Showing entry for Mastocytosis, Systemic


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004363
Disease NameMastocytosis, Systemic
Disease CUI IdC0221013
MeSH Codes C04   C20  
Disease Class NameNeoplasms; Immune System Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14638 BXGT004077 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 5169 reviewed Enzyme
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O14936 BXGT004114 Peripheral plasma membrane protein CASK 8573 reviewed Kinase
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O60462 BXGT004876 Neuropilin-2 8828 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75030 BXGT005096 Microphthalmia-associated transcription factor 4286 reviewed
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06729 BXGT006486 T-cell surface antigen CD2 914 reviewed
P06734 BXGT006491 Low affinity immunoglobulin epsilon Fc receptor 2208 reviewed Receptor
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P08700 BXGT006816 Interleukin-3 3562 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10909 BXGT007630 Clusterin 1191 reviewed
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P16070 BXGT008186 CD44 antigen 960 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P17405 BXGT008304 Sphingomyelin phosphodiesterase 6609 reviewed Enzyme
P19113 BXGT008458 Histidine decarboxylase 3067 reviewed
P21583 BXGT008667 Kit ligand 4254 reviewed
P22681 BXGT008795 E3 ubiquitin-protein ligase CBL 867 reviewed Enzyme
P26951 BXGT009147 Interleukin-3 receptor subunit alpha 3563 reviewed Signaling
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P28908 BXGT009302 Tumor necrosis factor receptor superfamily member 8 943 reviewed
P29350 BXGT009335 Tyrosine-protein phosphatase non-receptor type 6 5777 reviewed
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32320 BXGT009622 Cytidine deaminase 978 reviewed Enzyme
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
Q01081 BXGT012566 Splicing factor U2AF 35 kDa subunit 7307 reviewed
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q08722 BXGT013002 Leukocyte surface antigen CD47 961 reviewed
Q13237 BXGT013331 cGMP-dependent protein kinase 2 5593 reviewed Kinase
Q13951 BXGT013407 Core-binding factor subunit beta 865 reviewed
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q6ZN17 BXGT016631 Protein lin-28 homolog B 389421 reviewed
Q8WXI8 BXGT019014 C-type lectin domain family 4 member D 338339 reviewed
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q99497 BXGT019926 Protein/nucleic acid deglycase DJ-1 11315 reviewed Enzyme
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
P20138 BXGT023857 Myeloid cell surface antigen CD33 945 reviewed Receptor
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
P31358 BXGT025061 CAMPATH-1 antigen 1043 reviewed
Q99435 BXGT025240 Protein kinase C-binding protein NELL2 4753 reviewed Calcium-binding protein
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease