adisease

Showing entry for Bronchiectasis

General Disease Information
BXGD Id	BXGD000383
Disease Name	Bronchiectasis
Disease CUI Id	C0006267
MeSH Codes	C08
Disease Class Name	Respiratory Tract Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0002086
Human Phenotype Ontology Term	Abnormality of the respiratory system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00182	BXGT003889	Galectin-9	3965	reviewed	Signaling
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75369	BXGT005119	Filamin-B	2317	reviewed
O76054	BXGT005172	SEC14-like protein 2	23541	reviewed
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01732	BXGT005782	T-cell surface glycoprotein CD8 alpha chain	925	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P05156	BXGT006329	Complement factor I	3426	reviewed
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11912	BXGT007758	B-cell antigen receptor complex-associated protein alpha chain	973	reviewed	Receptor
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15814	BXGT008159	Immunoglobulin lambda-like polypeptide 1	3543	reviewed
P15924	BXGT008171	Desmoplakin	1832	reviewed	Cellular structure
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20936	BXGT008619	Ras GTPase-activating protein 1	5921	reviewed	Enzyme modulator
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P31025	BXGT009500	Lipocalin-1	3933	reviewed	Enzyme
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35247	BXGT009804	Pulmonary surfactant-associated protein D	6441	reviewed	Surfactant
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48147	BXGT010620	Prolyl endopeptidase	5550	reviewed	Enzyme
P49913	BXGT010761	Cathelicidin antimicrobial peptide	820	reviewed
P51168	BXGT010842	Amiloride-sensitive sodium channel subunit beta	6338	reviewed	Ion channel
P51170	BXGT010843	Amiloride-sensitive sodium channel subunit gamma	6340	reviewed	Ion channel
P54132	BXGT011032	Bloom syndrome protein	641	reviewed
P55899	BXGT011131	IgG receptor FcRn large subunit p51	2217	reviewed
P60033	BXGT011286	CD81 antigen	975	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P78556	BXGT011849	C-C motif chemokine 20	6364	reviewed	Signaling
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13546	BXGT013372	Receptor-interacting serine/threonine-protein kinase 1	8737	reviewed	Kinase
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15485	BXGT013574	Ficolin-2	2220	reviewed	Signaling
Q6NYC1	BXGT016436	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	23210	reviewed	Receptor
Q92834	BXGT019381	X-linked retinitis pigmentosa GTPase regulator	6103	reviewed
Q96RJ3	BXGT019729	Tumor necrosis factor receptor superfamily member 13C	115650	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9HBE5	BXGT020518	Interleukin-21 receptor	50615	reviewed	Receptor
Q9NPH2	BXGT021158	Inositol-3-phosphate synthase 1	51477	reviewed
Q9NRP7	BXGT021192	Serine/threonine-protein kinase 36	27148	reviewed	Kinase
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
P51784	BXGT023311	Ubiquitin carboxyl-terminal hydrolase 11	8237	reviewed	Enzyme
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
P19474	BXGT025520	E3 ubiquitin-protein ligase TRIM21	6737	reviewed
Q9P121	BXGT025711	Neurotrimin	50863	reviewed
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
Q7LBE3	BXGT026071	Solute carrier family 26 member 9	115019	reviewed	Transporter
Q92888	BXGT026130	Rho guanine nucleotide exchange factor 1	9138	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}