Showing entry for Catechin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0048389
Compound NameCatechin
Structure
FormulaC15H14O6
InchiKeyPFTAWBLQPZVEMU-UHFFFAOYSA-N
SMILESOc1cc2OC(c3ccc(c(c3)O)O)C(Cc2c(c1)O)O
InchiInChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2
IUPAC2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
Molecular Weight290.08
Pubchem Id1203
Chembl IdCHEMBL206452
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL206452
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Ki '=' 2420 nM
Q99N23 BXGT019994 Carbonic anhydrase 15 reviewed - Ca15 Ki '=' 7680 nM
O94782 BXGT005332 Ubiquitin carboxyl-terminal hydrolase 1 reviewed Enzyme USP1 Potency - 50118 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 11220 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 3162 nM
B4URF0 BXGT002146 Neuraminidase unreviewed - NA IC50 '>' 100000 nM
O97447 BXGT005436 Putative fructose-1,6-bisphosphate aldolase unreviewed - ald Potency '=' 9976 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 15848 nM
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 reviewed Enzyme CD38 IC50 '>' 100000 nM
P10415 BXGT007567 Apoptosis regulator Bcl-2 reviewed Signaling BCL2 Ki '>' 100000 nM
P04745 BXGT006255 Alpha-amylase 1 reviewed - AMY1A IC50 - - -
P04745 BXGT006255 Alpha-amylase 1 reviewed - AMY1A Inhibition '=' 13 %
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 14125 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 28183 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 28183 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency '=' 2511 nM
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase reviewed Enzyme PLA2G7 Activity - - -
P22748 BXGT008802 Carbonic anhydrase 4 reviewed - CA4 Ki '=' 4900 nM
Q9Y2D0 BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed - CA5B Ki '=' 4020 nM
P07265 BXGT006583 Alpha-glucosidase MAL62 reviewed - MAL62 logIC50 '=' 2 -
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 10000 nM
P07998 BXGT006711 Ribonuclease pancreatic reviewed - RNASE1 Ratio '=' 0 -
P07451 BXGT006627 Carbonic anhydrase 3 reviewed - CA3 Ki '=' 3580 nM
P35218 BXGT009796 Carbonic anhydrase 5A, mitochondrial reviewed - CA5A Ki '=' 4210 nM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki '=' 1840 nM
Q16790 BXGT013670 Carbonic anhydrase 9 reviewed - CA9 Ki '=' 5030 nM
Q8N1Q1 BXGT018499 Carbonic anhydrase 13 reviewed - CA13 Ki '=' 10510 nM
Q9ULX7 BXGT021769 Carbonic anhydrase 14 reviewed - CA14 Ki '=' 11550 nM
P23280 BXGT008844 Carbonic anhydrase 6 reviewed - CA6 Ki '=' 4910 nM
P16050 BXGT008184 Arachidonate 15-lipoxygenase reviewed Enzyme ALOX15 Potency '=' 12589 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Potency '=' 15848 nM
P43166 BXGT010364 Carbonic anhydrase 7 reviewed - CA7 Ki '=' 450 nM
O43570 BXGT004601 Carbonic anhydrase 12 reviewed - CA12 Ki '=' 4720 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency '=' 14125 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency '=' 141253 nM
P11064 BXGT007646 Low molecular weight phosphotyrosine protein phosphatase reviewed - ACP1 Inhibition '=' 14 %
P14916 BXGT008066 Urease subunit alpha reviewed - ureA IC50 '=' 13 ug.mL-1
P69996 BXGT011656 Urease subunit beta reviewed - ureB IC50 '=' 13 ug.mL-1
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 reviewed - PON1 Activity - - -
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 Activity '=' 0 pm/min/mg
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 3162 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 3162 nM
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 44668 nM
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 19952 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 35481 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00027 Chinese mustard Brassica juncea Vegetables
BXGF00050 Chinese cinnamon Cinnamomum aromaticum Herbs and Spices
BXGF00087 Sea-buckthornberry Hippophae rhamnoides Fruits
BXGF00118 Nutmeg Myristica fragrans Herbs and Spices
BXGF00142 Purslane Portulaca oleracea Herbs and Spices
BXGF00151 Pomegranate Punica granatum Fruits
BXGF00183 Common thyme Thymus vulgaris Herbs and Spices
BXGF00198 Adzuki bean Vigna angularis Pulses
BXGF00201 Climbing bean Vigna umbellata Pulses
BXGF00206 Ginger Zingiber officinale Herbs and Spices
BXGF00218 Longan Dimocarpus longan Fruits
BXGF00337 Ginkgo nuts Ginkgo biloba Herbs and Spices
BXGF00369 Sacred lotus Nelumbo nucifera Vegetables
BXGF00380 White mustard Sinapis alba Herbs and Spices
BXGF00886 Abutilon theophrasti Abutilon theophrasti Medicinal Plant
BXGF01031 Epimedium sagittatum Epimedium sagittatum Medicinal Plant
BXGF01036 Sargentodoxa cuneata Sargentodoxa cuneata Medicinal Plant
BXGF01074 Centella asiatica Centella asiatica Medicinal Plant
BXGF01126 Polygonum cuspidatum Polygonum cuspidatum Medicinal Plant
BXGF01185 Aloe vera Aloe vera Medicinal Plant
BXGF01283 Crataegus pinnatifida Crataegus pinnatifida Medicinal Plant
BXGF01325 Murraya exotica Murraya exotica Medicinal Plant
BXGF01357 Ampelopsis japonica Ampelopsis japonica Medicinal Plant
BXGF01443 Trachycarpus fortunei Trachycarpus fortunei Medicinal Plant
BXGF01506 Thymus quinquecostatus Thymus quinquecostatus Medicinal Plant
BXGF01597 Senegalia catechu Senegalia catechu Medicinal Plant
BXGF01609 Epimedium sempervirens Epimedium sempervirens Others
BXGF01721 Humulus lupulus Humulus lupulus Medicinal Plant
BXGF01743 Uncaria macrophylla Uncaria macrophylla Medicinal Plant
BXGF01767 Uncaria rhynchophylla Uncaria rhynchophylla Medicinal Plant
BXGF01823 Houttuynia cordata Houttuynia cordata Medicinal Plant
BXGF01868 Vitex negundo Vitex negundo Medicinal Plant
BXGF01896 Lilium brownii Lilium brownii Medicinal Plant
BXGF01900 Aloe ferox Aloe ferox Medicinal Plant
BXGF02204 Apocynum venetum Apocynum venetum Medicinal Plant
BXGF02214 Morus bombycis Morus bombycis Medicinal Plant
BXGF02359 Eucommia ulmoides Eucommia ulmoides Medicinal Plant
BXGF02370 Epimedium pubescens Epimedium pubescens Medicinal Plant
BXGF02604 Agrimonia pilosa Agrimonia pilosa Medicinal Plant
BXGF02612 Mosla chinensis Mosla chinensis Medicinal Plant
BXGF02642 Vigna umbeuata Vigna umbeuata Others
BXGF02786 Rubus coreanus Rubus coreanus Human Edible Plant
BXGF02881 Epimedium grandiflorum Epimedium grandiflorum Medicinal Plant
BXGF03110 Gleditsia sinensis Gleditsia sinensis Medicinal Plant
BXGF03158 Rheum officinale Rheum officinale Medicinal Plant
BXGF03243 Elsholtzia ciliata Elsholtzia ciliata Medicinal Plant
BXGF03398 Solanum nigrum Solanum nigrum Medicinal Plant
BXGF03426 Rhodiola crenulata Rhodiola crenulata Medicinal Plant
BXGF03488 Paeonia suffruticosa Paeonia suffruticosa Medicinal Plant
BXGF03583 Epimedium koreanum Epimedium koreanum Medicinal Plant
BXGF03610 Bistorta officinalis Bistorta officinalis Medicinal Plant
BXGF03766 Drynaria fortunei Drynaria fortunei Medicinal Plant
BXGF03965 Orostachys japonicus Orostachys japonicus Others
BXGF03988 Rheum coreanum Rheum coreanum Others
BXGF04053 Smilax china Smilax china Medicinal Plant
BXGF04062 Spatholobus suberectus Spatholobus suberectus Medicinal Plant
BXGF04064 Rumex japonicus Rumex japonicus Medicinal Plant
BXGF04080 Persicaria orientalis Persicaria orientalis Medicinal Plant
BXGF04194 Fagopyrum dibotrys Fagopyrum dibotrys Medicinal Plant
BXGF04200 Euphorbia hirta Euphorbia hirta Medicinal Plant
BXGF04209 Chaenomeles sinensis Chaenomeles sinensis Medicinal Plant
BXGF04224 Bistorta manshuriensis Bistorta manshuriensis Others
BXGF04235 Rubus chingii Rubus chingii Food Plant
BXGF04315 Orostachys fimbriata Orostachys fimbriata Others
BXGF04341 Sanguisorba officinalis Sanguisorba officinalis Medicinal Plant
BXGF04361 Cynomorium songaricum Cynomorium songaricum Medicinal Plant
BXGF04382 Murraya paniculata Murraya paniculata Medicinal Plant
BXGF04539 Rheum palmatum Rheum palmatum Medicinal Plant
BXGF04607 Morus alba Morus alba Medicinal Plant
BXGF04631 Aloe spicata Aloe spicata Medicinal Plant
BXGF04712 Prunus mume Prunus mume Medicinal Plant
BXGF04817 Euonymus alatus Euonymus alatus Medicinal Plant
BXGF04864 Uncaria sinensis Uncaria sinensis Medicinal Plant
BXGF04881 Fallopia multiflora Fallopia multiflora Medicinal Plant
BXGF04886 Boehmeria nivea Boehmeria nivea Medicinal Plant
BXGF04913 Acacia catechu Acacia catechu Medicinal Plant
BXGF04926 Aloe africana Aloe africana Medicinal Plant
BXGF05160 Chaenomeles speciosa Chaenomeles speciosa Medicinal Plant
BXGF05269 Hypericum perforatum Hypericum perforatum Medicinal Plant
BXGF05274 Lilium lancifolium Lilium lancifolium Medicinal Plant
BXGF05370 Epimedium brevicornu Epimedium brevicornu Others
BXGF05442 Zanthoxylum bungeanum Zanthoxylum bungeanum Medicinal Plant
BXGF05524 Rumex nepalensis Rumex nepalensis Medicinal Plant
BXGF05526 Salvia miltiorrhiza Salvia miltiorrhiza Medicinal Plant
BXGF05571 Ziziphus jujuba Ziziphus jujuba Medicinal Plant
BXGF05728 Persicaria perfoliata Persicaria perfoliata Medicinal Plant
BXGF05787 Smilax glabra Smilax glabra Medicinal Plant
BXGF05831 Rosa laevigata Rosa laevigata Medicinal Plant
BXGF05876 Gleditsia japonica Gleditsia japonica Medicinal Plant
BXGF05877 Rheum tanguticum Rheum tanguticum Medicinal Plant
BXGF05931 Lilium pumilum Lilium pumilum Medicinal Plant
BXGF06070 Perilla frutescens Perilla frutescens Medicinal Plant
BXGF06075 Zanthoxylum schinifolium Zanthoxylum schinifolium Medicinal Plant
BXGF06161 Epimedium wushanense Epimedium wushanense Medicinal Plant
BXGF06214 Uncaria gambir Uncaria gambir Medicinal Plant
BXGF06238 Gardenia jasminoides Gardenia jasminoides Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease