adisease

Showing entry for Pre-Eclampsia

General Disease Information
BXGD Id	BXGD002379
Disease Name	Pre-Eclampsia
Disease CUI Id	C0032914
MeSH Codes	C13
Disease Class Name	Female Urogenital Diseases and Pregnancy Complications
Semantic Type	Pathologic Function
Human Phenotype Ontology Id	HP:0001197
Human Phenotype Ontology Term	Abnormality of prenatal development or birth
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O43772	BXGT004623	Mitochondrial carnitine/acylcarnitine carrier protein	788	reviewed	Transporter
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75530	BXGT005135	Polycomb protein EED	8726	reviewed
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	8654	reviewed
O95865	BXGT005404	N(G),N(G)-dimethylarginine dimethylaminohydrolase 2	23564	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05156	BXGT006329	Complement factor I	3426	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05546	BXGT006367	Heparin cofactor 2	3053	reviewed	Enzyme modulator
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07099	BXGT006546	Epoxide hydrolase 1	2052	reviewed
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P08476	BXGT006774	Inhibin beta A chain	3624	reviewed	Signaling
P08603	BXGT006798	Complement factor H	3075	reviewed
P08758	BXGT006821	Annexin A5	308	reviewed
P08833	BXGT006827	Insulin-like growth factor-binding protein 1	3484	reviewed	Enzyme modulator
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10909	BXGT007630	Clusterin	1191	reviewed
P11217	BXGT007674	Glycogen phosphorylase, muscle form	5837	reviewed	Enzyme
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13612	BXGT007928	Integrin alpha-4	3676	reviewed
P13945	BXGT007972	Beta-3 adrenergic receptor	155	reviewed	G-protein coupled receptor
P14151	BXGT007990	L-selectin	6402	reviewed
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15090	BXGT008079	Fatty acid-binding protein, adipocyte	2167	reviewed
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15538	BXGT008137	Cytochrome P450 11B1, mitochondrial	1584	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16109	BXGT008194	P-selectin	6403	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P19099	BXGT008456	Cytochrome P450 11B2, mitochondrial	1585	reviewed
P19113	BXGT008458	Histidine decarboxylase	3067	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P20827	BXGT008606	Ephrin-A1	1942	reviewed	Kinase
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22413	BXGT008764	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	5167	reviewed	Enzyme
P22891	BXGT008813	Vitamin K-dependent protein Z	8858	reviewed	Enzyme
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P27037	BXGT009153	Activin receptor type-2A	92	reviewed	Kinase
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P29275	BXGT009328	Adenosine receptor A2b	136	reviewed	G-protein coupled receptor
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30411	BXGT009424	B2 bradykinin receptor	624	reviewed	G-protein coupled receptor
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35414	BXGT009829	Apelin receptor	187	reviewed	G-protein coupled receptor
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P38484	BXGT010042	Interferon gamma receptor 2	3460	reviewed	Receptor
P40189	BXGT010164	Interleukin-6 receptor subunit beta	3572	reviewed	Signaling
P40933	BXGT010209	Interleukin-15	3600	reviewed
P42330	BXGT010301	Aldo-keto reductase family 1 member C3	8644	reviewed	Enzyme
P42785	BXGT010338	Lysosomal Pro-X carboxypeptidase	5547	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P48775	BXGT010662	Tryptophan 2,3-dioxygenase	6999	reviewed	Enzyme
P49763	BXGT010737	Placenta growth factor	5228	reviewed	Signaling
P50052	BXGT010768	Type-2 angiotensin II receptor	186	reviewed	G-protein coupled receptor
P51589	BXGT010867	Cytochrome P450 2J2	1573	reviewed
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P78380	BXGT011841	Oxidized low-density lipoprotein receptor 1	4973	reviewed
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q07889	BXGT012946	Son of sevenless homolog 1	6654	reviewed	Enzyme modulator
Q13641	BXGT013390	Trophoblast glycoprotein	7162	reviewed	Receptor
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q15758	BXGT013594	Neutral amino acid transporter B(0)	6510	reviewed	Transporter
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q96IY4	BXGT019678	Carboxypeptidase B2	1361	reviewed	Enzyme
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9UHF0	BXGT021699	Tachykinin-3	6866	reviewed
Q9UHV8	BXGT021706	Galactoside-binding soluble lectin 13	29124	reviewed	Signaling
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
Q9Y5S8	BXGT022302	NADPH oxidase 1	27035	reviewed
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
Q96L73	BXGT024676	Histone-lysine N-methyltransferase, H3 lysine-36 specific	64324	reviewed	Epigenetic regulator
P49366	BXGT025175	Deoxyhypusine synthase	1725	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}