Showing entry for Transforming growth factor beta activator LRRC32


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013465
Protein NameTransforming growth factor beta activator LRRC32
Uniport IdQ14392
GeneLRRC32
Gene Id2615
DomainLRRNT; LRR_8
Pfam PF13855   PF01462  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046007 negative regulation of activated T cell proliferation
Biological Process GO:0050710 negative regulation of cytokine secretion
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:1901398 regulation of transforming growth factor beta3 activation
Biological Process GO:1901388 regulation of transforming growth factor beta activation
Biological Process GO:0062009 secondary palate development
Biological Process GO:0007179 transforming growth factor beta receptor signaling pathway
molecular function GO:0050431 transforming growth factor beta binding
cellular component GO:0009986 cell surface
cellular component GO:0031012 extracellular matrix
cellular component GO:0005615 extracellular space
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0008312 BXGD000527 Primary biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014335 BXGD000908 Enteritis Digestive System Diseases
C0018621 BXGD001210 Hay fever Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C0019360 BXGD001327 Herpes zoster disease Infections
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0040128 BXGD002844 Thyroid Diseases Endocrine System Diseases
C0079680 BXGD003085 Lentivirus Infections Infections
C0205822 BXGD004126 Hibernoma Neoplasms
C0238124 BXGD004883 Necrotizing fasciitis Musculoskeletal Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0264408 BXGD005387 Childhood asthma Respiratory Tract Diseases; Immune System Diseases
C0339467 BXGD007248 Proliferative retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0341106 BXGD007389 Eosinophilic esophagitis Digestive System Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0343532 BXGD007633 Streptococcal toxic shock syndrome Pathological Conditions, Signs and Symptoms; Infections
C0344290 BXGD007662 Vitreoretinal degeneration
C0409952 BXGD008399 Idiopathic osteoarthritis Musculoskeletal Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0477474 BXGD009003 Dermatitis and eczema Skin and Connective Tissue Diseases
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0557874 BXGD009444 Global developmental delay
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0751967 BXGD010657 Multiple Sclerosis, Relapsing-Remitting Immune System Diseases; Nervous System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1274233 BXGD012028 T-lymphocyte immunodeficiency Immune System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1384584 BXGD012943 Generalized osteoarthritis Musculoskeletal Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1527304 BXGD013266 Allergic Reaction Immune System Diseases
C1611743 BXGD013456 Familial (FPAH)
C1832097 BXGD013797 EPIDERMAL DIFFERENTIATION COMPLEX
C1837218 BXGD014207 Cleft palate, isolated Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C1848638 BXGD014952 USHER SYNDROME, TYPE IB (disorder) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C2981150 BXGD018211 Uranostaphyloschisis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4048329 BXGD021904 Immunosuppression
C4554344 BXGD023564 IgE-mediated food allergy Immune System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018397 beta-1,4-mannan 180.06
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein