Showing entry for 5-hydroxytryptamine receptor 3A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010507
Protein Name5-hydroxytryptamine receptor 3A
Uniport IdP46098
GeneHTR3A
Gene Id3359
DomainNeur_chan_LBD; Neur_chan_memb
Pfam PF02931   PF02932  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.6 Nervous system hsa04726 Serotonergic synapse
5. Organismal Systems 5.7 Sensory system hsa04742 Taste transduction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071363 cellular response to growth factor stimulus
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0050877 nervous system process
Biological Process GO:0032414 positive regulation of ion transmembrane transporter activity
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0042220 response to cocaine
Biological Process GO:0045471 response to ethanol
Biological Process GO:0007165 signal transduction
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0051378 serotonin binding
molecular function GO:0022850 serotonin-gated cation-selective channel activity
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0030424 axon
cellular component GO:0032154 cleavage furrow
cellular component GO:0005737 cytoplasm
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:1904602 serotonin-activated cation-selective channel complex
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002792 BXGD000129 anaphylaxis Immune System Diseases
C0003125 BXGD000179 Anorexia Nervosa Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006012 BXGD000360 Borderline Personality Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0008060 BXGD000516 child abuse behavior
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0013395 BXGD000831 Dyspepsia Pathological Conditions, Signs and Symptoms
C0016053 BXGD001041 Fibromyalgia Musculoskeletal Diseases; Nervous System Diseases
C0019337 BXGD001319 Heroin Dependence Chemically-Induced Disorders; Mental Disorders
C0020449 BXGD001387 Hyperdistention Pathological Conditions, Signs and Symptoms
C0021167 BXGD001487 Incontinence Nervous System Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0024591 BXGD001789 Malignant hyperpyrexia due to anesthesia Pathological Conditions, Signs and Symptoms
C0027497 BXGD001993 Nausea Pathological Conditions, Signs and Symptoms
C0027498 BXGD001994 Nausea and vomiting Pathological Conditions, Signs and Symptoms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028043 BXGD002066 Nicotine Dependence Chemically-Induced Disorders; Mental Disorders
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028768 BXGD002084 Obsessive-Compulsive Disorder Mental Disorders
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030319 BXGD002208 Panic Disorder Mental Disorders
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0038443 BXGD002757 Stress, Psychological Behavior and Behavior Mechanisms
C0040517 BXGD002872 Gilles de la Tourette syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042693 BXGD002996 Violence
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0151718 BXGD003464 Hypocholesterolemia Nutritional and Metabolic Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0236733 BXGD004822 Amphetamine-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0236804 BXGD004835 Amphetamine Addiction Chemically-Induced Disorders; Mental Disorders
C0236807 BXGD004836 Amphetamine Abuse Chemically-Induced Disorders; Mental Disorders
C0239377 BXGD004980 Arm Pain Pathological Conditions, Signs and Symptoms
C0266427 BXGD005665 Testicular regression syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0438696 BXGD008805 Suicidal Behavior and Behavior Mechanisms
C0520904 BXGD009121 Postoperative Nausea Pathological Conditions, Signs and Symptoms
C0520905 BXGD009122 Vomiting, Postoperative Pathological Conditions, Signs and Symptoms
C0520909 BXGD009123 Postoperative Nausea and Vomiting Pathological Conditions, Signs and Symptoms
C0524662 BXGD009238 Opiate Addiction Chemically-Induced Disorders; Mental Disorders
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0677936 BXGD009737 Refractory cancer Neoplasms
C0686347 BXGD009832 Tardive Dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0687132 BXGD009839 heavy drinking
C1262211 BXGD011876 Diarrhoea predominant irritable bowel syndrome
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1659098 BXGD013487 Complete paraplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1839839 BXGD014416 MAJOR AFFECTIVE DISORDER 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mental Disorders
C1852197 BXGD015264 MAJOR AFFECTIVE DISORDER 1 Mental Disorders
C1970943 BXGD016852 MAJOR AFFECTIVE DISORDER 4 Mental Disorders
C1970945 BXGD016853 MAJOR AFFECTIVE DISORDER 6 Mental Disorders
C2267227 BXGD017015 Bulimia Nervosa Mental Disorders
C2700438 BXGD017469 MAJOR AFFECTIVE DISORDER 7 Mental Disorders
C2700439 BXGD017470 MAJOR AFFECTIVE DISORDER 8 Mental Disorders
C2700440 BXGD017471 MAJOR AFFECTIVE DISORDER 9 Mental Disorders
C2745900 BXGD017568 Promyelocytic leukemia
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3544321 BXGD019114 Treatment-resistant schizophrenia
C3714760 BXGD019432 Drug-induced tardive dyskinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000191 Tyramine 137.18
BXGC0000226 Glycine 75.07
BXGC0000434 Ethanol 46.07
BXGC0000651 Harmalan 184.24
BXGC0000982 L-Homocysteine 135.19
BXGC0001545 Harmine 212.25
BXGC0002796 Nicotine 162.23
BXGC0003066 Phenols 199.27
BXGC0003102 Acetylcholine 146.21
BXGC0003196 Aripiprazole 448.39
BXGC0004665 4-Aminobutyric acid 103.12
BXGC0004763 Octopamine 153.18
BXGC0005683 Quercetin 302.24
BXGC0005867 Serotonin 176.22
BXGC0005871 Dopamine 153.18
BXGC0005874 Racemethionine 149.21
BXGC0006183 L-Cystine 240.3
BXGC0007601 1,8-Cineole 154.25
BXGC0007821 Linalool 154.25
BXGC0017369 N-Methyllaurotetanine 341.16
BXGC0018580 octopaminium 154.09
BXGC0038837 Pseudohypericin 520.08
BXGC0040150 Cannabidiol 314.22
BXGC0040582 nantenine 339.15
BXGC0042462 Cysteine 121.02
BXGC0042510 Fluoxetine 309.13
BXGC0043578 5-Hydroxy-2-(2-Phenylethyl)Chromen-4-One 266.09
BXGC0047402 Acridine 179.07
BXGC0052646 Tubocurarine 609.3
BXGC0052798 5-Meo-Dmt 218.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein