme modulator RAN Potency - 56234 nM
P04608 BXGT006236 Protein Tat reviewed - tat IC50 - 47955 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00204 Common grape Vitis vinifera Fruits
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease