adisease

General Disease Information
BXGD Id	BXGD007344
Disease Name	Familial primary pulmonary hypertension
Disease CUI Id	C0340543
MeSH Codes	C08
Disease Class Name	Respiratory Tract Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P05231	BXGT006345	Interleukin-6	3569	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P12931	BXGT007859	Proto-oncogene tyrosine-protein kinase Src	6714	reviewed	Kinase
P21333	BXGT008638	Filamin-A	2316	reviewed
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P37023	BXGT009953	Serine/threonine-protein kinase receptor R3	94	reviewed	Kinase
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P69892	BXGT011647	Hemoglobin subunit gamma-2	3048	reviewed
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13547	BXGT013373	Histone deacetylase 1	3065	reviewed	Epigenetic regulator
Q13873	BXGT013398	Bone morphogenetic protein receptor type-2	659	reviewed	Kinase
Q9P2K8	BXGT021302	eIF-2-alpha kinase GCN2	440275	reviewed
Q9UQL6	BXGT021813	Histone deacetylase 5	10014	reviewed	Epigenetic regulator
Q9UK05	BXGT023094	Growth/differentiation factor 2	2658	reviewed	Signaling
O15198	BXGT024049	Mothers against decapentaplegic homolog 9	4093	reviewed	Transcription factor
O14649	BXGT025486	Potassium channel subfamily K member 3	3777	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}