Showing entry for Serine/threonine-protein kinase 36


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021192
Protein NameSerine/threonine-protein kinase 36
Uniport IdQ9NRP7
GeneSTK36
Gene Id27148
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007420 brain development
Biological Process GO:0060271 cilium assembly
Biological Process GO:0003351 epithelial cilium movement involved in extracellular fluid movement
Biological Process GO:0007228 positive regulation of hh target transcription factor activity
Biological Process GO:0045880 positive regulation of smoothened signaling pathway
Biological Process GO:0009791 post-embryonic development
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0051090 regulation of DNA-binding transcription factor activity
Biological Process GO:0007224 smoothened signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0008134 transcription factor binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005576 extracellular region
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000786 BXGD000010 Spontaneous abortion Female Urogenital Diseases and Pregnancy Complications
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004144 BXGD000259 Atelectasis Respiratory Tract Diseases
C0006267 BXGD000383 Bronchiectasis Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0008677 BXGD000560 Bronchitis, Chronic Infections; Respiratory Tract Diseases
C0009080 BXGD000580 Clubbed Fingers Musculoskeletal Diseases
C0010036 BXGD000642 Corneal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0010200 BXGD000653 Coughing Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0016842 BXGD001083 Congenital pectus excavatum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0018520 BXGD001197 Halitosis Pathological Conditions, Signs and Symptoms
C0018681 BXGD001214 Headache Pathological Conditions, Signs and Symptoms
C0018777 BXGD001217 Conductive hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018935 BXGD001252 Hematocrit procedure
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0021359 BXGD001498 Infertility Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022521 BXGD001549 Kartagener Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases; Cardiovascular Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0029883 BXGD002178 Otitis Media with Effusion Otorhinolaryngologic Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032987 BXGD002386 Ectopic Pregnancy Female Urogenital Diseases and Pregnancy Complications
C0035455 BXGD002554 Rhinitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0149516 BXGD003324 Chronic sinusitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0231835 BXGD004527 Tachypnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0271441 BXGD006203 Chronic otitis media Otorhinolaryngologic Diseases
C0403823 BXGD008315 Asthenozoospermia Male Urogenital Diseases
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0476273 BXGD008986 Respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0518015 BXGD009068 Hemoglobin measurement
C0600031 BXGD009681 Congenital absence of spleen Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Hemic and Lymphatic Diseases
C0600260 BXGD009701 Lung Diseases, Obstructive Respiratory Tract Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1335177 BXGD012771 Ovarian Serous Adenocarcinoma Neoplasms
C1531647 BXGD013301 Cerebral ventriculomegaly Nervous System Diseases
C1855672 BXGD015527 Immotile cilia
C3179349 BXGD018550 Gastrointestinal Stromal Sarcoma Digestive System Diseases; Neoplasms
C3278923 BXGD018748 Dilated ventricles (finding)
C3806482 BXGD019514 Recurrent respiratory infections Infections; Respiratory Tract Diseases
C4317124 BXGD022728 Polynesian Bronchiectasis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases; Cardiovascular Diseases
C4551493 BXGD023318 Situs inversus totalis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4551720 BXGD023400 Primary Ciliary Dyskinesia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C4551906 BXGD023439 Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases; Cardiovascular Diseases
C4703436 BXGD023646 Impaired nasal mucociliary clearance
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein