Showing entry for Luminal B Breast Carcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD019245
Disease NameLuminal B Breast Carcinoma
Disease CUI IdC3642346
MeSH Codes   
Disease Class Name
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14745 BXGT004090 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 9368 reviewed
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial 2744 reviewed Enzyme
O95931 BXGT005407 Chromobox protein homolog 7 23492 reviewed Epigenetic regulator
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11177 BXGT007666 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial 5162 reviewed
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P46063 BXGT010501 ATP-dependent DNA helicase Q1 5965 reviewed Enzyme
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P51677 BXGT010876 C-C chemokine receptor type 3 1232 reviewed G-protein coupled receptor
P54886 BXGT011092 Delta-1-pyrroline-5-carboxylate synthase 5832 reviewed Enzyme
P57735 BXGT011214 Ras-related protein Rab-25 57111 reviewed
Q12797 BXGT013266 Aspartyl/asparaginyl beta-hydroxylase 444 reviewed
Q13233 BXGT013330 Mitogen-activated protein kinase kinase kinase 1 4214 reviewed Kinase
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase 9833 reviewed Kinase
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16853 BXGT013683 Membrane primary amine oxidase 8639 reviewed
Q5NUL3 BXGT015621 Free fatty acid receptor 4 338557 reviewed
Q96GD0 BXGT019665 Pyridoxal phosphate phosphatase 57026 reviewed Enzyme
Q99728 BXGT019956 BRCA1-associated RING domain protein 1 580 reviewed
Q9HCU9 BXGT020539 Breast cancer metastasis-suppressor 1 25855 reviewed
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q6ZMT1 BXGT023758 SH3 and cysteine-rich domain-containing protein 2 342667 reviewed
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q14566 BXGT025969 DNA replication licensing factor MCM6 4175 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease