Showing entry for Cholestasis of pregnancy


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD005896
Disease NameCholestasis of pregnancy
Disease CUI IdC0268318
MeSH Codes C06   C13  
Disease Class NameDigestive System Diseases; Female Urogenital Diseases and Pregnancy Complications
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O95342 BXGT005373 Bile salt export pump 8647 reviewed Transporter
O95750 BXGT005395 Fibroblast growth factor 19 9965 reviewed Signaling
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P05231 BXGT006345 Interleukin-6 3569 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P10301 BXGT007556 Ras-related protein R-Ras 6237 reviewed Enzyme modulator
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P21439 BXGT008649 Phosphatidylcholine translocator ABCB4 5244 reviewed Transporter
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P30041 BXGT009393 Peroxiredoxin-6 9588 reviewed Enzyme
P30559 BXGT009442 Oxytocin receptor 5021 reviewed G-protein coupled receptor
P31391 BXGT009535 Somatostatin receptor type 4 6754 reviewed G-protein coupled receptor
P34998 BXGT009781 Corticotropin-releasing factor receptor 1 1394 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P46721 BXGT010536 Solute carrier organic anion transporter family member 1A2 6579 reviewed Transporter
P47869 BXGT010590 Gamma-aminobutyric acid receptor subunit alpha-2 2555 reviewed Ion channel
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
Q13219 BXGT013327 Pappalysin-1 5069 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14671 BXGT013496 Pumilio homolog 1 9698 reviewed Nucleic acid binding
Q14973 BXGT013515 Sodium/bile acid cotransporter 6554 reviewed Transporter
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15078 BXGT013534 Cyclin-dependent kinase 5 activator 1 8851 reviewed Enzyme modulator
Q15185 BXGT013549 Prostaglandin E synthase 3 10728 reviewed Chaperone
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q86Z14 BXGT017639 Beta-klotho 152831 reviewed Enzyme
Q8TDU6 BXGT018814 G-protein coupled bile acid receptor 1 151306 reviewed G-protein coupled receptor
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q9BVG8 BXGT020144 Kinesin-like protein KIFC3 3801 reviewed Cellular structure
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 10599 reviewed Transporter
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P30040 BXGT023417 Endoplasmic reticulum resident protein 29 10961 reviewed Transporter
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease