Showing entry for Docosahexaenoic acid omega-hydroxylase CYP4F3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT026164
Protein NameDocosahexaenoic acid omega-hydroxylase CYP4F3
Uniport IdQ08477
GeneCYP4F3
Gene Id4051
Domainp450
Pfam PF00067  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00590 Arachidonic acid metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019369 arachidonic acid metabolic process
Biological Process GO:0006690 icosanoid metabolic process
Biological Process GO:0036101 leukotriene B4 catabolic process
Biological Process GO:0006691 leukotriene metabolic process
Biological Process GO:0042361 menaquinone catabolic process
Biological Process GO:0042376 phylloquinone catabolic process
Biological Process GO:0042377 vitamin K catabolic process
molecular function GO:0008391 arachidonic acid monooxygenase activity
molecular function GO:0070330 aromatase activity
molecular function GO:0020037 heme binding
molecular function GO:0005506 iron ion binding
molecular function GO:0050051 leukotriene-B4 20-monooxygenase activity
molecular function GO:0004497 monooxygenase activity
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-211859 Biological oxidations
R-HSA-211897 Cytochrome P450 - arranged by substrate type
R-HSA-211935 Fatty acids
R-HSA-211945 Phase I - Functionalization of compounds
R-HSA-211958 Miscellaneous substrates
R-HSA-211979 Eicosanoids
R-HSA-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)
R-HSA-2142753 Arachidonic acid metabolism
R-HSA-556833 Metabolism of lipids
R-HSA-8978868 Fatty acid metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001175 BXGD000029 Acquired Immunodeficiency Syndrome Infections; Immune System Diseases
C0001624 BXGD000067 Adrenal Gland Neoplasms Neoplasms; Endocrine System Diseases
C0001627 BXGD000068 Congenital adrenal hyperplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0011195 BXGD000702 Dejerine-Sottas Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020071 BXGD001356 Hereditary Sensory Autonomic Neuropathy, Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022665 BXGD001573 Kidney Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024537 BXGD001786 Malaria, Vivax Infections
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038644 BXGD002776 Sudden infant death syndrome Pathological Conditions, Signs and Symptoms
C0041296 BXGD002903 Tuberculosis Infections
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042769 BXGD002999 Virus Diseases Infections
C0085580 BXGD003191 Essential Hypertension Cardiovascular Diseases
C0085762 BXGD003251 Alcohol abuse Chemically-Induced Disorders; Mental Disorders
C0149896 BXGD003382 Primary gout Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0162565 BXGD003957 Acute intermittent porphyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0162836 BXGD003990 Hidradenitis Suppurativa Infections; Skin and Connective Tissue Diseases
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0206667 BXGD004228 Adrenal Cortical Adenoma Neoplasms; Endocrine System Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0221271 BXGD004431 Elastosis perforans serpiginosa Skin and Connective Tissue Diseases
C0234133 BXGD004624 Extrapyramidal sign
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0268287 BXGD005884 Deficiency of steroid 21-monooxygenase Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0278877 BXGD006608 Adult Meningioma Neoplasms; Nervous System Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0342474 BXGD007485 Lipoid congenital adrenal hyperplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392702 BXGD008065 Abnormal involuntary movement Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0427086 BXGD008605 Involuntary Movements Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0520905 BXGD009122 Vomiting, Postoperative Pathological Conditions, Signs and Symptoms
C0523465 BXGD009209 Serum albumin measurement
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0596321 BXGD009642 Chemical Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686347 BXGD009832 Tardive Dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0856169 BXGD011096 Endothelial dysfunction
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1302401 BXGD012303 Adenoma of large intestine Digestive System Diseases; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1333763 BXGD012640 Gastric Cardia Carcinoma
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1384514 BXGD012940 Conn Syndrome Endocrine System Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1762616 BXGD013753 Meningioma, benign, no ICD-O subtype Neoplasms; Nervous System Diseases
C1853230 BXGD015317 Aphakia, congenital primary Eye Diseases
C1868684 BXGD016527 EAR, PATELLA, SHORT STATURE SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2931379 BXGD018012 Neonatal Torulopsis glabrata Fungemia Infections
C2939465 BXGD018182 Deficiency of glucose-6-phosphate dehydrogenase Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3150911 BXGD018356 GASTRIC CANCER, INTESTINAL
C3714760 BXGD019432 Drug-induced tardive dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4282128 BXGD022420 PATENT DUCTUS ARTERIOSUS 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4329212 BXGD022783 17-Alpha-Hydroxylase/17,20 Lyase Deficiency
C4529962 BXGD023178 Fatty Liver Disease
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0041820 Schisantherin E 538.22
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein