Showing entry for Ectonucleotide pyrophosphatase/phosphodiesterase family member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008764
Protein NameEctonucleotide pyrophosphatase/phosphodiesterase family member 1
Uniport IdP22413
GeneENPP1
Gene Id5167
DomainEndonuclease_NS; Phosphodiest; Somatomedin_B
Pfam PF01223   PF01663   PF01033  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.4 Nucleotide metabolism hsa00240 Pyrimidine metabolism
1. Metabolism 1.1 Carbohydrate metabolism hsa00500 Starch and sucrose metabolism
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00740 Riboflavin metabolism
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00770 Pantothenate and CoA biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process
Biological Process GO:0046034 ATP metabolic process
Biological Process GO:0031214 biomineral tissue development
Biological Process GO:0030643 cellular phosphate ion homeostasis
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:0006091 generation of precursor metabolites and energy
Biological Process GO:0006955 immune response
Biological Process GO:0030505 inorganic diphosphate transport
Biological Process GO:0030318 melanocyte differentiation
Biological Process GO:0030502 negative regulation of bone mineralization
Biological Process GO:0030308 negative regulation of cell growth
Biological Process GO:0045599 negative regulation of fat cell differentiation
Biological Process GO:0046325 negative regulation of glucose import
Biological Process GO:0045719 negative regulation of glycogen biosynthetic process
Biological Process GO:1990787 negative regulation of hh target transcription factor activity
Biological Process GO:0046627 negative regulation of insulin receptor signaling pathway
Biological Process GO:0031953 negative regulation of protein autophosphorylation
Biological Process GO:0090305 nucleic acid phosphodiester bond hydrolysis
Biological Process GO:0009143 nucleoside triphosphate catabolic process
Biological Process GO:0006796 phosphate-containing compound metabolic process
Biological Process GO:0030500 regulation of bone mineralization
Biological Process GO:0006771 riboflavin metabolic process
Biological Process GO:0030730 sequestering of triglyceride
molecular function GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding
molecular function GO:0005524 ATP binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0106177 cyclic-GMP-AMP hydrolase activity
molecular function GO:0036218 dTTP diphosphatase activity
molecular function GO:0004527 exonuclease activity
molecular function GO:0005158 insulin receptor binding
molecular function GO:0035529 NADH pyrophosphatase activity
molecular function GO:0003676 nucleic acid binding
molecular function GO:0047429 nucleoside-triphosphate diphosphatase activity
molecular function GO:0004551 nucleotide diphosphatase activity
molecular function GO:0004528 phosphodiesterase I activity
molecular function GO:0030247 polysaccharide binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0005044 scavenger receptor activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0009986 cell surface
cellular component GO:0005615 extracellular space
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005765 lysosomal membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-196843 Vitamin B2 (riboflavin) metabolism
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-199220 Vitamin B5 (pantothenate) metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002962 BXGD000160 Angina Pectoris Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0002982 BXGD000163 Angioid Streaks Eye Diseases
C0003090 BXGD000175 Ankylosis Musculoskeletal Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003862 BXGD000230 Arthralgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0005395 BXGD000309 Bile Duct Diseases Digestive System Diseases
C0005890 BXGD000345 Body Height
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007196 BXGD000453 Restrictive cardiomyopathy Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007820 BXGD000491 Cerebrovascular Disorders Nervous System Diseases; Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0015230 BXGD000969 Exanthema Skin and Connective Tissue Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0017181 BXGD001103 Gastrointestinal Hemorrhage Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018777 BXGD001217 Conductive hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0020441 BXGD001384 Hypercementosis Stomatognathic Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0021655 BXGD001508 Insulin Resistance Nutritional and Metabolic Diseases
C0021670 BXGD001509 insulinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023221 BXGD001619 Leg Length Inequality Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0023443 BXGD001648 Hairy Cell Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024523 BXGD001781 Malabsorption Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0026267 BXGD001896 Mitral Valve Prolapse Syndrome Cardiovascular Diseases
C0026470 BXGD001903 Monoclonal Gammopathy of Undetermined Significance Immune System Diseases; Hemic and Lymphatic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027709 BXGD002026 Nephrocalcinosis Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028756 BXGD002083 Obesity, Morbid Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029422 BXGD002142 Osteochondrodysplasias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0029442 BXGD002151 Osteomalacia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases; Endocrine System Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029464 BXGD002161 Osteosclerosis Musculoskeletal Diseases
C0029882 BXGD002177 Otitis Media Otorhinolaryngologic Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0032463 BXGD002357 Polycythemia Vera Neoplasms; Hemic and Lymphatic Diseases
C0032914 BXGD002379 Pre-Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0033774 BXGD002419 Pruritus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0033802 BXGD002425 Pseudogout Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0033839 BXGD002434 Pseudorabies Infections; Nervous System Diseases; Animal Diseases
C0033847 BXGD002437 Pseudoxanthoma Elasticum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0035078 BXGD002505 Kidney Failure Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035317 BXGD002533 Retinal Hemorrhage Pathological Conditions, Signs and Symptoms; Eye Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0038449 BXGD002758 Stricture of artery Cardiovascular Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039494 BXGD002814 Temporomandibular Joint Disorders Musculoskeletal Diseases; Stomatognathic Diseases
C0042749 BXGD002998 Viremia Pathological Conditions, Signs and Symptoms; Infections
C0042769 BXGD002999 Virus Diseases Infections
C0085096 BXGD003123 Peripheral Vascular Diseases Cardiovascular Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085298 BXGD003155 Sudden Cardiac Death Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085682 BXGD003238 Hypophosphatemia Nutritional and Metabolic Diseases
C0149630 BXGD003334 Bicuspid aortic valve Cardiovascular Diseases
C0149721 BXGD003349 Left Ventricular Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151811 BXGD003478 Subcutaneous nodule Neoplasms; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0151825 BXGD003481 Bone pain Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0151854 BXGD003487 Abnormal platelets Hemic and Lymphatic Diseases
C0152459 BXGD003600 Linear atrophy Pathological Conditions, Signs and Symptoms
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0155477 BXGD003794 Tympanosclerosis involving other combination of structures Otorhinolaryngologic Diseases
C0155552 BXGD003801 Hearing Loss, Mixed Conductive-Sensorineural Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0157946 BXGD003873 Osteoarthrosis, localized, not specified whether primary or secondary Musculoskeletal Diseases
C0162323 BXGD003937 Polyarthritis Musculoskeletal Diseases
C0221270 BXGD004430 Acanthosis Pathological Conditions, Signs and Symptoms
C0235357 BXGD004742 Hypoplasia of teeth Digestive System Diseases; Stomatognathic Diseases
C0235394 BXGD004744 Wasting Nutritional and Metabolic Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0239137 BXGD004965 Coxa valga Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0239138 BXGD004966 Hip joint varus deformity - observation Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0239174 BXGD004969 Late tooth eruption
C0240635 BXGD005047 Byzanthine arch palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Stomatognathic Diseases
C0241074 BXGD005078 Hyperextensible skin
C0242292 BXGD005146 McCune-Albright Syndrome Musculoskeletal Diseases
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242490 BXGD005171 Enthesopathy Musculoskeletal Diseases; Wounds and Injuries
C0262361 BXGD005229 Growth abnormality
C0262621 BXGD005261 Abnormality of the sacroiliac joint
C0263746 BXGD005346 Osteoarthritis of the hand Musculoskeletal Diseases
C0263978 BXGD005356 Disorder of soft tissue Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0265329 BXGD005518 Organoid Nevus Phakomatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0268079 BXGD005812 Hyperphosphaturia Nutritional and Metabolic Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0270250 BXGD006072 Meconium peritonitis Digestive System Diseases; Infections
C0270685 BXGD006084 Cerebral calcification Nutritional and Metabolic Diseases; Nervous System Diseases
C0271185 BXGD006170 Metamorphopsia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0275544 BXGD006377 Congenital infectious disease Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infections
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282201 BXGD006799 Phosphate Diabetes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0282612 BXGD006820 Prostatic Intraepithelial Neoplasias Neoplasms
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0342642 BXGD007519 Autosomal dominant hypophosphatemic rickets Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases
C0342643 BXGD007520 Autosomal recessive hypophosphatemic vitamin D refractory rickets Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases
C0342649 BXGD007522 Vascular calcification Nutritional and Metabolic Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349588 BXGD007933 Short stature
C0375206 BXGD007973 Hemiplegia/hemiparesis
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0403477 BXGD008286 Medullary nephrocalcinosis Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0409952 BXGD008399 Idiopathic osteoarthritis Musculoskeletal Diseases
C0410528 BXGD008430 Skeletal dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0423798 BXGD008510 Increased tendency to bruise Wounds and Injuries
C0428791 BXGD008635 Aortic valve calcification Nutritional and Metabolic Diseases; Cardiovascular Diseases
C0473583 BXGD008946 Nevus elasticus Neoplasms
C0518988 BXGD009074 Dental abscess Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases; Stomatognathic Diseases
C0520739 BXGD009106 Hereditary pyropoikilocytosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0541764 BXGD009259 Delayed bone age
C0542514 BXGD009277 Blue sclera Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0544755 BXGD009310 Genu varum Musculoskeletal Diseases
C0553730 BXGD009417 Calcium pyrophosphate deposition disease Musculoskeletal Diseases
C0576093 BXGD009525 Knee joint valgus deformity Musculoskeletal Diseases
C0577631 BXGD009535 Carotid Atherosclerosis Nervous System Diseases; Cardiovascular Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0694533 BXGD009848 Moderate obesity
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C0733682 BXGD009968 Hypophosphatemic Rickets, X-Linked Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases
C0740277 BXGD009972 Bile duct carcinoma Digestive System Diseases; Neoplasms
C0745730 BXGD010132 Multiple lipomata Neoplasms
C0854078 BXGD010996 Diabetic end stage renal disease
C0856169 BXGD011096 Endothelial dysfunction
C0856830 BXGD011119 Calcium pyrophosphate arthropathy Musculoskeletal Diseases
C0858925 BXGD011199 Deafness labyrinthine Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0870082 BXGD011309 Hyperkeratosis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0948379 BXGD011533 Impaired insulin secretion
C0949691 BXGD011585 Spondylarthropathies Musculoskeletal Diseases
C1260873 BXGD011835 Aortic valve disorder Cardiovascular Diseases
C1282952 BXGD012153 Enthesitis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases; Wounds and Injuries
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1321865 BXGD012443 Juvenile astrocytoma Neoplasms
C1332183 BXGD012496 Adult Astrocytic Tumor Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1535939 BXGD013323 Pneumocystis jiroveci pneumonia Infections; Respiratory Tract Diseases
C1611184 BXGD013455 Calcification of coronary artery Nutritional and Metabolic Diseases; Cardiovascular Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1704375 BXGD013551 Hypophosphatemic Rickets Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1833323 BXGD013911 Rickets of the lower limbs Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C1833667 BXGD013937 Elevated alkaline phosphatase of bone origin
C1836940 BXGD014182 Thickened nuchal skin fold
C1837081 BXGD014193 Tibial bowing Musculoskeletal Diseases
C1838663 BXGD014335 Enlargement of the wrists
C1843921 BXGD014620 Postural instability Nervous System Diseases
C1845169 BXGD014724 Renal phosphate wasting
C1859727 BXGD015927 Arterial calcification of infancy Nutritional and Metabolic Diseases
C1859728 BXGD015928 Coronary Sclerosis, Medial, of Infancy Nutritional and Metabolic Diseases; Cardiovascular Diseases
C1860107 BXGD015954 Distal femoral bowing
C1861329 BXGD016033 Spinal canal stenosis Musculoskeletal Diseases
C1865343 BXGD016316 OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT OF SPINE Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C1956257 BXGD016623 Pulmonary Stenosis Cardiovascular Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1962966 BXGD016678 Retinopathy, CTCAE
C1963077 BXGD016680 Bone Pain, CTCAE 3.0
C1963165 BXGD016685 Malabsorption, CTCAE
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2362324 BXGD017091 Pediatric Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2750078 BXGD017649 Hypophosphatemic Rickets, Autosomal Recessive, 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C3178782 BXGD018536 Aortic Stiffness
C3279547 BXGD018759 Hypergranulosis
C3494419 BXGD018965 Dentofacial Deformities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C3536983 BXGD019078 Familial Hypophosphatemic Rickets Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases
C3536984 BXGD019079 Vitamin D-Resistant Rickets, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3540852 BXGD019094 Rickets, X-Linked Hypophosphatemic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases
C3553764 BXGD019187 Joint hyperflexibility
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3714619 BXGD019418 Insulin resistance syndrome Nutritional and Metabolic Diseases
C3714745 BXGD019427 Malabsorption Digestive System Diseases
C3809781 BXGD019612 Cole disease
C3887650 BXGD019911 Adult Rickets Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C3887892 BXGD019924 Aortic Valve Disease 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4020957 BXGD020507 Abnormal trabecular bone morphology
C4021028 BXGD020525 Pseudo-fractures
C4021662 BXGD020726 Abnormal endocardium morphology Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4021797 BXGD020787 Abnormality of the thorax
C4022001 BXGD020863 Abnormality of the cerebral vasculature
C4022018 BXGD020872 Telangiectasia of the skin Cardiovascular Diseases
C4022947 BXGD021043 Decreased resting energy expenditure
C4023065 BXGD021091 Low serum calcitriol
C4023579 BXGD021221 Abnormality of renal excretion
C4024631 BXGD021352 Renal hypophosphatemia Nutritional and Metabolic Diseases
C4024890 BXGD021458 Excessive wrinkled skin
C4025269 BXGD021612 Generalized arterial calcification
C4025320 BXGD021643 Craniofacial asymmetry Pathological Conditions, Signs and Symptoms
C4551675 BXGD023384 Keratoderma, Palmoplantar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C4551970 BXGD023457 Sclerotic vertebral endplates
C4551985 BXGD023465 ARTERIAL CALCIFICATION, GENERALIZED, OF INFANCY, 1 Nutritional and Metabolic Diseases
C4552243 BXGD023498 Dyschromatosis
C4553962 BXGD023553 Hyperkeratosis, CTCAE
C4554063 BXGD023559 Bone Pain, CTCAE 5.0
C4703554 BXGD023657 Increased waist to hip ratio
C4703555 BXGD023658 Decreased waist to hip ratio
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003993 Uridine diphosphate 404.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein