adisease

Showing entry for Drug usage

General Disease Information
BXGD Id	BXGD005173
Disease Name	Drug usage
Disease CUI Id	C0242510
MeSH Codes	C25 F03
Disease Class Name	Chemically-Induced Disorders; Mental Disorders
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O43293	BXGT004584	Death-associated protein kinase 3	1613	reviewed	Kinase
O43324	BXGT004588	Eukaryotic translation elongation factor 1 epsilon-1	9521	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
P00374	BXGT005520	Dihydrofolate reductase	1719	reviewed	Enzyme
P00480	BXGT005551	Ornithine carbamoyltransferase, mitochondrial	5009	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01275	BXGT005747	Glucagon	2641	reviewed
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02724	BXGT005934	Glycophorin-A	2993	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08236	BXGT006752	Beta-glucuronidase	2990	reviewed
P08913	BXGT006841	Alpha-2A adrenergic receptor	150	reviewed	G-protein coupled receptor
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P0DP23	BXGT007520	Calmodulin-1	808	reviewed
P0DP24	BXGT007521	Calmodulin-2	808	reviewed
P10276	BXGT007553	Retinoic acid receptor alpha	5914	reviewed	Nuclear receptor
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11509	BXGT007716	Cytochrome P450 2A6	1548	reviewed
P11712	BXGT007738	Cytochrome P450 2C9	1559	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13497	BXGT007915	Bone morphogenetic protein 1	649	reviewed
P13647	BXGT007937	Keratin, type II cytoskeletal 5	3852	reviewed
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14616	BXGT008026	Insulin receptor-related protein	3645	reviewed	Kinase
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15121	BXGT008083	Aldo-keto reductase family 1 member B1	231	reviewed	Enzyme
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P16581	BXGT008245	E-selectin	6401	reviewed
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P21917	BXGT008707	D(4) dopamine receptor	1815	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P23528	BXGT008879	Cofilin-1	1072	reviewed
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P25440	BXGT009044	Bromodomain-containing protein 2	6046	reviewed	Epigenetic regulator
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27338	BXGT009172	Amine oxidase [flavin-containing] B	4129	reviewed
P31639	BXGT009556	Sodium/glucose cotransporter 2	6524	reviewed	Transporter
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35462	BXGT009835	D(3) dopamine receptor	1814	reviewed	G-protein coupled receptor
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P41145	BXGT010225	Kappa-type opioid receptor	4986	reviewed	G-protein coupled receptor
P42785	BXGT010338	Lysosomal Pro-X carboxypeptidase	5547	reviewed	Enzyme
P43403	BXGT010385	Tyrosine-protein kinase ZAP-70	7535	reviewed	Kinase
P47869	BXGT010590	Gamma-aminobutyric acid receptor subunit alpha-2	2555	reviewed	Ion channel
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P55786	BXGT011125	Puromycin-sensitive aminopeptidase	9520	reviewed	Enzyme
P58004	BXGT011222	Sestrin-2	83667	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60981	BXGT011344	Destrin	11034	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P63146	BXGT011504	Ubiquitin-conjugating enzyme E2 B	7320	reviewed
P63279	BXGT011514	SUMO-conjugating enzyme UBC9	7329	reviewed
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q06520	BXGT012880	Bile salt sulfotransferase	6822	reviewed
Q07075	BXGT012917	Glutamyl aminopeptidase	2028	reviewed	Enzyme
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	775	reviewed	Ion channel
Q14416	BXGT013468	Metabotropic glutamate receptor 2	2912	reviewed	G-protein coupled receptor
Q14994	BXGT013519	Nuclear receptor subfamily 1 group I member 3	9970	reviewed	Nuclear receptor
Q16568	BXGT013640	Cocaine- and amphetamine-regulated transcript protein	9607	reviewed
Q9H2X3	BXGT020457	C-type lectin domain family 4 member M	10332	reviewed	Receptor
Q9UKU7	BXGT021749	Isobutyryl-CoA dehydrogenase, mitochondrial	27034	reviewed	Enzyme
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
P0DP25	BXGT024595	Calmodulin-3	808	reviewed
P38646	BXGT024954	Stress-70 protein, mitochondrial	3313	reviewed
P49366	BXGT025175	Deoxyhypusine synthase	1725	reviewed
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}