adisease

Showing entry for Polymyositis

General Disease Information
BXGD Id	BXGD003226
Disease Name	Polymyositis
Disease CUI Id	C0085655
MeSH Codes	C05 C10
Disease Class Name	Musculoskeletal Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O15553	BXGT004181	Pyrin	4210	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75923	BXGT005166	Dysferlin	8291	reviewed	Transporter
O95786	BXGT005396	Probable ATP-dependent RNA helicase DDX58	23586	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02144	BXGT005853	Myoglobin	4151	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05413	BXGT006355	Fatty acid-binding protein, heart	2170	reviewed
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09917	BXGT006941	Arachidonate 5-lipoxygenase	240	reviewed	Enzyme
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P12081	BXGT007772	Histidine--tRNA ligase, cytoplasmic	3035	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P21580	BXGT008666	Tumor necrosis factor alpha-induced protein 3	7128	reviewed	Enzyme
P21860	BXGT008698	Receptor tyrosine-protein kinase erbB-3	2065	reviewed	Kinase
P21980	BXGT008715	Protein-glutamine gamma-glutamyltransferase 2	7052	reviewed	Enzyme
P22749	BXGT008803	Granulysin	10578	reviewed
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P26951	BXGT009147	Interleukin-3 receptor subunit alpha	3563	reviewed	Signaling
P29597	BXGT009367	Non-receptor tyrosine-protein kinase TYK2	7297	reviewed	Kinase
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P33681	BXGT009739	T-lymphocyte activation antigen CD80	941	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35499	BXGT009839	Sodium channel protein type 4 subunit alpha	6329	reviewed	Ion channel
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P40189	BXGT010164	Interleukin-6 receptor subunit beta	3572	reviewed	Signaling
P40933	BXGT010209	Interleukin-15	3600	reviewed
P46939	BXGT010555	Utrophin	7402	reviewed
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P49913	BXGT010761	Cathelicidin antimicrobial peptide	820	reviewed
P51451	BXGT010848	Tyrosine-protein kinase Blk	640	reviewed	Kinase
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
Q01780	BXGT012614	Exosome component 10	5394	reviewed
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13231	BXGT013329	Chitotriosidase-1	1118	reviewed
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q15046	BXGT013527	Lysine--tRNA ligase	3735	reviewed	Enzyme
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15796	BXGT013599	Mothers against decapentaplegic homolog 2	4087	reviewed	Transcription factor
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q16658	BXGT013651	Fascin	6624	reviewed	Cellular structure
Q8WTT0	BXGT018987	C-type lectin domain family 4 member C	170482	reviewed	Receptor
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9HBE5	BXGT020518	Interleukin-21 receptor	50615	reviewed	Receptor
Q9NPH2	BXGT021158	Inositol-3-phosphate synthase 1	51477	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9UHX1	BXGT021707	Poly(U)-binding-splicing factor PUF60	22827	reviewed
Q9UJ71	BXGT021725	C-type lectin domain family 4 member K	50489	reviewed	Receptor
Q9UKV8	BXGT021752	Protein argonaute-2	27161	reviewed
Q9UPN9	BXGT021799	E3 ubiquitin-protein ligase TRIM33	51592	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y3B4	BXGT022255	Splicing factor 3B subunit 6	51639	reviewed
Q96C86	BXGT022803	m7GpppX diphosphatase	28960	reviewed	Enzyme
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P35523	BXGT023831	Chloride channel protein 1	1180	reviewed	Ion channel
Q96MS0	BXGT025241	Roundabout homolog 3	64221	reviewed	Receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}