adisease

Showing entry for Iron deficiency

General Disease Information
BXGD Id	BXGD005016
Disease Name	Iron deficiency
Disease CUI Id	C0240066
MeSH Codes	C18
Disease Class Name	Nutritional and Metabolic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O15379	BXGT004159	Histone deacetylase 3	8841	reviewed	Epigenetic regulator
O43293	BXGT004584	Death-associated protein kinase 3	1613	reviewed	Kinase
O75475	BXGT005130	PC4 and SFRS1-interacting protein	11168	reviewed	Signaling
O75716	BXGT005147	Serine/threonine-protein kinase 16	8576	reviewed	Kinase
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04156	BXGT006156	Major prion protein	5621	reviewed
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06744	BXGT006494	Glucose-6-phosphate isomerase	2821	reviewed	Enzyme
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P14550	BXGT008019	Aldo-keto reductase family 1 member A1	10327	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P18848	BXGT008432	Cyclic AMP-dependent transcription factor ATF-4	468	reviewed
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P21399	BXGT008646	Cytoplasmic aconitate hydratase	48	reviewed	Enzyme
P21673	BXGT008676	Diamine acetyltransferase 1	6303	reviewed
P22830	BXGT008809	Ferrochelatase, mitochondrial	2235	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	328	reviewed
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P35475	BXGT009837	Alpha-L-iduronidase	3425	reviewed	Enzyme
P35613	BXGT009856	Basigin	682	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P49281	BXGT010689	Natural resistance-associated macrophage protein 2	4891	reviewed	Transporter
P51572	BXGT010859	B-cell receptor-associated protein 31	10134	reviewed	Transporter
P51668	BXGT010875	Ubiquitin-conjugating enzyme E2 D1	7321	reviewed	Enzyme
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P78417	BXGT011843	Glutathione S-transferase omega-1	9446	reviewed
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P81172	BXGT011935	Hepcidin	57817	reviewed
Q00532	BXGT012532	Cyclin-dependent kinase-like 1	8814	reviewed	Kinase
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13946	BXGT013406	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	5150	reviewed
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16595	BXGT013643	Frataxin, mitochondrial	2395	reviewed	Enzyme
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q53TN4	BXGT015019	Cytochrome b reductase 1	79901	reviewed	Enzyme
Q6NYC1	BXGT016436	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	23210	reviewed	Receptor
Q6ZVN8	BXGT016641	Hemojuvelin	148738	reviewed
Q7Z2H8	BXGT017247	Proton-coupled amino acid transporter 1	206358	reviewed	Transporter
Q8IXJ6	BXGT018362	NAD-dependent protein deacetylase sirtuin-2	22933	reviewed	Epigenetic regulator
Q8WWM9	BXGT019001	Cytoglobin	114757	reviewed
Q92945	BXGT019397	Far upstream element-binding protein 2	8570	reviewed	Enzyme
Q96QV1	BXGT019722	Hedgehog-interacting protein	64399	reviewed
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q99873	BXGT019972	Protein arginine N-methyltransferase 1	3276	reviewed	Epigenetic regulator
Q9BYT8	BXGT020190	Neurolysin, mitochondrial	57486	reviewed	Enzyme
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9UKU7	BXGT021749	Isobutyryl-CoA dehydrogenase, mitochondrial	27034	reviewed	Enzyme
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9Y286	BXGT022225	Sialic acid-binding Ig-like lectin 7	27036	reviewed	Receptor
Q9Y3B4	BXGT022255	Splicing factor 3B subunit 6	51639	reviewed
Q9Y6F1	BXGT022328	Protein mono-ADP-ribosyltransferase PARP3	10039	reviewed
O60936	BXGT022857	Nucleolar protein 3	8996	reviewed
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P27918	BXGT025485	Properdin	5199	reviewed
Q8IZL9	BXGT026139	Cyclin-dependent kinase 20	23552	reviewed	Kinase
P07320	BXGT026150	Gamma-crystallin D	1421	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}