Showing entry for Tumor necrosis factor receptor superfamily member 13C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019729
Protein NameTumor necrosis factor receptor superfamily member 13C
Uniport IdQ96RJ3
GeneTNFRSF13C
Gene Id115650
DomainBaffR-Tall_bind
Pfam PF09256  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction
3. Environmental Information Processing 3.2 Signal transduction hsa04064 NF-kappa B signaling pathway
5. Organismal Systems 5.1 Immune system hsa04672 Intestinal immune network for IgA production
6. Human Diseases 6.9 Infectious diseases: Viral hsa05166 Human T-cell leukemia virus 1 infection
6. Human Diseases 6.3 Immune diseases hsa05340 Primary immunodeficiency
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0031296 B cell costimulation
Biological Process GO:0001782 B cell homeostasis
Biological Process GO:0030890 positive regulation of B cell proliferation
Biological Process GO:0002636 positive regulation of germinal center formation
Biological Process GO:0032729 positive regulation of interferon-gamma production
Biological Process GO:0042102 positive regulation of T cell proliferation
Biological Process GO:0031295 T cell costimulation
Biological Process GO:0033209 tumor necrosis factor-mediated signaling pathway
molecular function GO:0038023 signaling receptor activity
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-168256 Immune System
R-HSA-5668541 TNFR2 non-canonical NF-kB pathway
R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0003466 BXGD000193 Anus, Imperforate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003862 BXGD000230 Arthralgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004368 BXGD000271 Autoimmune state
C0004943 BXGD000297 Behcet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006267 BXGD000383 Bronchiectasis Respiratory Tract Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0009447 BXGD000613 Common Variable Immunodeficiency Immune System Diseases
C0009763 BXGD000628 Conjunctivitis Eye Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013990 BXGD000874 Pathological accumulation of air in tissues Pathological Conditions, Signs and Symptoms
C0014060 BXGD000882 Encephalitis, St. Louis Infections; Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0018203 BXGD001184 Chronic granulomatous disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020445 BXGD001386 Hypercholesterolemia, Familial Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023443 BXGD001648 Hairy Cell Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023896 BXGD001718 Alcoholic Liver Diseases Digestive System Diseases; Chemically-Induced Disorders
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024312 BXGD001766 Lymphopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0024314 BXGD001767 Lymphoproliferative Disorders Immune System Diseases; Hemic and Lymphatic Diseases
C0024408 BXGD001768 Machado-Joseph Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0024419 BXGD001769 Waldenstrom Macroglobulinemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0025289 BXGD001851 Meningitis Nervous System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026896 BXGD001946 Myasthenia Gravis Neoplasms; Immune System Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032302 BXGD002347 Mycoplasma pneumonia Infections; Respiratory Tract Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034150 BXGD002466 Purpura Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0034155 BXGD002468 Purpura, Thrombotic Thrombocytopenic Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0042384 BXGD002979 Vasculitis Cardiovascular Diseases
C0043124 BXGD003031 West Nile Fever Infections; Nervous System Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079772 BXGD003099 T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0151449 BXGD003419 Primary Sjögren's syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0220605 BXGD004294 Adult Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0220612 BXGD004296 Childhood Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0221026 BXGD004371 X-linked agammaglobulinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C0221356 BXGD004448 Brachycephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0242647 BXGD005184 Mucosa-Associated Lymphoid Tissue Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0271441 BXGD006203 Chronic otitis media Otorhinolaryngologic Diseases
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0278764 BXGD006581 Adult Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278879 BXGD006610 Childhood Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279584 BXGD006641 Childhood B Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0279593 BXGD006644 Adult B Acute Lymphoblastic Leukemia
C0280483 BXGD006750 Adult Anaplastic Astrocytoma Neoplasms
C0334579 BXGD007120 Anaplastic astrocytoma Neoplasms
C0349636 BXGD007941 Pre B-cell acute lymphoblastic leukemia
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0398650 BXGD008212 Immune thrombocytopenic purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
C0497156 BXGD009053 Lymphadenopathy Hemic and Lymphatic Diseases
C0581354 BXGD009561 Recurrent sinusitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0694550 BXGD009852 Recurrent pneumonia Infections; Respiratory Tract Diseases
C0741796 BXGD010041 Recurrent bronchitis Infections; Respiratory Tract Diseases
C0747085 BXGD010158 Recurrent otitis media Otorhinolaryngologic Diseases
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0858762 BXGD011190 Neuro-Behcet disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0919715 BXGD011436 Lupus-like syndrome Skin and Connective Tissue Diseases
C0947912 BXGD011497 Myasthenias Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1096184 BXGD011607 West Nile viral infection Infections; Nervous System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1328840 BXGD012474 Autoimmune Lymphoproliferative Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1535939 BXGD013323 Pneumocystis jiroveci pneumonia Infections; Respiratory Tract Diseases
C1844383 BXGD014628 Recurrent bacterial infection Infections
C1848389 BXGD014920 Posterior pharyngeal cleft
C1848701 BXGD014967 Elevated hepatic transaminase
C1850900 BXGD015186 Familial primary gastric lymphoma Digestive System Diseases; Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1860127 BXGD015956 Impaired T cell function
C1867873 BXGD016473 Failure to thrive in infancy
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2936664 BXGD018125 Acquired Hypogammaglobulinemia Immune System Diseases
C2936665 BXGD018126 Immunoglobulin Deficiency, Late-Onset Immune System Diseases
C3150739 BXGD018329 IMMUNODEFICIENCY, COMMON VARIABLE, 4
C3277226 BXGD018711 Restrictive ventilatory defect
C4014733 BXGD020162 Follicular hyperplasia Hemic and Lymphatic Diseases
C4048270 BXGD021897 Decreased antibody level in blood
C4551548 BXGD023342 Grade III Childhood Astrocytoma Neoplasms
C4721532 BXGD023752 Lymphoma, Non-Hodgkin, Familial Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004275 Acetaldehyde 44.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein