Showing entry for Osteitis Deformans


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002135
Disease NameOsteitis Deformans
Disease CUI IdC0029401
MeSH Codes C05  
Disease Class NameMusculoskeletal Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 5170 reviewed Kinase
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02818 BXGT005969 Osteocalcin 632 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05787 BXGT006385 Keratin, type II cytoskeletal 8 3856 reviewed
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08700 BXGT006816 Interleukin-3 3562 reviewed
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09651 BXGT006913 Heterogeneous nuclear ribonucleoprotein A1 3178 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P15941 BXGT008176 Mucin-1 4582 reviewed
P17544 BXGT008316 Cyclic AMP-dependent transcription factor ATF-7 11016 reviewed Transcription factor
P17676 BXGT008327 CCAAT/enhancer-binding protein beta 1051 reviewed Transcription factor
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P22626 BXGT008787 Heterogeneous nuclear ribonucleoproteins A2/B1 3181 reviewed
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P31391 BXGT009535 Somatostatin receptor type 4 6754 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P55055 BXGT011101 Oxysterols receptor LXR-beta 7376 reviewed Nuclear receptor
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P68133 BXGT011578 Actin, alpha skeletal muscle 58 reviewed Cellular structure
P68363 BXGT011594 Tubulin alpha-1B chain 10376 reviewed Cellular structure
P78344 BXGT011835 Eukaryotic translation initiation factor 4 gamma 2 1982 reviewed Nucleic acid binding
Q00653 BXGT012541 Nuclear factor NF-kappa-B p100 subunit 4791 reviewed Transcription factor
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q14117 BXGT013443 Dihydropyrimidinase 1807 reviewed Enzyme
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16769 BXGT013665 Glutaminyl-peptide cyclotransferase 25797 reviewed Enzyme
Q676U5 BXGT016177 Autophagy-related protein 16-1 55054 reviewed
Q71U36 BXGT016705 Tubulin alpha-1A chain 7846 reviewed Cellular structure
Q92835 BXGT019382 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 3635 reviewed
Q99519 BXGT019928 Sialidase-1 4758 reviewed Enzyme
Q9HCE7 BXGT020532 E3 ubiquitin-protein ligase SMURF1 57154 reviewed Enzyme
Q9Y223 BXGT022207 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase 10020 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
P29590 BXGT024350 Protein PML 5371 reviewed
Q8NEZ4 BXGT024850 Histone-lysine N-methyltransferase 2C 58508 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease