Showing entry for Angiopoietin-1 receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012667
Protein NameAngiopoietin-1 receptor
Uniport IdQ02763
GeneTEK
Gene Id7010
Domainfn3; Ig_Tie2_1; Pkinase_Tyr
Pfam PF00041   PF10430   PF07714  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04014 Ras signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04015 Rap1 signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04066 HIF-1 signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04151 PI3K-Akt signaling pathway
6. Human Diseases 6.3 Immune diseases hsa05323 Rheumatoid arthritis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001525 angiogenesis
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0060216 definitive hemopoiesis
Biological Process GO:0001958 endochondral ossification
Biological Process GO:0001935 endothelial cell proliferation
Biological Process GO:0072012 glomerulus vasculature development
Biological Process GO:0007507 heart development
Biological Process GO:0060347 heart trabecula formation
Biological Process GO:0050900 leukocyte migration
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0016525 negative regulation of angiogenesis
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:2000352 negative regulation of endothelial cell apoptotic process
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:2000251 positive regulation of actin cytoskeleton reorganization
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0010595 positive regulation of endothelial cell migration
Biological Process GO:0001938 positive regulation of endothelial cell proliferation
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0051894 positive regulation of focal adhesion assembly
Biological Process GO:1902533 positive regulation of intracellular signal transduction
Biological Process GO:0033674 positive regulation of kinase activity
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
Biological Process GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
Biological Process GO:0051897 positive regulation of protein kinase B signaling
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:2000351 regulation of endothelial cell apoptotic process
Biological Process GO:0032878 regulation of establishment or maintenance of cell polarity
Biological Process GO:0043114 regulation of vascular permeability
Biological Process GO:0051591 response to cAMP
Biological Process GO:0043627 response to estrogen
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0043434 response to peptide hormone
Biological Process GO:0007165 signal transduction
Biological Process GO:0002040 sprouting angiogenesis
Biological Process GO:0034446 substrate adhesion-dependent cell spreading
Biological Process GO:0048014 Tie signaling pathway
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0019838 growth factor binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0038023 signaling receptor activity
molecular function GO:0004714 transmembrane receptor protein tyrosine kinase activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0009925 basal plasma membrane
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005911 cell-cell junction
cellular component GO:0009986 cell surface
cellular component GO:0034451 centriolar satellite
cellular component GO:0005737 cytoplasm
cellular component GO:0005576 extracellular region
cellular component GO:0005925 focal adhesion
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005902 microvillus
cellular component GO:0005886 plasma membrane
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-109582 Hemostasis
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-168256 Immune System
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-210993 Tie2 Signaling
R-HSA-210993 Tie2 Signaling
R-HSA-5673001 RAF/MAP kinase cascade
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5684996 MAPK1/MAPK3 signaling
R-HSA-9607240 FLT3 Signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000744 BXGD000006 Abetalipoproteinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002312 BXGD000107 alpha-Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002631 BXGD000123 Infection of amniotic cavity Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003857 BXGD000228 Congenital arteriovenous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003872 BXGD000235 Arthritis, Psoriatic Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004610 BXGD000281 Bacteremia Pathological Conditions, Signs and Symptoms; Infections
C0005411 BXGD000313 Biliary Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0008372 BXGD000535 Intrahepatic Cholestasis Digestive System Diseases
C0008495 BXGD000548 Chorioamnionitis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009763 BXGD000628 Conjunctivitis Eye Diseases
C0009766 BXGD000629 Allergic Conjunctivitis Eye Diseases; Immune System Diseases
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0012546 BXGD000776 Diphtheria Infections
C0012739 BXGD000786 Disseminated Intravascular Coagulation Hemic and Lymphatic Diseases
C0013604 BXGD000859 Edema Pathological Conditions, Signs and Symptoms
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0014558 BXGD000933 Uncinate Epilepsy Nervous System Diseases
C0015230 BXGD000969 Exanthema Skin and Connective Tissue Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018021 BXGD001162 Goiter Endocrine System Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018798 BXGD001223 Congenital Heart Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0018916 BXGD001245 Hemangioma Neoplasms
C0018920 BXGD001246 Hemangioma, Cavernous Neoplasms; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0018923 BXGD001248 Hemangiosarcoma Neoplasms
C0018939 BXGD001253 Hematological Disease Hemic and Lymphatic Diseases
C0019207 BXGD001303 Hepatoma, Morris Digestive System Diseases; Neoplasms
C0019208 BXGD001304 Hepatoma, Novikoff Digestive System Diseases; Neoplasms
C0020302 BXGD001373 Hydrophthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0020452 BXGD001389 Hyperemia Cardiovascular Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020981 BXGD001474 Angioimmunoblastic Lymphadenopathy Immune System Diseases; Hemic and Lymphatic Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022672 BXGD001574 Acute Kidney Tubular Necrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0023418 BXGD001642 leukemia Neoplasms
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023462 BXGD001654 Acute Megakaryocytic Leukemias Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023470 BXGD001659 Myeloid Leukemia Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0023904 BXGD001721 Liver Neoplasms, Experimental Digestive System Diseases; Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024221 BXGD001747 Lymphangioma Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025500 BXGD001874 Mesothelioma Neoplasms
C0026633 BXGD001910 Mouth Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0027022 BXGD001962 Myeloproliferative disease Hemic and Lymphatic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027055 BXGD001964 Myocardial Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027668 BXGD002019 Neoplasms, Vascular Tissue Neoplasms
C0027686 BXGD002021 Pathologic Neovascularization Pathological Conditions, Signs and Symptoms
C0027809 BXGD002040 Neurilemmoma Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027873 BXGD002054 Neuromyelitis Optica Eye Diseases; Immune System Diseases; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028840 BXGD002089 Ocular Hypertension Eye Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0032044 BXGD002324 Placenta Accreta Female Urogenital Diseases and Pregnancy Complications
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032914 BXGD002379 Pre-Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0035305 BXGD002529 Retinal Detachment Eye Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035344 BXGD002541 Retinopathy of Prematurity Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037116 BXGD002666 Silicosis Respiratory Tract Diseases; Occupational Diseases
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0038358 BXGD002748 Gastric ulcer Digestive System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038505 BXGD002765 Sturge-Weber Syndrome Neoplasms; Nervous System Diseases; Cardiovascular Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041316 BXGD002908 Lymph Node Tuberculosis Infections
C0041327 BXGD002916 Tuberculosis, Pulmonary Infections; Respiratory Tract Diseases
C0041948 BXGD002939 Uremia Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0041974 BXGD002945 Urethral Stenosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042961 BXGD003017 Intestinal Volvulus Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0043037 BXGD003023 Common wart Neoplasms; Infections; Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079774 BXGD003101 Peripheral T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085109 BXGD003125 Corneal Neovascularization Pathological Conditions, Signs and Symptoms; Eye Diseases
C0085110 BXGD003126 Severe Combined Immunodeficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0085411 BXGD003169 Angiodysplasia Cardiovascular Diseases
C0085576 BXGD003188 Iron-Refractory Iron Deficiency Anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0085702 BXGD003247 Monocytosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0086404 BXGD003278 Experimental Hepatoma Digestive System Diseases; Neoplasms
C0149871 BXGD003375 Deep Vein Thrombosis Cardiovascular Diseases
C0151529 BXGD003433 Prolonged bleeding time
C0151811 BXGD003478 Subcutaneous nodule Neoplasms; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0151825 BXGD003481 Bone pain Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0153467 BXGD003653 Malignant tumor of peritoneum Digestive System Diseases; Neoplasms; Skin and Connective Tissue Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0155765 BXGD003819 Disease of capillaries Cardiovascular Diseases
C0158570 BXGD003892 Vascular anomaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0162770 BXGD003980 Right Ventricular Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205789 BXGD004123 Hemangioma, Intramuscular Neoplasms
C0206061 BXGD004147 Pneumonia, Interstitial Respiratory Tract Diseases
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0206734 BXGD004279 Hemangioblastoma Neoplasms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220656 BXGD004312 Malignant ascites Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0235752 BXGD004766 Port-Wine Stain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0235833 BXGD004775 Congenital diaphragmatic hernia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242994 BXGD005205 Hantavirus Infections Infections
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0265950 BXGD005588 Venous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0267370 BXGD005739 Angiodysplasia of colon Digestive System Diseases; Cardiovascular Diseases
C0267373 BXGD005741 Intestinal hemorrhage NOS Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0269062 BXGD006051 Chronic cervicitis Female Urogenital Diseases and Pregnancy Complications; Infections
C0271084 BXGD006159 Exudative age-related macular degeneration Eye Diseases
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0278619 BXGD006550 Extramedullary Plasmacytoma Neoplasms; Immune System Diseases
C0278689 BXGD006563 Recurrent ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0302142 BXGD006831 Deformity Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0334533 BXGD007105 Arteriovenous hemangioma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Cardiovascular Diseases
C0339573 BXGD007271 Glaucoma, Primary Open Angle Eye Diseases
C0340803 BXGD007366 Capillary malformation (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0344530 BXGD007688 Congenital keratoglobus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346072 BXGD007775 Blue rubber bleb nevus syndrome Digestive System Diseases; Neoplasms; Skin and Connective Tissue Diseases
C0346153 BXGD007781 Breast Cancer, Familial Neoplasms; Skin and Connective Tissue Diseases
C0346957 BXGD007836 Disseminated Malignant Neoplasm Neoplasms
C0349639 BXGD007943 Juvenile Myelomonocytic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0349782 BXGD007954 Ischemic cardiomyopathy Cardiovascular Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0393672 BXGD008115 Epilepsy, Benign Psychomotor, Childhood Nervous System Diseases
C0393682 BXGD008117 Epilepsy, Lateral Temporal Nervous System Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0406500 BXGD008347 Lipodermatosclerosis Skin and Connective Tissue Diseases
C0432283 BXGD008764 Osteoglophonic dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0521158 BXGD009130 Recurrent tumor
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0596298 BXGD009641 Cerebrovascular Occlusion Nervous System Diseases; Cardiovascular Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0600452 BXGD009708 Hepatopulmonary Syndrome Digestive System Diseases; Respiratory Tract Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0684256 BXGD009791 Bacterial sepsis Pathological Conditions, Signs and Symptoms; Infections
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0700636 BXGD009898 Focal nodular hyperplasia of liver Digestive System Diseases
C0730285 BXGD009943 Diabetic macular edema Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0740447 BXGD009998 Diabetic peripheral neuropathy Nervous System Diseases; Endocrine System Diseases
C0741916 BXGD010044 Cardiac defects
C0749557 BXGD010221 toe necrosis
C0752304 BXGD010711 Hypoxic-Ischemic Encephalopathy Nervous System Diseases; Cardiovascular Diseases
C0851887 BXGD010930 Adenoviral infections
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C0878773 BXGD011391 Overactive Bladder Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1335177 BXGD012771 Ovarian Serous Adenocarcinoma Neoplasms
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1384590 BXGD012944 Hemangiomatosis Neoplasms; Cardiovascular Diseases
C1402315 BXGD013017 Vascular lesions
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1456868 BXGD013128 Diabetic foot ulcer Skin and Connective Tissue Diseases; Endocrine System Diseases; Cardiovascular Diseases
C1456873 BXGD013129 alpha^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1511566 BXGD013182 cutaneous B-cell non-Hodgkin lymphoma
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1533041 BXGD013307 Primary congenital glaucoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1658953 BXGD013486 tumor vasculature
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1832977 BXGD013891 GLAUCOMA 3, PRIMARY INFANTILE, B Eye Diseases
C1838437 BXGD014314 VENOUS MALFORMATIONS, MULTIPLE CUTANEOUS AND MUCOSAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1841984 BXGD014487 GLOMUVENOUS MALFORMATIONS Neoplasms
C1846821 BXGD014841 Abnormality of coagulation
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1961121 BXGD016675 Congenital vascular anomaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1963077 BXGD016680 Bone Pain, CTCAE 3.0
C1969372 BXGD016775 Tubulointerstitial fibrosis
C2215101 BXGD016944 Acute cerebral ischemia Nervous System Diseases; Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2676033 BXGD017322 Hepatoblastoma Caused By Somatic Mutation Digestive System Diseases; Neoplasms
C2919945 BXGD017882 Cavernous Hemangioma of Brain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C2930967 BXGD017920 Gastro-enteropancreatic neuroendocrine tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C2931852 BXGD018079 Clear-cell metastatic renal cell carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2937220 BXGD018154 Congenital abnormality of vein Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2945695 BXGD018187 Limb ischemia
C2985280 BXGD018223 Blood Protein Measurement
C3152231 BXGD018463 Gastrointestinal infarctions
C3160844 BXGD018482 PAI-1 polymorphism
C3178801 BXGD018538 Stroke, Lacunar Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3539781 BXGD019086 Progressive cGVHD
C3665346 BXGD019278 Unspecified visual loss Pathological Conditions, Signs and Symptoms; Eye Diseases
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3665386 BXGD019284 Abnormal vision Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3665444 BXGD019288 Neutrophilia (disorder) Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C4021977 BXGD020853 Visceral angiomatosis
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4310639 BXGD022610 GLAUCOMA 3, PRIMARY CONGENITAL, E
C4520983 BXGD023052 Congenital atresia of extrahepatic bile duct Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4551691 BXGD023394 Urethral stricture Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4554063 BXGD023559 Bone Pain, CTCAE 5.0
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002063 Alternariol 258.23
BXGC0004714 2-Methoxy-1,4-benzoquinone 138.12
BXGC0006193 Ellagic acid 302.19
BXGC0012352 Chelerythrine 348.12
BXGC0017701 Altenusin 290.08
BXGC0017933 Sulfuretin 270.05
BXGC0018397 beta-1,4-mannan 180.06
BXGC0035685 alternariol monomethyl ether 272.07
BXGC0038991 Selenomethionine 197
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050194 alpha-D-Mannose 180.06
BXGC0051819 Altertoxin I 352.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein