Showing entry for GRN-related frontotemporal dementia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD019664
Disease NameGRN-related frontotemporal dementia
Disease CUI IdC3811918
MeSH Codes C18   C10   F03  
Disease Class NameNutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00311 BXGT003908 Cell division cycle 7-related protein kinase 8317 reviewed Kinase
O15409 BXGT004166 Forkhead box protein P2 93986 reviewed
O43612 BXGT004605 Orexin 3060 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01034 BXGT005721 Cystatin-C 1471 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P04156 BXGT006156 Major prion protein 5621 reviewed
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P07602 BXGT006646 Prosaposin 5660 reviewed
P07737 BXGT006663 Profilin-1 5216 reviewed
P09651 BXGT006913 Heterogeneous nuclear ribonucleoprotein A1 3178 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17516 BXGT008313 Aldo-keto reductase family 1 member C4 1109 reviewed Enzyme
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P31350 BXGT009526 Ribonucleoside-diphosphate reductase subunit M2 6241 reviewed Enzyme
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P45985 BXGT010496 Dual specificity mitogen-activated protein kinase kinase 4 6416 reviewed Kinase
P49711 BXGT010728 Transcriptional repressor CTCF 10664 reviewed Transcription factor
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49810 BXGT010747 Presenilin-2 5664 reviewed Enzyme
P52758 BXGT010951 2-iminobutanoate/2-iminopropanoate deaminase 10247 reviewed
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P60953 BXGT011342 Cell division control protein 42 homolog 998 reviewed Enzyme modulator
P78330 BXGT011833 Phosphoserine phosphatase 5723 reviewed Enzyme
P80075 BXGT011876 C-C motif chemokine 8 6355 reviewed Signaling
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13283 BXGT013334 Ras GTPase-activating protein-binding protein 1 10146 reviewed Nucleic acid binding
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5300 reviewed
Q15118 BXGT013540 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 5163 reviewed Kinase
Q15366 BXGT013559 Poly(rC)-binding protein 2 5094 reviewed Enzyme
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 10280 reviewed
Q99933 BXGT019976 BAG family molecular chaperone regulator 1 573 reviewed
Q9NZ09 BXGT021267 Ubiquitin-associated protein 1 51271 reviewed
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q9Y4P1 BXGT022283 Cysteine protease ATG4B 23192 reviewed Enzyme
P35232 BXGT022663 Prohibitin 5245 reviewed
Q9NVA2 BXGT025757 Septin-11 55752 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease