Showing entry for Malignant Fibrous Histiocytoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD007076
Disease NameMalignant Fibrous Histiocytoma
Disease CUI IdC0334463
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
A1Z1Q3 BXGT001069 ADP-ribose glycohydrolase MACROD2 140733 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O75030 BXGT005096 Microphthalmia-associated transcription factor 4286 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O95407 BXGT005380 Tumor necrosis factor receptor superfamily member 6B 8771 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P07332 BXGT006601 Tyrosine-protein kinase Fes/Fps 2242 reviewed Kinase
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08397 BXGT006768 Porphobilinogen deaminase 3145 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14324 BXGT008005 Farnesyl pyrophosphate synthase 2224 reviewed Enzyme
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30989 BXGT009492 Neurotensin receptor type 1 4923 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P37023 BXGT009953 Serine/threonine-protein kinase receptor R3 94 reviewed Kinase
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61626 BXGT011382 Lysozyme C 4069 reviewed
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase 7486 reviewed Enzyme
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q8TAF3 BXGT018786 WD repeat-containing protein 48 57599 reviewed
Q969Q1 BXGT019610 E3 ubiquitin-protein ligase TRIM63 84676 reviewed
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9Y3B4 BXGT022255 Splicing factor 3B subunit 6 51639 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q99958 BXGT023732 Forkhead box protein C2 2303 reviewed Transcription factor
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
O14958 BXGT025138 Calsequestrin-2 845 reviewed
Q9GZV5 BXGT025439 WW domain-containing transcription regulator protein 1 25937 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease