adisease

Showing entry for Manic Disorder

General Disease Information
BXGD Id	BXGD001799
Disease Name	Manic Disorder
Disease CUI Id	C0024713
MeSH Codes	F03
Disease Class Name	Mental Disorders
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:150
Disease Ontology Class Name	disease of mental health
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14594	BXGT004073	Neurocan core protein	1463	reviewed	Extracellular structure
O94759	BXGT005327	Transient receptor potential cation channel subfamily M member 2	7226	reviewed	Ion channel
O95864	BXGT005403	Acyl-CoA 6-desaturase	9415	reviewed
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01308	BXGT005749	Insulin	3630	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P11498	BXGT007714	Pyruvate carboxylase, mitochondrial	5091	reviewed	Enzyme
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13637	BXGT007933	Sodium/potassium-transporting ATPase subunit alpha-3	478	reviewed	Transporter
P17516	BXGT008313	Aldo-keto reductase family 1 member C4	1109	reviewed	Enzyme
P19404	BXGT008477	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	4729	reviewed
P19827	BXGT008523	Inter-alpha-trypsin inhibitor heavy chain H1	3697	reviewed	Enzyme modulator
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P21918	BXGT008708	D(1B) dopamine receptor	1816	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P23368	BXGT008856	NAD-dependent malic enzyme, mitochondrial	4200	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P25103	BXGT009020	Substance-P receptor	6869	reviewed	G-protein coupled receptor
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P49840	BXGT010749	Glycogen synthase kinase-3 alpha	2931	reviewed	Kinase
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P60880	BXGT011335	Synaptosomal-associated protein 25	6616	reviewed	Transporter
P78362	BXGT011839	SRSF protein kinase 2	6733	reviewed	Kinase
Q01668	BXGT012605	Voltage-dependent L-type calcium channel subunit alpha-1D	776	reviewed	Ion channel
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q07343	BXGT012926	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	5142	reviewed
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q12879	BXGT013275	Glutamate receptor ionotropic, NMDA 2A	2903	reviewed	Ion channel
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	2898	reviewed	Ion channel
Q13043	BXGT013307	Serine/threonine-protein kinase 4	6789	reviewed	Kinase
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	775	reviewed	Ion channel
Q15349	BXGT013558	Ribosomal protein S6 kinase alpha-2	6196	reviewed	Kinase
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q96CW9	BXGT019634	Netrin-G2	84628	reviewed	Enzyme modulator
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q9UQL6	BXGT021813	Histone deacetylase 5	10014	reviewed	Epigenetic regulator
Q9UQM7	BXGT021814	Calcium/calmodulin-dependent protein kinase type II subunit alpha	815	reviewed	Kinase
Q9Y2I2	BXGT022236	Netrin-G1	22854	reviewed	Enzyme modulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}