Showing entry for Lysosomal Pro-X carboxypeptidase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010338
Protein NameLysosomal Pro-X carboxypeptidase
Uniport IdP42785
GenePRCP
Gene Id5547
DomainPeptidase_S28
Pfam PF05577  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.2 Endocrine system hsa04614 Renin-angiotensin system
5. Organismal Systems 5.4 Digestive system hsa04974 Protein digestion and absorption
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060055 angiogenesis involved in wound healing
Biological Process GO:0007597 blood coagulation, intrinsic pathway
Biological Process GO:0097009 energy homeostasis
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0003085 negative regulation of systemic arterial blood pressure
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0002353 plasma kallikrein-kinin cascade
Biological Process GO:0006508 proteolysis
Biological Process GO:0043535 regulation of blood vessel endothelial cell migration
Biological Process GO:2000377 regulation of reactive oxygen species metabolic process
Biological Process GO:0002155 regulation of thyroid hormone mediated signaling pathway
molecular function GO:0008239 dipeptidyl-peptidase activity
molecular function GO:0004185 serine-type carboxypeptidase activity
cellular component GO:0035577 azurophil granule membrane
cellular component GO:0045178 basal part of cell
cellular component GO:0070062 extracellular exosome
cellular component GO:0101003 ficolin-1-rich granule membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-140837 Intrinsic Pathway of Fibrin Clot Formation
R-HSA-140877 Formation of Fibrin Clot (Clotting Cascade)
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001175 BXGD000029 Acquired Immunodeficiency Syndrome Infections; Immune System Diseases
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003175 BXGD000187 Anthrax disease Infections
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0008031 BXGD000511 Chest Pain Pathological Conditions, Signs and Symptoms
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0020256 BXGD001370 Congenital Hydrocephalus Nervous System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027404 BXGD001984 Narcolepsy Nervous System Diseases; Mental Disorders
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0031382 BXGD002301 PHENCYCLIDINE/ARYLCYCLOHEXYLAMINE ABUSE
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032326 BXGD002351 Pneumothorax Respiratory Tract Diseases
C0032914 BXGD002379 Pre-Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0034067 BXGD002456 Pulmonary Emphysema Respiratory Tract Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0037090 BXGD002665 Signs and Symptoms, Respiratory Pathological Conditions, Signs and Symptoms
C0040425 BXGD002863 Tonsillitis Infections; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0080178 BXGD003107 Spina Bifida Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0085580 BXGD003191 Essential Hypertension Cardiovascular Diseases
C0152426 BXGD003589 Craniorachischisis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0242510 BXGD005173 Drug usage Chemically-Induced Disorders; Mental Disorders
C0265101 BXGD005454 Carotid artery occlusion Nervous System Diseases; Cardiovascular Diseases
C0275524 BXGD006376 Coinfection Infections
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0349566 BXGD007928 Squamous cell carcinoma of tongue Neoplasms; Stomatognathic Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0398625 BXGD008203 Protein C Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0431128 BXGD008664 Papillary craniopharyngioma Neoplasms
C0497169 BXGD009054 hiv-infection/aids Infections
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0584960 BXGD009579 Factor V Leiden mutation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0742132 BXGD010057 cervical cancer metastasis
C0851886 BXGD010929 Pneumocystis Infections Infections
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1535939 BXGD013323 Pneumocystis jiroveci pneumonia Infections; Respiratory Tract Diseases
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C2363741 BXGD017100 HIV-1 infection
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2985280 BXGD018223 Blood Protein Measurement
C3496069 BXGD019017 cocaine use
C4048329 BXGD021904 Immunosuppression
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012888 2-Methyl-3,4-Dihydro-1H-Isoquinoline 147.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein