Showing entry for Isovitexin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0000324
Compound NameIsovitexin
Structure
FormulaC21H20O10
InchiKeyMYXNWGACZJSMBT-UHFFFAOYSA-N
SMILESOCC1OC(C(O)C(O)C1O)C1=C(O)C2=C(OC(=CC2=O)C2=CC=C(O)C=C2)C=C1O
InchiInChI=1S/C21H20O10/c22-7-14-17(26)19(28)20(29)21(31-14)16-11(25)6-13-15(18(16)27)10(24)5-12(30-13)8-1-3-9(23)4-2-8/h1-6,14,17,19-23,25-29H,7H2
IUPAC5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-4H-chromen-4-one
Molecular Weight432.38
Pubchem Id4475102
Chembl IdCHEMBL1601394
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 60722
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT009492 Neurotensin receptor type 1 reviewed G-protein coupled receptor NTSR1 - - - 2710
reviewed BXGT005956 Serum albumin reviewed ALB - >94115 - -
reviewed BXGT005130 PC4 and SFRS1-interacting protein reviewed Signaling PSIP1 - 2619 - -
reviewed BXGT005130 PC4 and SFRS1-interacting protein reviewed Signaling PSIP1 - 5957 - -
CHEMBL CHEMBL1601394
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P30989 BXGT009492 Neurotensin receptor type 1 reviewed G-protein coupled receptor NTSR1 EC50 '=' 2710 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 35481 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 35481 nM
O75164 BXGT005104 Lysine-specific demethylase 4A reviewed - KDM4A Potency - 79432 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency '=' 35481 nM
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase reviewed Enzyme WRN Potency - 50118 nM
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial reviewed Enzyme GLS Potency - 12589 nM
P03070 BXGT006016 Large T antigen reviewed - IC50 - 21430 nM
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 112201 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 112201 nM
P06746 BXGT006496 DNA polymerase beta reviewed Enzyme POLB Potency '=' 8912 nM
P07378 BXGT006616 Phosphoglycerate kinase, glycosomal reviewed - Potency - 19952 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency '=' 12589 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 39810 nM
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 reviewed - PIN1 Potency - 63095 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency - 50118 nM
Q962Y6 BXGT019597 Thioredoxin glutathione reductase unreviewed - TGR Potency '=' 70794 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 28183 nM
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 19952 nM
P02769 BXGT005956 Serum albumin reviewed - ALB IC50 '>' 94115 nM
P39748 BXGT010134 Flap endonuclease 1 reviewed Enzyme FEN1 Potency - 50118 nM
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 89125 nM
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 22387 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 22387 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 35481 nM
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 23934 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 18348 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 23099 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 28183 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 33587 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 29092 nM
Q8WZA2 BXGT019025 Rap guanine nucleotide exchange factor 4 reviewed Enzyme modulator RAPGEF4 Potency - 79432 nM
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA Potency '=' 35481 nM
P17405 BXGT008304 Sphingomyelin phosphodiesterase reviewed Enzyme SMPD1 Potency - 25118 nM
Q9Y468 BXGT022270 Lethal(3)malignant brain tumor-like protein 1 reviewed Epigenetic regulator L3MBTL1 Potency '=' 15848 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 7079 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 100000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 23109 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00019 Tarragon Artemisia dracunculus Herbs and Spices
BXGF00022 Oat Avena sativa Cereals and cereal products
BXGF00038 Tea Camellia sinensis Teas
BXGF00054 Lemon Citrus limon Fruits
BXGF00064 Muskmelon Cucumis melo Gourds
BXGF00065 Cucumber Cucumis sativus Gourds
BXGF00079 Common buckwheat Fagopyrum esculentum Cereals and cereal products
BXGF00088 Barley Hordeum vulgare Cereals and cereal products
BXGF00101 Flaxseed Linum usitatissimum Herbs and Spices
BXGF00124 Common oregano Origanum vulgare Herbs and Spices
BXGF00137 Anise Pimpinella anisum Herbs and Spices
BXGF00141 Common pea Pisum sativum Pulses
BXGF00180 Tamarind Tamarindus indica Fruits
BXGF00182 Cocoa bean Theobroma cacao Cocoa and cocoa products
BXGF00186 Fenugreek Trigonella foenum-graecum Herbs and Spices
BXGF00199 Gram bean Vigna mungo Pulses
BXGF00200 Mung bean Vigna radiata Pulses
BXGF00403 Prairie turnip Pediomelum esculentum Vegetables
BXGF00420 Common salsify Tragopogon porrifolius Vegetables
BXGF00466 Winged bean Psophocarpus tetragonolobus Pulses
BXGF00823 Fruits Fruits
BXGF05571 Ziziphus jujuba Ziziphus jujuba Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease