Showing entry for Aldehyde oxidase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012869
Protein NameAldehyde oxidase
Uniport IdQ06278
GeneAOX1
Gene Id316
DomainAld_Xan_dh_C; Ald_Xan_dh_C2; CO_deh_flav_C; FAD_binding_5; Fer2; Fer2_2
Pfam PF01315   PF02738   PF03450   PF00941   PF00111   PF01799  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00280 Valine, leucine and isoleucine degradation
1. Metabolism 1.5 Amino acid metabolism hsa00350 Tyrosine metabolism
1. Metabolism 1.5 Amino acid metabolism hsa00380 Tryptophan metabolism
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00750 Vitamin B6 metabolism
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00830 Retinol metabolism
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04630 Jak-STAT signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0017144 drug metabolic process
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0042816 vitamin B6 metabolic process
Biological Process GO:0009115 xanthine catabolic process
molecular function GO:0051537 2 iron, 2 sulfur cluster binding
molecular function GO:0004031 aldehyde oxidase activity
molecular function GO:0009055 electron transfer activity
molecular function GO:0071949 FAD binding
molecular function GO:0050660 flavin adenine dinucleotide binding
molecular function GO:0102797 geranial:oxygen oxidoreductase activity
molecular function GO:0102798 heptaldehyde:oxygen oxidoreductase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0005506 iron ion binding
molecular function GO:0043546 molybdopterin cofactor binding
molecular function GO:0051287 NAD binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0004854 xanthine dehydrogenase activity
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-964975 Vitamins B6 activation to pyridoxal phosphate
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004114 BXGD000255 Astrocytoma Neoplasms
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0025284 BXGD001849 Meningeal Neoplasms Neoplasms; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0268118 BXGD005820 Xanthinuria, Type I Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0268119 BXGD005821 Combined molybdoflavoprotein enzyme deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1707444 BXGD013586 Columnar Cell Change of the Breast
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0003707 Estrogen 268.36
BXGC0005624 Genistein 270.24
BXGC0014736 Isovanillin 152.05
BXGC0019164 Raloxifene 473.17
BXGC0025848 XK-469 free acid, (R)- 344.06
BXGC0026391 Naloxone 327.15
BXGC0042222 Propranolol 259.16
BXGC0044200 Menadione 172.05
BXGC0047242 Pyridoxal 167.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein