Showing entry for Somatostatin receptor type 5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009813
Protein NameSomatostatin receptor type 5
Uniport IdP35346
GeneSSTR5
Gene Id6755
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071385 cellular response to glucocorticoid stimulus
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0032467 positive regulation of cytokinesis
Biological Process GO:0050796 regulation of insulin secretion
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0042923 neuropeptide binding
molecular function GO:0042277 peptide binding
molecular function GO:0004994 somatostatin receptor activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001206 BXGD000033 Acromegaly Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007095 BXGD000423 Carcinoid Tumor Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0017150 BXGD001095 Gastrinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0017689 BXGD001148 Glucagonoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0021670 BXGD001509 insulinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0031511 BXGD002304 Pheochromocytoma Neoplasms
C0032000 BXGD002318 Pituitary Adenoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0032019 BXGD002321 Pituitary Neoplasms Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0033375 BXGD002405 Prolactinoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0037661 BXGD002696 Somatostatinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0085413 BXGD003171 Polycystic Kidney, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0206717 BXGD004263 Olfactory Neuroblastoma Neoplasms; Nervous System Diseases
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0221406 BXGD004459 Pituitary-dependent Cushing's disease Nervous System Diseases; Endocrine System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0238462 BXGD004937 Medullary carcinoma of thyroid Neoplasms; Endocrine System Diseases
C0242363 BXGD005156 Islet Cell Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0270823 BXGD006112 Petit mal status Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0271738 BXGD006253 Hypocortisolism secondary to another disorder Endocrine System Diseases
C0278864 BXGD006604 Growth Hormone-Producing Pituitary Gland Neoplasm Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0280280 BXGD006731 stage, prostate cancer Neoplasms; Male Urogenital Diseases
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0311335 BXGD006877 Grand Mal Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0338078 BXGD007166 Non-Functioning Pituitary Gland Neoplasm Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0346302 BXGD007807 Growth Hormone-Secreting Pituitary Adenoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0346303 BXGD007808 Thyrotroph adenoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0393734 BXGD008131 Complex Partial Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0751522 BXGD010488 Status Epilepticus, Subclinical Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751523 BXGD010489 Non-Convulsive Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751524 BXGD010490 Simple Partial Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0948387 BXGD011535 Secondary Adrenal Insufficiency Endocrine System Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1306214 BXGD012356 ACTH-Secreting Pituitary Adenoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1337011 BXGD012874 Well Differentiated Pancreatic Endocrine Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1622510 BXGD013473 Neurocytoma Neoplasms; Nervous System Diseases
C1839839 BXGD014416 MAJOR AFFECTIVE DISORDER 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders
C1852197 BXGD015264 MAJOR AFFECTIVE DISORDER 1 Mental Disorders
C1970943 BXGD016852 MAJOR AFFECTIVE DISORDER 4 Mental Disorders
C1970945 BXGD016853 MAJOR AFFECTIVE DISORDER 6 Mental Disorders
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C4551683 BXGD023389 Adrenal Gland Pheochromocytoma Neoplasms; Endocrine System Diseases
C4552000 BXGD023473 Episodic Kinesigenic Dyskinesia 1 Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0016470 Camptothecin 348.11
BXGC0051425 Combretastatin A-1 332.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein