Showing entry for ADP-ribose glycohydrolase MACROD2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT001069
Protein NameADP-ribose glycohydrolase MACROD2
Uniport IdA1Z1Q3
GeneMACROD2
Gene Id140733
DomainMacro
Pfam PF01661  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007420 brain development
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0140291 peptidyl-glutamate ADP-deribosylation
Biological Process GO:0051725 protein de-ADP-ribosylation
Biological Process GO:0042278 purine nucleoside metabolic process
Biological Process GO:0009617 response to bacterium
molecular function GO:0140293 ADP-ribosylglutamate hydrolase activity
molecular function GO:0019213 deacetylase activity
molecular function GO:0016798 hydrolase activity, acting on glycosyl bonds
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0008074 BXGD000519 Child Development Disorders, Pervasive Mental Disorders
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0013170 BXGD000802 Drug habituation Chemically-Induced Disorders; Mental Disorders
C0013222 BXGD000805 Drug Use Disorders Chemically-Induced Disorders; Mental Disorders
C0017654 BXGD001136 Glomerular Filtration Rate
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0025362 BXGD001866 Mental Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029231 BXGD002125 Organic Mental Disorders, Substance-Induced Chemically-Induced Disorders; Mental Disorders
C0038580 BXGD002771 Substance Dependence Chemically-Induced Disorders; Mental Disorders
C0038586 BXGD002772 Substance Use Disorders Chemically-Induced Disorders; Mental Disorders
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0200665 BXGD004045 Platelet mean volume determination (procedure)
C0201534 BXGD004049 Antiphospholipid antibodies measurement
C0206762 BXGD004290 Limb Deformities, Congenital Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0236773 BXGD004827 Depressed bipolar I disorder Mental Disorders
C0236969 BXGD004842 Substance-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0278480 BXGD006510 Stage III Colon Cancer Digestive System Diseases; Neoplasms
C0334463 BXGD007076 Malignant Fibrous Histiocytoma Neoplasms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0424574 BXGD008534 Duration of sleep
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0524957 BXGD009252 Corneal Topography
C0562350 BXGD009476 Hip circumference
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0596887 BXGD009648 mathematical ability
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0740858 BXGD010012 Substance abuse problem Chemically-Induced Disorders; Mental Disorders
C0796004 BXGD010776 Kabuki make-up syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Otorhinolaryngologic Diseases; Hemic and Lymphatic Diseases
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1314691 BXGD012388 Age at menarche Behavior and Behavior Mechanisms
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C2697758 BXGD017432 Interleukin 10 Measurement
C2985280 BXGD018223 Blood Protein Measurement
C3146254 BXGD018263 Stage III Colon Cancer AJCC v7
C3495928 BXGD019014 Thyroid associated orbitopathy
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3808986 BXGD019564 HYPOGONADOTROPIC HYPOGONADISM 21 WITH OR WITHOUT ANOSMIA
C4016902 BXGD020386 HYPOGONADOTROPIC HYPOGONADISM 21 WITH ANOSMIA, SUSCEPTIBILITY TO
C4316881 BXGD022709 Prescription Drug Abuse Chemically-Induced Disorders; Mental Disorders
C4525124 BXGD023120 Stage III Colon Cancer AJCC v8
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein