Showing entry for Misshapen-like kinase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018510
Protein NameMisshapen-like kinase 1
Uniport IdQ8N4C8
GeneMINK1
Gene Id50488
DomainCNH; Pkinase
Pfam PF00780   PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031532 actin cytoskeleton reorganization
Biological Process GO:0032147 activation of protein kinase activity
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0048813 dendrite morphogenesis
Biological Process GO:0007254 JNK cascade
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0048812 neuron projection morphogenesis
Biological Process GO:0046330 positive regulation of JNK cascade
Biological Process GO:1900745 positive regulation of p38MAPK cascade
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:2000311 regulation of AMPA receptor activity
Biological Process GO:0022407 regulation of cell-cell adhesion
Biological Process GO:0001952 regulation of cell-matrix adhesion
Biological Process GO:0030334 regulation of cell migration
Biological Process GO:0023014 signal transduction by protein phosphorylation
Biological Process GO:0031098 stress-activated protein kinase signaling cascade
molecular function GO:0005524 ATP binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0030424 axon
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0070062 extracellular exosome
cellular component GO:0005794 Golgi apparatus
cellular component GO:0014069 postsynaptic density
Reactome
Pathway Id Pathway Name
R-HSA-2262752 Cellular responses to stress
R-HSA-2559580 Oxidative Stress Induced Senescence
R-HSA-2559583 Cellular Senescence
R-HSA-8953897 Cellular responses to external stimuli
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007766 BXGD000478 Intracranial Aneurysm Nervous System Diseases; Cardiovascular Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0015302 BXGD000974 External exotoses Musculoskeletal Diseases
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0023976 BXGD001724 Long QT Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0200635 BXGD004041 Lymphocyte Count measurement
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0340489 BXGD007336 Lone atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0523744 BXGD009217 Lipids measurement
C1269955 BXGD012005 Tumor Cell Invasion
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1956089 BXGD016615 Osteophyte Musculoskeletal Diseases
C2363741 BXGD017100 HIV-1 infection
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012352 Chelerythrine 348.12
BXGC0024554 D-luciferin 280
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein