Showing entry for Granulomatosis with polyangiitis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD019004
Disease NameGranulomatosis with polyangiitis
Disease CUI IdC3495801
MeSH Codes C08   C20   C14  
Disease Class NameRespiratory Tract Diseases; Immune System Diseases; Cardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O15054 BXGT004121 Lysine-specific demethylase 6B 23135 reviewed Epigenetic regulator
O43143 BXGT004571 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 1665 reviewed Enzyme
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O75369 BXGT005119 Filamin-B 2317 reviewed
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01031 BXGT005720 Complement C5 727 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02724 BXGT005934 Glycophorin-A 2993 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06280 BXGT006433 Alpha-galactosidase A 2717 reviewed
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P08185 BXGT006742 Corticosteroid-binding globulin 866 reviewed Enzyme modulator
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21730 BXGT008687 C5a anaphylatoxin chemotactic receptor 1 728 reviewed G-protein coupled receptor
P22087 BXGT008729 rRNA 2'-O-methyltransferase fibrillarin 2091 reviewed Enzyme
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P24158 BXGT008951 Myeloblastin 5657 reviewed Enzyme
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28676 BXGT009284 Grancalcin 25801 reviewed
P28702 BXGT009287 Retinoic acid receptor RXR-beta 6257 reviewed Nuclear receptor
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31151 BXGT009510 Protein S100-A7 6278 reviewed Calcium-binding protein
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P43489 BXGT010394 Tumor necrosis factor receptor superfamily member 4 7293 reviewed
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P53634 BXGT011007 Dipeptidyl peptidase 1 1075 reviewed Enzyme
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P60022 BXGT011285 Beta-defensin 1 1672 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P99999 BXGT012235 Cytochrome c 54205 reviewed
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q12918 BXGT013280 Killer cell lectin-like receptor subfamily B member 1 3820 reviewed
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9H227 BXGT020447 Cytosolic beta-glucosidase 57733 reviewed Enzyme
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P20036 BXGT022764 HLA class II histocompatibility antigen, DP alpha 1 chain 3113 reviewed Immune response
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P29590 BXGT024350 Protein PML 5371 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease