adisease

Showing entry for Opiate Addiction

General Disease Information
BXGD Id	BXGD009238
Disease Name	Opiate Addiction
Disease CUI Id	C0524662
MeSH Codes	C25 F03
Disease Class Name	Chemically-Induced Disorders; Mental Disorders
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:150
Disease Ontology Class Name	disease of mental health
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00222	BXGT003899	Metabotropic glutamate receptor 8	2918	reviewed	G-protein coupled receptor
O15303	BXGT004150	Metabotropic glutamate receptor 6	2916	reviewed	G-protein coupled receptor
O15399	BXGT004164	Glutamate receptor ionotropic, NMDA 2D	2906	reviewed	Ion channel
O43612	BXGT004605	Orexin	3060	reviewed
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P02748	BXGT005940	Complement component C9	735	reviewed
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14616	BXGT008026	Insulin receptor-related protein	3645	reviewed	Kinase
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P21917	BXGT008707	D(4) dopamine receptor	1815	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P23141	BXGT008830	Liver carboxylesterase 1	1066	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P34947	BXGT009774	G protein-coupled receptor kinase 5	2869	reviewed	Kinase
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35462	BXGT009835	D(3) dopamine receptor	1814	reviewed	G-protein coupled receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P41143	BXGT010223	Delta-type opioid receptor	4985	reviewed	G-protein coupled receptor
P41145	BXGT010225	Kappa-type opioid receptor	4986	reviewed	G-protein coupled receptor
P41146	BXGT010226	Nociceptin receptor	4987	reviewed	G-protein coupled receptor
P42261	BXGT010293	Glutamate receptor 1	2890	reviewed	Ion channel
P43354	BXGT010381	Nuclear receptor subfamily 4 group A member 2	4929	reviewed	Nuclear receptor
P46098	BXGT010507	5-hydroxytryptamine receptor 3A	3359	reviewed	Ion channel
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q05940	BXGT012846	Synaptic vesicular amine transporter	6571	reviewed	Transporter
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	5530	reviewed
Q08828	BXGT013008	Adenylate cyclase type 1	107	reviewed
Q12879	BXGT013275	Glutamate receptor ionotropic, NMDA 2A	2903	reviewed	Ion channel
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13451	BXGT013356	Peptidyl-prolyl cis-trans isomerase FKBP5	2289	reviewed	Enzyme
Q14831	BXGT013506	Metabotropic glutamate receptor 7	2917	reviewed	G-protein coupled receptor
Q16568	BXGT013640	Cocaine- and amphetamine-regulated transcript protein	9607	reviewed
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8NFD2	BXGT018559	Ankyrin repeat and protein kinase domain-containing protein 1	255239	reviewed	Kinase
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BYT8	BXGT020190	Neurolysin, mitochondrial	57486	reviewed	Enzyme
Q9Y2I1	BXGT022235	Nischarin	11188	reviewed	Enzyme modulator
P17752	BXGT023118	Tryptophan 5-hydroxylase 1	7166	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}