adisease

Showing entry for Osteopetrosis

General Disease Information
BXGD Id	BXGD002155
Disease Name	Osteopetrosis
Disease CUI Id	C0029454
MeSH Codes	C05
Disease Class Name	Musculoskeletal Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000924
Human Phenotype Ontology Term	Abnormality of the skeletal system
Disease Ontology Id	DOID:630 DOID:7
Disease Ontology Class Name	genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O43914	BXGT004635	TYRO protein tyrosine kinase-binding protein	7305	reviewed
O75030	BXGT005096	Microphthalmia-associated transcription factor	4286	reviewed
O75475	BXGT005130	PC4 and SFRS1-interacting protein	11168	reviewed	Signaling
O95644	BXGT005389	Nuclear factor of activated T-cells, cytoplasmic 1	4772	reviewed	Transcription factor
P00918	BXGT005690	Carbonic anhydrase 2	760	reviewed
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P12277	BXGT007789	Creatine kinase B-type	1152	reviewed	Kinase
P12931	BXGT007859	Proto-oncogene tyrosine-protein kinase Src	6714	reviewed	Kinase
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P84077	BXGT012031	ADP-ribosylation factor 1	375	reviewed
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q02790	BXGT012672	Peptidyl-prolyl cis-trans isomerase FKBP4	2288	reviewed	Enzyme
Q05315	BXGT012811	Galectin-10	1178	reviewed	Signaling
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q15392	BXGT013566	Delta(24)-sterol reductase	1718	reviewed	Enzyme
Q9HCR9	BXGT020537	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	50940	reviewed
Q9UBQ6	BXGT021660	Exostosin-like 2	2135	reviewed
Q9Y5X0	BXGT022305	Sorting nexin-10	29887	reviewed
Q9Y6K9	BXGT022333	NF-kappa-B essential modulator	8517	reviewed	Kinase
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
P35523	BXGT023831	Chloride channel protein 1	1180	reviewed	Ion channel
P51798	BXGT026083	H(+)/Cl(-) exchange transporter 7	1186	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}