Showing entry for Pituitary Neoplasms


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002321
Disease NamePituitary Neoplasms
Disease CUI IdC0032019
MeSH Codes C04   C10   C19  
Disease Class NameNeoplasms; Nervous System Diseases; Endocrine System Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0000818   HP:0002664  
Human Phenotype Ontology TermAbnormality of the endocrine system; Neoplasm
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00255 BXGT003903 Menin 4221 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O95067 BXGT005347 G2/mitotic-specific cyclin-B2 9133 reviewed Enzyme modulator
O95257 BXGT005365 Growth arrest and DNA damage-inducible protein GADD45 gamma 10912 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P07711 BXGT006661 Cathepsin L1 1514 reviewed Enzyme
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10828 BXGT007624 Thyroid hormone receptor beta 7068 reviewed Nuclear receptor
P11137 BXGT007656 Microtubule-associated protein 2 4133 reviewed
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12830 BXGT007852 Cadherin-1 999 reviewed
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 1385 reviewed
P22455 BXGT008772 Fibroblast growth factor receptor 4 2264 reviewed Kinase
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24557 BXGT008976 Thromboxane-A synthase 6916 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30872 BXGT009474 Somatostatin receptor type 1 6751 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35346 BXGT009813 Somatostatin receptor type 5 6755 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61978 BXGT011399 Heterogeneous nuclear ribonucleoprotein K 3190 reviewed Enzyme
P80365 BXGT011895 Corticosteroid 11-beta-dehydrogenase isozyme 2 3291 reviewed Enzyme
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q08345 BXGT012982 Epithelial discoidin domain-containing receptor 1 780 reviewed Kinase
Q13118 BXGT013312 Krueppel-like factor 10 7071 reviewed Nucleic acid binding
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13309 BXGT013338 S-phase kinase-associated protein 2 6502 reviewed
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q59FK2 BXGT015276 Selenocysteine lyase variant 51540 unreviewed
Q96DB2 BXGT019639 Histone deacetylase 11 79885 reviewed Epigenetic regulator
Q96I15 BXGT019674 Selenocysteine lyase 51540 reviewed Enzyme
Q9NP72 BXGT021144 Ras-related protein Rab-18 22931 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
Q9Y5W5 BXGT022303 Wnt inhibitory factor 1 11197 reviewed Calcium-binding protein
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease