Showing entry for Glutamate receptor ionotropic, NMDA 3A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018802
Protein NameGlutamate receptor ionotropic, NMDA 3A
Uniport IdQ8TCU5
GeneGRIN3A
Gene Id116443
DomainLig_chan; Lig_chan-Glu_bd
Pfam PF00060   PF10613  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
5. Organismal Systems 5.6 Nervous system hsa04724 Glutamatergic synapse
6. Human Diseases 6.5 Substance dependence hsa05030 Cocaine addiction
6. Human Diseases 6.5 Substance dependence hsa05031 Amphetamine addiction
6. Human Diseases 6.5 Substance dependence hsa05033 Nicotine addiction
6. Human Diseases 6.5 Substance dependence hsa05034 Alcoholism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0016358 dendrite development
Biological Process GO:0035235 ionotropic glutamate receptor signaling pathway
Biological Process GO:0060134 prepulse inhibition
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0045471 response to ethanol
molecular function GO:0005262 calcium channel activity
molecular function GO:0016594 glycine binding
molecular function GO:0042802 identical protein binding
molecular function GO:0015276 ligand-gated ion channel activity
molecular function GO:0004972 NMDA glutamate receptor activity
molecular function GO:0051721 protein phosphatase 2A binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0017146 NMDA selective glutamate receptor complex
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-112316 Neuronal System
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors
R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0007789 BXGD000488 Cerebral Palsy Nervous System Diseases
C0010051 BXGD000646 Coronary Aneurysm Cardiovascular Diseases
C0011206 BXGD000703 Delirium Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0019337 BXGD001319 Heroin Dependence Chemically-Induced Disorders; Mental Disorders
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0026691 BXGD001917 Mucocutaneous Lymph Node Syndrome Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0028043 BXGD002066 Nicotine Dependence Chemically-Induced Disorders; Mental Disorders
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0085281 BXGD003152 Addictive Behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0242350 BXGD005154 Erectile dysfunction Male Urogenital Diseases; Mental Disorders
C0265552 BXGD005546 Congenital macrodactylia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0282577 BXGD006816 Congenital Disorders of Glycosylation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0347197 BXGD007851 Benign neoplasm of oral cavity Digestive System Diseases; Neoplasms; Stomatognathic Diseases
C0596887 BXGD009648 mathematical ability
C1305855 BXGD012348 Body mass index
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C1842937 BXGD014546 AURAL ATRESIA, CONGENITAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C4721772 BXGD023767 Postoperative delirium Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000434 Ethanol 46.07
BXGC0003196 Aripiprazole 448.39
BXGC0006162 L-Glutamic acid 147.13
BXGC0025485 Transtorine 189.04
BXGC0028885 Secobarbital 238.13
BXGC0033112 Acetylcysteine 163.03
BXGC0043578 5-Hydroxy-2-(2-Phenylethyl)Chromen-4-One 266.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein