adisease

Showing entry for Cystic kidney

General Disease Information
BXGD Id	BXGD001575
Disease Name	Cystic kidney
Disease CUI Id	C0022679
MeSH Codes	C13 C12
Disease Class Name	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000119
Human Phenotype Ontology Term	Abnormality of the genitourinary system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00444	BXGT003921	Serine/threonine-protein kinase PLK4	10733	reviewed	Kinase
O15230	BXGT004138	Laminin subunit alpha-5	3911	reviewed	Enzyme modulator
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O94813	BXGT005337	Slit homolog 2 protein	9353	reviewed
O94925	BXGT005342	Glutaminase kidney isoform, mitochondrial	2744	reviewed	Enzyme
P00751	BXGT005643	Complement factor B	629	reviewed
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P05231	BXGT006345	Interleukin-6	3569	reviewed
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P18085	BXGT008377	ADP-ribosylation factor 4	378	reviewed
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P27815	BXGT009208	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	5141	reviewed
P30518	BXGT009428	Vasopressin V2 receptor	554	reviewed	G-protein coupled receptor
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P54750	BXGT011072	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	5136	reviewed
P54760	BXGT011075	Ephrin type-B receptor 4	2050	reviewed	Kinase
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q13418	BXGT013351	Integrin-linked protein kinase	3611	reviewed	Kinase
Q13563	BXGT013377	Polycystin-2	5311	reviewed	Ion channel
Q15139	BXGT013546	Serine/threonine-protein kinase D1	5587	reviewed	Kinase
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q68DC2	BXGT016189	Ankyrin repeat and SAM domain-containing protein 6	203286	reviewed
Q7Z494	BXGT017254	Nephrocystin-3	27031	reviewed
Q9NQH7	BXGT021164	Xaa-Pro aminopeptidase 3	63929	reviewed	Enzyme
Q9NRR6	BXGT021193	Phosphatidylinositol polyphosphate 5-phosphatase type IV	56623	reviewed
Q9Y547	BXGT022288	Intraflagellar transport protein 25 homolog	51668	reviewed
Q9Y646	BXGT022317	Carboxypeptidase Q	10404	reviewed	Enzyme
Q9H694	BXGT024116	Protein bicaudal C homolog 1	80114	reviewed	Transporter
Q9HCK4	BXGT024280	Roundabout homolog 2	6092	reviewed
Q86SG6	BXGT026136	Serine/threonine-protein kinase Nek8	284086	reviewed	Kinase

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}