Showing entry for Factor V Leiden mutation


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD009579
Disease NameFactor V Leiden mutation
Disease CUI IdC0584960
MeSH Codes C16   C15  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00451 BXGT005545 Coagulation factor VIII 2157 reviewed Enzyme
P00488 BXGT005552 Coagulation factor XIII A chain 2162 reviewed Enzyme
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00740 BXGT005634 Coagulation factor IX 2158 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P01008 BXGT005713 Antithrombin-III 462 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02675 BXGT005916 Fibrinogen beta chain 2244 reviewed Signaling
P02749 BXGT005941 Beta-2-glycoprotein 1 350 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P04004 BXGT006125 Vitronectin 7448 reviewed
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P04070 BXGT006143 Vitamin K-dependent protein C 5624 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05546 BXGT006367 Heparin cofactor 2 3053 reviewed Enzyme modulator
P06744 BXGT006494 Glucose-6-phosphate isomerase 2821 reviewed Enzyme
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07359 BXGT006612 Platelet glycoprotein Ib alpha chain 2811 reviewed Receptor
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P08758 BXGT006821 Annexin A5 308 reviewed
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P11498 BXGT007714 Pyruvate carboxylase, mitochondrial 5091 reviewed Enzyme
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13497 BXGT007915 Bone morphogenetic protein 1 649 reviewed
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P16435 BXGT008226 NADPH--cytochrome P450 reductase 5447 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16581 BXGT008245 E-selectin 6401 reviewed
P17301 BXGT008299 Integrin alpha-2 3673 reviewed
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30536 BXGT009435 Translocator protein 706 reviewed
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42785 BXGT010338 Lysosomal Pro-X carboxypeptidase 5547 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
Q12882 BXGT013276 Dihydropyrimidine dehydrogenase [NADP(+)] 1806 reviewed Enzyme
Q14643 BXGT013493 Inositol 1,4,5-trisphosphate receptor type 1 3708 reviewed Ion channel
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q96IY4 BXGT019678 Carboxypeptidase B2 1361 reviewed Enzyme
Q9BQB6 BXGT020108 Vitamin K epoxide reductase complex subunit 1 79001 reviewed Enzyme
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
O75976 BXGT022954 Carboxypeptidase D 1362 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease