adisease

Showing entry for Marijuana Abuse

General Disease Information
BXGD Id	BXGD001808
Disease Name	Marijuana Abuse
Disease CUI Id	C0024809
MeSH Codes	C25 F03
Disease Class Name	Chemically-Induced Disorders; Mental Disorders
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:150
Disease Ontology Class Name	disease of mental health
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O00522	BXGT003935	Krev interaction trapped protein 1	889	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75334	BXGT005111	Liprin-alpha-2	8499	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00492	BXGT005556	Hypoxanthine-guanine phosphoribosyltransferase	3251	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05177	BXGT006336	Cytochrome P450 1A2	1544	reviewed	Enzyme
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	3350	reviewed	G-protein coupled receptor
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	1133	reviewed	G-protein coupled receptor
P09172	BXGT006865	Dopamine beta-hydroxylase	1621	reviewed
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P0DP23	BXGT007520	Calmodulin-1	808	reviewed
P0DP24	BXGT007521	Calmodulin-2	808	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P11308	BXGT007684	Transcriptional regulator ERG	2078	reviewed	Transcription factor
P11712	BXGT007738	Cytochrome P450 2C9	1559	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14616	BXGT008026	Insulin receptor-related protein	3645	reviewed	Kinase
P15104	BXGT008081	Glutamine synthetase	2752	reviewed	Enzyme
P15121	BXGT008083	Aldo-keto reductase family 1 member B1	231	reviewed	Enzyme
P16152	BXGT008201	Carbonyl reductase [NADPH] 1	873	reviewed
P16435	BXGT008226	NADPH--cytochrome P450 reductase	5447	reviewed
P18089	BXGT008379	Alpha-2B adrenergic receptor	151	reviewed	G-protein coupled receptor
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	1131	reviewed	G-protein coupled receptor
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21917	BXGT008707	D(4) dopamine receptor	1815	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22612	BXGT008785	cAMP-dependent protein kinase catalytic subunit gamma	5568	reviewed	Kinase
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P28329	BXGT009251	Choline O-acetyltransferase	1103	reviewed	Enzyme
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P30536	BXGT009435	Translocator protein	706	reviewed
P31391	BXGT009535	Somatostatin receptor type 4	6754	reviewed	G-protein coupled receptor
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P34972	BXGT009779	Cannabinoid receptor 2	1269	reviewed	G-protein coupled receptor
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P37268	BXGT009975	Squalene synthase	2222	reviewed
P41279	BXGT010254	Mitogen-activated protein kinase kinase kinase 8	1326	reviewed	Kinase
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	3357	reviewed	G-protein coupled receptor
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P49888	BXGT010756	Estrogen sulfotransferase	6783	reviewed
P50897	BXGT010823	Palmitoyl-protein thioesterase 1	5538	reviewed	Enzyme
P53041	BXGT010968	Serine/threonine-protein phosphatase 5	5536	reviewed
P55211	BXGT011111	Caspase-9	842	reviewed	Enzyme
Q00536	BXGT012535	Cyclin-dependent kinase 16	5127	reviewed	Kinase
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q09472	BXGT013038	Histone acetyltransferase p300	2033	reviewed
Q13554	BXGT013374	Calcium/calmodulin-dependent protein kinase type II subunit beta	816	reviewed	Kinase
Q14469	BXGT013473	Transcription factor HES-1	3280	reviewed	Transcription factor
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15257	BXGT013554	Serine/threonine-protein phosphatase 2A activator	5524	reviewed	Enzyme modulator
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q8NBP7	BXGT018541	Proprotein convertase subtilisin/kexin type 9	255738	reviewed	Enzyme
Q8NFD2	BXGT018559	Ankyrin repeat and protein kinase domain-containing protein 1	255239	reviewed	Kinase
Q96KB5	BXGT019685	Lymphokine-activated killer T-cell-originated protein kinase	55872	reviewed	Kinase
Q96Q40	BXGT019714	Cyclin-dependent kinase 15	65061	reviewed	Kinase
Q99558	BXGT019934	Mitogen-activated protein kinase kinase kinase 14	9020	reviewed	Kinase
Q9BY08	BXGT020177	Emopamil-binding protein-like	84650	reviewed	Enzyme
Q9BZ23	BXGT020194	Pantothenate kinase 2, mitochondrial	80025	reviewed	Kinase
Q9UKI8	BXGT021743	Serine/threonine-protein kinase tousled-like 1	9874	reviewed	Kinase
Q9UPZ9	BXGT021804	Serine/threonine-protein kinase ICK	22858	reviewed	Kinase
Q7Z624	BXGT022792	Calmodulin-lysine N-methyltransferase	79823	reviewed
Q9UGC6	BXGT023734	Regulator of G-protein signaling 17	26575	reviewed	Enzyme modulator
P0DP25	BXGT024595	Calmodulin-3	808	reviewed
P07320	BXGT026150	Gamma-crystallin D	1421	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}